PMID- 36473025
OWN - NLM
STAT- MEDLINE
DCOM- 20230227
LR  - 20230608
IS  - 1473-6322 (Electronic)
IS  - 1473-6322 (Linking)
VI  - 23
IP  - 2
DP  - 2023 Apr 1
TI  - Occupational respiratory allergy to reactive dyes.
PG  - 70-75
LID - 10.1097/ACI.0000000000000885 [doi]
AB  - PURPOSE OF REVIEW: Reactive dyes have been shown to cause respiratory 
      sensitization in workers with occupational exposure. The present review analyzes 
      the current knowledge of the role of reactive dyes in promoting occupational 
      respiratory allergy. We discuss the current classification of reactive dyes as 
      well as the potential development of occupational respiratory diseases after 
      exposure to these substances. RECENT FINDINGS: Few descriptions of the role of 
      reactive dyes in the development of occupational allergy have been published in 
      recent years. Several reactive dyes are considered causes of occupational asthma 
      (OA), mainly in workers in textile industries. Positive skin tests and the 
      presence of specific serum IgE antibodies to reactive dyes suggest that 
      respiratory symptoms provoked by reactive dyes may be immunoglobulin E 
      (IgE)-mediated reactions. It was suggested that airborne dye molecules may act as 
      haptens and induce IgE-mediated hypersensitivity reactions. SUMMARY: Reactive 
      dyes are widely used in the textile industry, owing to their ability to produce 
      strong covalent bonds to textile fibers. These substances have been identified as 
      potential respiratory sensitizers causing OA and occupational rhinitis. The 
      clinical presentation and phenotype of patients with OA due to reactive dyes is 
      very similar to those presented by patients with OA to high molecular weight 
      agents. The extensive use of reactive dyes in industry means that it is 
      particularly important to describe their implications for health, which in fact 
      are probably underestimated.
CI  - Copyright (c) 2022 Wolters Kluwer Health, Inc. All rights reserved.
FAU - Munoz, Xavier
AU  - Munoz X
AD  - Servicio de Neumologia. Hospital Universitario Vall d'Hebron, Barcelona.
AD  - CIBER de Enfermedades Respiratorias (CIBERES).
AD  - Department of Cell Biology, Physiology and Immunology, Autonomous University of 
      Barcelona, Barcelona, Spain.
FAU - Clofent, David
AU  - Clofent D
AD  - Servicio de Neumologia. Hospital Universitario Vall d'Hebron, Barcelona.
AD  - CIBER de Enfermedades Respiratorias (CIBERES).
FAU - Cruz, Maria-Jesus
AU  - Cruz MJ
AD  - Servicio de Neumologia. Hospital Universitario Vall d'Hebron, Barcelona.
AD  - CIBER de Enfermedades Respiratorias (CIBERES).
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20221206
PL  - United States
TA  - Curr Opin Allergy Clin Immunol
JT  - Current opinion in allergy and clinical immunology
JID - 100936359
RN  - 0 (Coloring Agents)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Humans
MH  - Coloring Agents/adverse effects
MH  - *Occupational Diseases
MH  - *Asthma, Occupational
MH  - *Occupational Exposure
MH  - Immunoglobulin E
MH  - Skin Tests/adverse effects
EDAT- 2022/12/07 06:00
MHDA- 2023/03/03 06:00
CRDT- 2022/12/06 13:43
PHST- 2022/12/07 06:00 [pubmed]
PHST- 2023/03/03 06:00 [medline]
PHST- 2022/12/06 13:43 [entrez]
AID - 00130832-202304000-00003 [pii]
AID - 10.1097/ACI.0000000000000885 [doi]
PST - ppublish
SO  - Curr Opin Allergy Clin Immunol. 2023 Apr 1;23(2):70-75. doi: 
      10.1097/ACI.0000000000000885. Epub 2022 Dec 6.