PMID- 36495791
OWN - NLM
STAT- MEDLINE
DCOM- 20221220
LR  - 20230111
IS  - 1878-9307 (Electronic)
IS  - 1878-9293 (Print)
IS  - 1878-9293 (Linking)
VI  - 58
DP  - 2022 Dec
TI  - Puberty contributes to adolescent development of fronto-striatal functional 
      connectivity supporting inhibitory control.
PG  - 101183
LID - S1878-9293(22)00126-8 [pii]
LID - 10.1016/j.dcn.2022.101183 [doi]
LID - 101183
AB  - Adolescence is defined by puberty and represents a period characterized by neural 
      circuitry maturation (e.g., fronto-striatal systems) facilitating cognitive 
      improvements. Though studies have characterized age-related changes, the extent 
      to which puberty influences maturation of fronto-striatal networks is less known. 
      Here, we combine two longitudinal datasets to characterize the role of puberty in 
      the development of fronto-striatal resting-state functional connectivity (rsFC) 
      and its relationship to inhibitory control in 106 10-18-year-olds. Beyond age 
      effects, we found that puberty was related to decreases in rsFC between the 
      caudate and the anterior vmPFC, rostral and ventral ACC, and v/dlPFC, as well as 
      with rsFC increases between the dlPFC and nucleus accumbens (NAcc) across males 
      and females. Stronger caudate rsFC with the dlPFC and vlPFC during early puberty 
      was associated with worse inhibitory control and slower correct responses, 
      respectively, whereas by late puberty, stronger vlPFC rsFC with the dorsal 
      striatum was associated with faster correct responses. Taken together, our 
      findings suggest that certain fronto-striatal connections are associated with 
      pubertal maturation beyond age effects, which, in turn are related to inhibitory 
      control. We discuss implications of puberty-related fronto-striatal maturation to 
      further our understanding of pubertal effects related to adolescent cognitive and 
      affective neurodevelopment.
CI  - Copyright (c) 2022 The Authors. Published by Elsevier Ltd.. All rights reserved.
FAU - Ojha, Amar
AU  - Ojha A
AD  - Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA; Center 
      for the Neural Basis of Cognition, University of Pittsburgh, Pittsburgh, PA, USA. 
      Electronic address: amo80@pitt.edu.
FAU - Parr, Ashley C
AU  - Parr AC
AD  - Center for the Neural Basis of Cognition, University of Pittsburgh, Pittsburgh, 
      PA, USA; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
FAU - Foran, William
AU  - Foran W
AD  - Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
FAU - Calabro, Finnegan J
AU  - Calabro FJ
AD  - Center for the Neural Basis of Cognition, University of Pittsburgh, Pittsburgh, 
      PA, USA; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA; 
      Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA.
FAU - Luna, Beatriz
AU  - Luna B
AD  - Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA; Center 
      for the Neural Basis of Cognition, University of Pittsburgh, Pittsburgh, PA, USA; 
      Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA; 
      Department of Psychology, University of Pittsburgh, Pittsburgh, PA, USA.
LA  - eng
GR  - T32 GM081760/GM/NIGMS NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
DEP - 20221129
PL  - Netherlands
TA  - Dev Cogn Neurosci
JT  - Developmental cognitive neuroscience
JID - 101541838
SB  - IM
MH  - Adolescent
MH  - Male
MH  - Female
MH  - Humans
MH  - *Adolescent Development
MH  - *Magnetic Resonance Imaging
MH  - Corpus Striatum
MH  - Puberty/physiology
MH  - Nucleus Accumbens/physiology
PMC - PMC9730138
OTO - NOTNLM
OT  - Adolescence
OT  - Inhibitory control
OT  - Puberty
OT  - Resting-state functional connectivity
COIS- Declaration of Competing Interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2022/12/11 06:00
MHDA- 2022/12/21 06:00
PMCR- 2022/11/29
CRDT- 2022/12/10 18:28
PHST- 2022/04/30 00:00 [received]
PHST- 2022/09/06 00:00 [revised]
PHST- 2022/11/28 00:00 [accepted]
PHST- 2022/12/11 06:00 [pubmed]
PHST- 2022/12/21 06:00 [medline]
PHST- 2022/12/10 18:28 [entrez]
PHST- 2022/11/29 00:00 [pmc-release]
AID - S1878-9293(22)00126-8 [pii]
AID - 101183 [pii]
AID - 10.1016/j.dcn.2022.101183 [doi]
PST - ppublish
SO  - Dev Cogn Neurosci. 2022 Dec;58:101183. doi: 10.1016/j.dcn.2022.101183. Epub 2022 
      Nov 29.