PMID- 36472649 OWN - NLM STAT- MEDLINE DCOM- 20230207 LR - 20230626 IS - 1432-1076 (Electronic) IS - 0340-6199 (Print) IS - 0340-6199 (Linking) VI - 182 IP - 2 DP - 2023 Feb TI - The value of modified Ross score in the evaluation of children with severe lower respiratory tract infection admitted to the pediatric intensive care unit. PG - 741-747 LID - 10.1007/s00431-022-04737-9 [doi] AB - Heart failure (HF) represents an important cause of morbidity and mortality in children. It is mostly caused by congenital heart disease (CHD) and cardiomyopathy. The Ross HF classification was developed to assess severity in infants and has subsequently been modified to apply to all pediatric ages. The modified Ross classification for children provides a numeric score comparable with the New York Heart Association (NYHA) HF classification for adults. The aim of this work is to investigate the role of modified Ross score in the evaluation of children with severe lower respiratory tract infection admitted to the pediatric intensive care unit (PICU). One hundred and sixty-four children with severe LRTI admitted to the PICU were enrolled in this prospective cohort study, which was carried out at Assiut University Children Hospital, from the start of July 2021 up to the end of December 2021. Sixty patients (36.6%) of studied cases with severe LRTI admitted to PICU had HF. Out of these, 37 (61.7%) had mild HF; 17 (28.3%) had moderate HF, while six cases (10%) had severe HF according to the modified Ross score. The value of modified Ross score was significantly higher in children with heart failure with sensitivity and specificity 100% with cutoff value of 2. Admission to NICU, history of previous ventilation, and prematurity were higher in patients who developed HF. Patients with pulmonary hypertension (PH) and those with raised neutrophil lymphocyte ratio were significantly higher in the group of patients with moderate and severe degree of HF. Conclusion: Modified Ross score is a simple clinical score which may help in assessing and predicting children with severe LRTI. What is Known: * Hear failure is common complication to lower respiratory tract infection. * Modified Ross score was used to predict and classify heart failure in adult with lower respiratory infection. What is New: * Modified Ross score found to be of value in prediction of heart failure in children with lower respiratory tract infection. CI - (c) 2022. The Author(s). FAU - Hassan, Enas Saad AU - Hassan ES AD - Pediatric Department, Faculty of Medicine, Assiut University, Assiut, 71515, Egypt. FAU - Ahmad, Salah-Eldin Amry AU - Ahmad SA AD - Pediatric Department, Faculty of Medicine, Assiut University, Assiut, 71515, Egypt. FAU - Mohamad, Ismail Lotfy AU - Mohamad IL AD - Pediatric Department, Faculty of Medicine, Assiut University, Assiut, 71515, Egypt. ismail231@aun.edu.eg. FAU - Ahmad, Faisal-Alkhateeb AU - Ahmad FA AD - Pediatric Department, Faculty of Medicine, Assiut University, Assiut, 71515, Egypt. LA - eng PT - Journal Article DEP - 20221206 PL - Germany TA - Eur J Pediatr JT - European journal of pediatrics JID - 7603873 SB - IM MH - Infant MH - Child MH - Humans MH - Prospective Studies MH - *Heart Failure/etiology MH - Hospitalization MH - *Respiratory Tract Infections/complications/diagnosis MH - Intensive Care Units, Pediatric PMC - PMC9899196 OTO - NOTNLM OT - Heart failure OT - Lower respiratory tract infection OT - Modified Ross score OT - Pediatric COIS- The authors declare no competing interests. EDAT- 2022/12/07 06:00 MHDA- 2023/02/08 06:00 PMCR- 2022/12/06 CRDT- 2022/12/06 11:13 PHST- 2022/07/07 00:00 [received] PHST- 2022/11/27 00:00 [accepted] PHST- 2022/11/23 00:00 [revised] PHST- 2022/12/07 06:00 [pubmed] PHST- 2023/02/08 06:00 [medline] PHST- 2022/12/06 11:13 [entrez] PHST- 2022/12/06 00:00 [pmc-release] AID - 10.1007/s00431-022-04737-9 [pii] AID - 4737 [pii] AID - 10.1007/s00431-022-04737-9 [doi] PST - ppublish SO - Eur J Pediatr. 2023 Feb;182(2):741-747. doi: 10.1007/s00431-022-04737-9. Epub 2022 Dec 6.