PMID- 36496701 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20221221 IS - 2304-8158 (Print) IS - 2304-8158 (Electronic) IS - 2304-8158 (Linking) VI - 11 IP - 23 DP - 2022 Dec 2 TI - Maternal Diet Quality and the Health Status of Newborns. LID - 10.3390/foods11233893 [doi] LID - 3893 AB - The maternal diet during pregnancy affects neonatal health status. The objective of this study was to assess the nutritional quality of the maternal diet, and its contamination by persistent organic pollutants (POPs), in pregnant women living in two areas of the Czech Republic with different levels of air pollution, and subsequently to assess the relationship of these two factors with birth weight and neonatal oxidative stress. To determine the level of oxidative stress, 8-isoprostane concentrations in umbilical cord plasma were measured. The overall nutritional quality of the maternal diet was not optimal. Of the nutritional factors, protein intake proved to be the most significant showing a positive relationship with birth weight, and a negative relationship with the oxidative stress of newborns. Dietary contamination by persistent organic pollutants was low and showed no statistically significant relationship with birth weight. Only one of the 67 analyzed POPs, namely the insecticide dichlorodiphenyltrichloroethane (DDT), showed a statistically significant positive relationship with the level of neonatal oxidative stress. FAU - Pavlikova, Jitka AU - Pavlikova J AD - Institute of Experimental Medicine AS CR, Department of Genetic Toxicology and Epigenetics, Videnska 1083, 142 20 Prague, Czech Republic. FAU - Ambroz, Antonin AU - Ambroz A AD - Institute of Experimental Medicine AS CR, Department of Nanotoxicology and Molecular Epidemiology, Videnska 1083, 142 20 Prague, Czech Republic. FAU - Honkova, Katerina AU - Honkova K AUID- ORCID: 0000-0002-5713-8161 AD - Institute of Experimental Medicine AS CR, Department of Genetic Toxicology and Epigenetics, Videnska 1083, 142 20 Prague, Czech Republic. FAU - Chvojkova, Irena AU - Chvojkova I AD - Institute of Experimental Medicine AS CR, Department of Genetic Toxicology and Epigenetics, Videnska 1083, 142 20 Prague, Czech Republic. FAU - Sram, Radim J AU - Sram RJ AUID- ORCID: 0000-0002-2500-4572 AD - Institute of Experimental Medicine AS CR, Department of Genetic Toxicology and Epigenetics, Videnska 1083, 142 20 Prague, Czech Republic. FAU - Rossner, Pavel Jr AU - Rossner P Jr AUID- ORCID: 0000-0001-6921-5446 AD - Institute of Experimental Medicine AS CR, Department of Nanotoxicology and Molecular Epidemiology, Videnska 1083, 142 20 Prague, Czech Republic. FAU - Topinka, Jan AU - Topinka J AD - Institute of Experimental Medicine AS CR, Department of Genetic Toxicology and Epigenetics, Videnska 1083, 142 20 Prague, Czech Republic. FAU - Gramblicka, Tomas AU - Gramblicka T AD - Department of Food Analysis and Nutrition, Faculty of Food and Biochemical Technology, University of Chemistry and Technology, Technicka 3, 166 28 Prague, Czech Republic. FAU - Parizek, Ondrej AU - Parizek O AD - Department of Food Analysis and Nutrition, Faculty of Food and Biochemical Technology, University of Chemistry and Technology, Technicka 3, 166 28 Prague, Czech Republic. FAU - Parizkova, Denisa AU - Parizkova D AD - Department of Food Analysis and Nutrition, Faculty of Food and Biochemical Technology, University of Chemistry and Technology, Technicka 3, 166 28 Prague, Czech Republic. FAU - Schmuczerova, Jana AU - Schmuczerova J AD - Department of Medical Genetics, L. Pasteur University Hospital, Trieda SNP 1, 040 11 Kosice, Slovakia. FAU - Pulkrabova, Jana AU - Pulkrabova J AUID- ORCID: 0000-0003-1965-4672 AD - Department of Food Analysis and Nutrition, Faculty of Food and Biochemical Technology, University of Chemistry and Technology, Technicka 3, 166 28 Prague, Czech Republic. FAU - Rossnerova, Andrea AU - Rossnerova A AD - Institute of Experimental Medicine AS CR, Department of Genetic Toxicology and Epigenetics, Videnska 1083, 142 20 Prague, Czech Republic. LA - eng GR - the Research Infrastructure NanoEnviCZ, LM2018124/Ministry of Education, Youth and Sports of the Czech Republic/ GR - the Research Infrastructure EATRIS-CZ, LM2018133/Ministry of Education, Youth and Sports of the Czech Republic/ GR - project Pro-NanoEnviCz (Project No. CZ.02.1.01/0.0/0.0/16_013/0001821)/European Union - European Structural and Investments Funds in the frame of Operational Programme Research Development and Education/ PT - Journal Article DEP - 20221202 PL - Switzerland TA - Foods JT - Foods (Basel, Switzerland) JID - 101670569 PMC - PMC9739031 OTO - NOTNLM OT - 8-isoprostane OT - DDT OT - birth weight OT - maternal diet quality OT - maternal protein intake OT - oxidative stress OT - persistent organic pollutants COIS- The authors declare no conflict of interest. EDAT- 2022/12/12 06:00 MHDA- 2022/12/12 06:01 PMCR- 2022/12/02 CRDT- 2022/12/11 01:01 PHST- 2022/09/17 00:00 [received] PHST- 2022/11/12 00:00 [revised] PHST- 2022/11/30 00:00 [accepted] PHST- 2022/12/11 01:01 [entrez] PHST- 2022/12/12 06:00 [pubmed] PHST- 2022/12/12 06:01 [medline] PHST- 2022/12/02 00:00 [pmc-release] AID - foods11233893 [pii] AID - foods-11-03893 [pii] AID - 10.3390/foods11233893 [doi] PST - epublish SO - Foods. 2022 Dec 2;11(23):3893. doi: 10.3390/foods11233893.