PMID- 36483026
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20221210
IS  - 2234-943X (Print)
IS  - 2234-943X (Electronic)
IS  - 2234-943X (Linking)
VI  - 12
DP  - 2022
TI  - Giant desmoplastic small round cell tumor of the abdomen: A case report.
PG  - 992346
LID - 10.3389/fonc.2022.992346 [doi]
LID - 992346
AB  - BACKGROUND: Desmoplastic small round cell tumor (DSRCT) is a rare, aggressive, 
      mesenchymal malignancy of a separate clinicopathological entity. It has a 
      predilection for young men, with no evidence of any ethnic predilection. The 
      current diagnostic gold standard for DSRCT includes histopathologic, 
      immunohistochemical, and cytogenetic studies in order to confirm the variable 
      phenotypic expression and characteristic chromosomal translocation. CASE SUMMARY: 
      A 65-year-old man presented with a sensation of an abdominal mass and a 
      presentation of an incomplete bowel obstruction. Initial lab tests were in the 
      normal range except for carbohydrate antigen. Contrast-enhanced CT showed that a 
      large, mass-confounding density was occupied in the omentum majus area of the 
      middle and lower abdominal wall. A 3D reconstruction of the images was performed 
      to clarify the relationship between the tumor and the colon and was confirmed by 
      a colonoscopy. After surgery, immunohistochemistry and fluorescence in situ 
      hybridization (FISH) revealed EWSR1-WT1 gene rearrangement at 22q12, confirming 
      the diagnosis of desmoplastic small round cell tumor. CONCLUSION: Being different 
      from the predilection of DSRCT for young men, the patient in our case is a 
      65-year-old man with a huge mass involving the transverse colon and the bladder.
CI  - Copyright (c) 2022 Wang, Chen, Wang and Su.
FAU - Wang, Wuke
AU  - Wang W
AD  - Department of General Surgery, Hwa Mei Hospital, University of Chinese Academy of 
      Sciences, Ningbo No. 2 Hospital, Ningbo, China.
FAU - Chen, Yunjie
AU  - Chen Y
AD  - Department of General Surgery, Hwa Mei Hospital, University of Chinese Academy of 
      Sciences, Ningbo No. 2 Hospital, Ningbo, China.
FAU - Wang, Chunnian
AU  - Wang C
AD  - Department of Gastrointestinal Pathology, Ningbo Diagnostic Pathology Center, 
      Ningbo, China.
FAU - Su, Hui
AU  - Su H
AD  - Department of General Surgery, Hwa Mei Hospital, University of Chinese Academy of 
      Sciences, Ningbo No. 2 Hospital, Ningbo, China.
AD  - Department of Gastrointestinal Surgery, First Affiliated Hospital of Jinan 
      University, Guangzhou, China.
LA  - eng
PT  - Case Reports
DEP - 20221122
PL  - Switzerland
TA  - Front Oncol
JT  - Frontiers in oncology
JID - 101568867
PMC - PMC9723381
OTO - NOTNLM
OT  - DSRCT
OT  - abdominopelvic tumor
OT  - case report
OT  - desmoplastic small round cell tumor
OT  - medium-elderly male
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2022/12/10 06:00
MHDA- 2022/12/10 06:01
PMCR- 2022/01/01
CRDT- 2022/12/09 03:53
PHST- 2022/07/12 00:00 [received]
PHST- 2022/10/03 00:00 [accepted]
PHST- 2022/12/09 03:53 [entrez]
PHST- 2022/12/10 06:00 [pubmed]
PHST- 2022/12/10 06:01 [medline]
PHST- 2022/01/01 00:00 [pmc-release]
AID - 10.3389/fonc.2022.992346 [doi]
PST - epublish
SO  - Front Oncol. 2022 Nov 22;12:992346. doi: 10.3389/fonc.2022.992346. eCollection 
      2022.