PMID- 36472225 OWN - NLM STAT- MEDLINE DCOM- 20230131 LR - 20230329 IS - 1552-3799 (Electronic) IS - 1054-7738 (Linking) VI - 32 IP - 2 DP - 2023 Feb TI - The Association of Glucose Variability and Dementia Incidence in Latinx Adults with Type 2 Diabetes: A Retrospective Study. PG - 249-255 LID - 10.1177/10547738221141232 [doi] AB - Latinx adults with both cognitive dysfunction and type 2 diabetes mellitus (T2DM) are significantly more likely than Latinx adults with diabetes alone to have complications such as cardiovascular disease. Glucose variability may be a risk for dementia, but the course of glucose variability in the time before a dementia diagnosis for Latinx adults with T2DM has not been examined. We used a 10-year retrospective cohort of medical records of Latinx patients with T2DM who had at least one use of a continuous glucose monitor. The objective was to examine how glucose variability was associated with future dementia diagnoses. A total of 116 charts were included. Mean of daily differences and mean amplitude of glycemic excursions were more strongly associated with dementia diagnoses than other variability indices (p < .01). Understanding the relationships between cognitive function, glucose variability, and barriers to health care can translate into improved interventions to enhance diabetes care. FAU - Cuevas, Heather AU - Cuevas H AUID- ORCID: 0000-0003-4314-6686 AD - The University of Texas at Austin, School of Nursing, USA. FAU - Munoz, Elizabeth AU - Munoz E AD - The University of Texas at Austin, College of Natural Sciences, USA. FAU - Nagireddy, Divya AU - Nagireddy D AUID- ORCID: 0000-0002-1252-4907 AD - The University of Texas at Austin, College of Natural Sciences, USA. FAU - Kim, Jeeyeon AU - Kim J AUID- ORCID: 0000-0001-7913-4463 AD - The University of Texas at Austin, School of Nursing, USA. FAU - Ganucheau, Grace AU - Ganucheau G AD - The University of Texas at Austin, School of Nursing, USA. FAU - Alomoush, Fathia AU - Alomoush F AD - The University of Texas at Austin, School of Nursing, USA. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20221206 PL - United States TA - Clin Nurs Res JT - Clinical nursing research JID - 9208508 RN - IY9XDZ35W2 (Glucose) RN - 0 (Glycated Hemoglobin) RN - 0 (Blood Glucose) MH - Humans MH - Adult MH - *Diabetes Mellitus, Type 2/complications/psychology MH - Retrospective Studies MH - Glucose MH - Incidence MH - Glycated Hemoglobin MH - Blood Glucose MH - *Dementia/epidemiology MH - Hispanic or Latino OTO - NOTNLM OT - Latinx OT - cognitive function OT - glucose variability OT - type 2 diabetes EDAT- 2022/12/07 06:00 MHDA- 2023/02/01 06:00 CRDT- 2022/12/06 05:42 PHST- 2022/12/07 06:00 [pubmed] PHST- 2023/02/01 06:00 [medline] PHST- 2022/12/06 05:42 [entrez] AID - 10.1177/10547738221141232 [doi] PST - ppublish SO - Clin Nurs Res. 2023 Feb;32(2):249-255. doi: 10.1177/10547738221141232. Epub 2022 Dec 6.