PMID- 36459889 OWN - NLM STAT- MEDLINE DCOM- 20230227 LR - 20230227 IS - 1877-0665 (Electronic) IS - 1877-0657 (Linking) VI - 66 IP - 1 DP - 2023 Feb TI - Functional recovery after total hip/knee replacement in obese people: A systematic review. PG - 101710 LID - S1877-0657(22)00082-3 [pii] LID - 10.1016/j.rehab.2022.101710 [doi] AB - OBJECTIVE: Several studies have investigated the influence of body mass index (BMI) on functional gain after total hip replacement (THR) or total knee replacement (TKR) in osteoarthritis, with contradictory results. This systematic literature review was conducted to ascertain whether obesity affects functional recovery after THR or TKR in the short (<1 year), medium (<3 years) and long term (>3 years). METHODS: The study was registered with PROSPERO and conducted according to the PRISMA guidelines. A systematic literature search was conducted across Medline and EMBASE databases for articles published between 1980 and 2020 that investigated patient-reported measures of functional recovery after THR and TKR in participants with osteoarthritis and obesity (defined as BMI >/=30 kg/m(2)). RESULTS: Twenty-six articles reporting on 68,840 persons (34,955 for THR and 33,885 for TKR) were included in the final analysis: 5 case-control studies, 21 cohort studies (9 for THR only, 10 for TKR only and 2 for both). The average minimum follow-up was 36.4 months, ranging from 6 weeks to 10 years. Most studies found significantly lower pre-operative patient-reported functional scores for participants with obesity. After THR, there was a small difference in functional recovery in favor of those without obesity in the short term (<6 months), but the difference remained below the minimal clinically important difference (MCID) threshold and disappeared in the medium and long term. After TKR, functional recovery was better for those with obesity than those without in the first year, similar until the third year, and then decreased thereafter. CONCLUSIONS: Although there is a paucity of high-quality evidence, our findings show substantial functional gains in people with obesity after total joint replacement. Functional recovery after THR or TKR does not significantly differ, or only slightly differs, between those with and without obesity, and the difference in functional gain is not clinically important. PROSPERO NUMBER: CRD42018112919. CI - Copyright (c) 2022 Elsevier Masson SAS. All rights reserved. FAU - Courtine, Matthieu AU - Courtine M AD - Dijon university hospital, Department of Orthopaedic surgery, CHU Dijon-Bourgogne, France. FAU - Bourredjem, Abderrahmane AU - Bourredjem A AD - INSERM, Universite de Bourgogne, CIC 1432, Module Epidemiologie Clinique, Dijon, France. FAU - Gouteron, Anais AU - Gouteron A AD - INSERM UMR1093-CAPS, Universite de Bourgogne, UFR STAPS, Dijon, France; Dijon university hospital, Department of Physical Medicine and Rehabilitation, CHU Dijon-Bourgogne, Dijon, France. FAU - Fournel, Isabelle AU - Fournel I AD - INSERM, Universite de Bourgogne, CIC 1432, Module Epidemiologie Clinique, Dijon, France. FAU - Bartolone, Placido AU - Bartolone P AD - La Colline, Hirslanden Private Hospital Group, Geneva, Switzerland. FAU - Baulot, Emmanuel AU - Baulot E AD - Dijon university hospital, Department of Orthopaedic surgery, CHU Dijon-Bourgogne, France; INSERM UMR1093-CAPS, Universite de Bourgogne, UFR STAPS, Dijon, France. FAU - Ornetti, Paul AU - Ornetti P AD - INSERM UMR1093-CAPS, Universite de Bourgogne, UFR STAPS, Dijon, France; Dijon university hospital, Department of Rheumatology, CHU Dijon-Bourgogne, Dijon, France; INSERM, Universite de Bourgogne, CIC 1432, Module Plurithematique, Plateforme d'Investigation Technologique, CHU Dijon-Bourgogne, Dijon, France. Electronic address: paul.ornetti@chu-dijon.fr. FAU - Martz, Pierre AU - Martz P AD - Dijon university hospital, Department of Orthopaedic surgery, CHU Dijon-Bourgogne, France; INSERM UMR1093-CAPS, Universite de Bourgogne, UFR STAPS, Dijon, France; INSERM, Universite de Bourgogne, CIC 1432, Module Plurithematique, Plateforme d'Investigation Technologique, CHU Dijon-Bourgogne, Dijon, France. LA - eng PT - Journal Article PT - Review PT - Systematic Review DEP - 20221129 PL - Netherlands TA - Ann Phys Rehabil Med JT - Annals of physical and rehabilitation medicine JID - 101502773 SB - IM MH - Humans MH - *Arthroplasty, Replacement, Knee MH - *Arthroplasty, Replacement, Hip/methods MH - *Osteoarthritis, Knee MH - Obesity MH - Recovery of Function OTO - NOTNLM OT - Functional recovery OT - Obesity OT - Osteoarthritis OT - Systematic review OT - Total hip replacement OT - Total knee replacement EDAT- 2022/12/03 06:00 MHDA- 2023/03/03 06:00 CRDT- 2022/12/02 18:24 PHST- 2020/11/07 00:00 [received] PHST- 2022/08/04 00:00 [revised] PHST- 2022/09/24 00:00 [accepted] PHST- 2022/12/03 06:00 [pubmed] PHST- 2023/03/03 06:00 [medline] PHST- 2022/12/02 18:24 [entrez] AID - S1877-0657(22)00082-3 [pii] AID - 10.1016/j.rehab.2022.101710 [doi] PST - ppublish SO - Ann Phys Rehabil Med. 2023 Feb;66(1):101710. doi: 10.1016/j.rehab.2022.101710. Epub 2022 Nov 29.