PMID- 36468058
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20221206
IS  - 1664-2295 (Print)
IS  - 1664-2295 (Electronic)
IS  - 1664-2295 (Linking)
VI  - 13
DP  - 2022
TI  - Occlusion type and posterior communicating artery patency may predict favorable 
      outcome after endovascular thrombectomy in selective basilar top occlusion.
PG  - 1047971
LID - 10.3389/fneur.2022.1047971 [doi]
LID - 1047971
AB  - INTRODUCTION: The top of the basilar artery is a five-branched junction, 
      consisting of two superior cerebellar arteries (SCAs), two posterior cerebellar 
      arteries (PCAs), and the basilar artery itself. This study aimed to investigate 
      prognostic factors in patients with selective acute basilar top occlusion managed 
      with mechanical thrombectomy, focusing on occlusion type and posterior 
      communicating artery (PCoA) patency. METHODS: Eligible patients who underwent 
      endovascular treatment (EVT) for acute basilar top occlusion were reviewed. 
      Patterns of basilar top occlusion were categorized as types I-III according to 
      whether the SCA and PCA were visible on angiography. The PCoA was categorized as 
      hypoplastic or non-visible (type I), normal patency but non-visible PCA through 
      PCoA flow (type II), and fetal type (type III). RESULTS: Good outcomes were 
      observed in 50% (21/42) and mortality in 11.9% (5/42) of the cases at 90 days. 
      Patients with good outcomes showed lower baseline National Institutes of Health 
      Stroke Scale (NIHSS) score (P = 0.001) and a higher proportion of type III 
      basilar top occlusion (P = 0.004) and type III PCoA (P = 0.001). Multivariable 
      logistic analysis showed that baseline NIHSS score [odds ratio (OR), 0.84; 95% 
      confidence interval (CI), 0.73-0.97; P = 0.017) and type III PCoA (OR, 21.54, 95% 
      CI, 1.33-347.97; P = 0.031) were independent predictors of good functional 
      outcomes. CONCLUSION: A low initial NIHSS score and good PCoA patency were 
      independent predictors of favorable clinical outcomes after EVT in patients with 
      acute basilar top occlusion. Furthermore, the favorable outcome group showed a 
      high proportion of type III basilar top occlusions.
CI  - Copyright (c) 2022 Park, Im, Shin and Kang.
FAU - Park, Jung Soo
AU  - Park JS
AD  - Research Institute of Clinical Medicine of Jeonbuk National University Biomedical 
      Research Institute of Jeonbuk National University Hospital, Jeonju, South Korea.
AD  - Department of Neurosurgery, Jeonbuk National University Medical School and 
      Hospital, Jeonju, South Korea.
FAU - Im, Yong-Jin
AU  - Im YJ
AD  - Center for Clinical Pharmacology and Biomedical Research Institute, Jeonbuk 
      National University Hospital, Jeonju, South Korea.
FAU - Shin, Byoung-Soo
AU  - Shin BS
AD  - Research Institute of Clinical Medicine of Jeonbuk National University Biomedical 
      Research Institute of Jeonbuk National University Hospital, Jeonju, South Korea.
AD  - Department of Neurology, Jeonbuk National University Medical School and Hospital, 
      Jeonju, South Korea.
FAU - Kang, Hyun Goo
AU  - Kang HG
AD  - Research Institute of Clinical Medicine of Jeonbuk National University Biomedical 
      Research Institute of Jeonbuk National University Hospital, Jeonju, South Korea.
AD  - Department of Neurology, Jeonbuk National University Medical School and Hospital, 
      Jeonju, South Korea.
LA  - eng
PT  - Journal Article
DEP - 20221117
PL  - Switzerland
TA  - Front Neurol
JT  - Frontiers in neurology
JID - 101546899
PMC - PMC9716350
OTO - NOTNLM
OT  - basilar artery
OT  - ischemic stroke
OT  - outcome
OT  - posterior communicating artery
OT  - thrombectomy
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2022/12/06 06:00
MHDA- 2022/12/06 06:01
PMCR- 2022/11/17
CRDT- 2022/12/05 04:36
PHST- 2022/09/19 00:00 [received]
PHST- 2022/11/07 00:00 [accepted]
PHST- 2022/12/05 04:36 [entrez]
PHST- 2022/12/06 06:00 [pubmed]
PHST- 2022/12/06 06:01 [medline]
PHST- 2022/11/17 00:00 [pmc-release]
AID - 10.3389/fneur.2022.1047971 [doi]
PST - epublish
SO  - Front Neurol. 2022 Nov 17;13:1047971. doi: 10.3389/fneur.2022.1047971. 
      eCollection 2022.