PMID- 36496702
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20221222
IS  - 2304-8158 (Print)
IS  - 2304-8158 (Electronic)
IS  - 2304-8158 (Linking)
VI  - 11
IP  - 23
DP  - 2022 Dec 2
TI  - Separation and Detection of Abamectin, Ivermectin, Albendazole and Three 
      Metabolites in Eggs Using Reversed-Phase HPLC Coupled with a Photo Diode Array 
      Detector.
LID - 10.3390/foods11233894 [doi]
LID - 3894
AB  - An innovative and sensitive approach using high-performance liquid 
      chromatography-photo diode array detection (HPLC-PDAD) was developed and 
      optimized for the simultaneous determination of abamectin (ABM), ivermectin 
      (IVM), albendazole (ABZ) and three metabolites in eggs. The samples were 
      extracted with acetonitrile (MeCN)/water (90:10, v/v), and the extracts 
      containing the targets were cleaned up and concentrated by a series of 
      liquid-liquid extraction (LLE) steps. A reversed-phase C18 column and a mobile 
      phase consisting of 0.1% trifluoroacetic acid (TFA) aqueous solution and methanol 
      (MeOH) were utilized to perform optimal chromatographic separation. The developed 
      method was validated on the basis of international guidelines. The limits of 
      detection (LODs) and quantitation (LOQs) were 2.1-10.5 microg/kg and 7.8-28.4 microg/kg, 
      respectively. Satisfactory linear relationships were observed for the targets in 
      their corresponding concentration ranges. The mean recoveries ranged from 85.7% 
      to 97.21% at 4 addition levels, with intraday and interday relative standard 
      deviations (RSDs) in the ranges of 1.68-4.77% and 1.74-5.31%, respectively. The 
      presented protocol was demonstrated to be applicable and reliable by being 
      applied for the detection of target residues in locally sourced egg samples.
FAU - Guo, Yawen
AU  - Guo Y
AD  - College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, 
      China.
AD  - Joint International Research Laboratory of Agriculture & Agri-Product Safety, 
      Yangzhou University, Yangzhou 225009, China.
FAU - He, Zhaoyuan
AU  - He Z
AD  - College of Animal Science and Technology, Guangxi University, Nanning 530000, 
      China.
FAU - Zhu, Yali
AU  - Zhu Y
AD  - College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, 
      China.
AD  - Joint International Research Laboratory of Agriculture & Agri-Product Safety, 
      Yangzhou University, Yangzhou 225009, China.
FAU - Liu, Shuyu
AU  - Liu S
AD  - College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, 
      China.
AD  - Joint International Research Laboratory of Agriculture & Agri-Product Safety, 
      Yangzhou University, Yangzhou 225009, China.
FAU - Gao, Pengfei
AU  - Gao P
AD  - College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, 
      China.
AD  - Joint International Research Laboratory of Agriculture & Agri-Product Safety, 
      Yangzhou University, Yangzhou 225009, China.
FAU - Xie, Kaizhou
AU  - Xie K
AD  - College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, 
      China.
AD  - Joint International Research Laboratory of Agriculture & Agri-Product Safety, 
      Yangzhou University, Yangzhou 225009, China.
FAU - Zhang, Tao
AU  - Zhang T
AUID- ORCID: 0000-0003-1170-1622
AD  - College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, 
      China.
AD  - Joint International Research Laboratory of Agriculture & Agri-Product Safety, 
      Yangzhou University, Yangzhou 225009, China.
FAU - Dong, Yuhao
AU  - Dong Y
AD  - College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, 
      China.
LA  - eng
GR  - CARS-41/the earmarked fund for the China Agriculture Research System/
GR  - PAPD/the Priority Academic Program Development of Jiangsu Higher Education 
      Institutions/
GR  - Not applicable/the Yangzhou University High-end Talent Support Program/
GR  - KYCX22_3526/the Postgraduate Research and Practice Innovation Program of Jiangsu 
      Province/
PT  - Journal Article
DEP - 20221202
PL  - Switzerland
TA  - Foods
JT  - Foods (Basel, Switzerland)
JID - 101670569
PMC - PMC9741328
OTO - NOTNLM
OT  - HPLC-PDAD
OT  - LLE
OT  - abamectin
OT  - albendazole
OT  - ivermectin
COIS- The authors declare no conflict of interest.
EDAT- 2022/12/12 06:00
MHDA- 2022/12/12 06:01
PMCR- 2022/12/02
CRDT- 2022/12/11 01:01
PHST- 2022/11/02 00:00 [received]
PHST- 2022/11/24 00:00 [revised]
PHST- 2022/11/28 00:00 [accepted]
PHST- 2022/12/11 01:01 [entrez]
PHST- 2022/12/12 06:00 [pubmed]
PHST- 2022/12/12 06:01 [medline]
PHST- 2022/12/02 00:00 [pmc-release]
AID - foods11233894 [pii]
AID - foods-11-03894 [pii]
AID - 10.3390/foods11233894 [doi]
PST - epublish
SO  - Foods. 2022 Dec 2;11(23):3894. doi: 10.3390/foods11233894.