PMID- 36504589
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20221220
IS  - 2213-8803 (Electronic)
IS  - 2213-879X (Print)
IS  - 2213-879X (Linking)
VI  - 10
IP  - 3
DP  - 2022 Jul-Sep
TI  - Dendritic Cell-Based Immunotherapies and their Potential use in Colorectal Cancer 
      Immunotherapy.
PG  - 107-113
LID - 10.4103/jmau.jmau_20_21 [doi]
AB  - Dendritic cells (DCs) are professional antigen-presenting cells, which are 
      resident or proliferating in organs. Major histocompatibility complex (MHC) Class 
      I and II on DCs in normal steady conditions process and present antigens 
      including cancer antigens. Many approaches are used to enhance antigen 
      presentation process of DCs and capture cancer cells. DCs are harvested from 
      cancer patients and manipulated ex vivo in DC-based cancer immunotherapy. In 
      addition, DCs' vaccines and other anticancer therapy combinations were discussed 
      to optimize DCs' efficiency for cancer immunotherapy. This review addressed the 
      use of the human conventional type-1 DCs, OX40(+) plasmacytoid DCs, and 
      DCs-derived exosomes. In addition, different combinations with DCs therapy such 
      as combination with the monoclonal antibody, cytokine-induced killer cells, 
      adjuvants, chemotherapy (DCs-based chemoimmunotherapy), and nanoparticles were 
      listed and explored for their effectiveness against cancer, and mainly against 
      colorectal cancer.
CI  - Copyright: (c) 2021 Journal of Microscopy and Ultrastructure.
FAU - Aldahlawi, Alia M
AU  - Aldahlawi AM
AD  - Department of Biological Sciences, Faculty of Science, King Abdulaziz University, 
      Jeddah, Saudi Arabia.
AD  - Immunology Unit, King Fahad Medical Research Center, King Abdulaziz University, 
      Jeddah, Saudi Arabia.
FAU - Abdullah, Samaa Taha
AU  - Abdullah ST
AD  - Department of Biological Sciences, Faculty of Science, King Abdulaziz University, 
      Jeddah, Saudi Arabia.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20210709
PL  - India
TA  - J Microsc Ultrastruct
JT  - Journal of microscopy and ultrastructure
JID - 101709862
PMC - PMC9728090
OTO - NOTNLM
OT  - Adjuvants
OT  - OX40+ plasmacytoid dendritic cells
OT  - colorectal cancer
OT  - cytokine-induced killer cells
OT  - dendritic cells
OT  - dendritic cells-based chemoimmunotherapy
OT  - exosomes
OT  - nanoparticles-dendritic cells immunotherapy
COIS- There are no conflicts of interest.
EDAT- 2021/07/09 00:00
MHDA- 2021/07/09 00:01
PMCR- 2021/07/09
CRDT- 2022/12/12 10:44
PHST- 2021/02/15 00:00 [received]
PHST- 2021/04/14 00:00 [revised]
PHST- 2021/04/17 00:00 [accepted]
PHST- 2022/12/12 10:44 [entrez]
PHST- 2021/07/09 00:00 [pubmed]
PHST- 2021/07/09 00:01 [medline]
PHST- 2021/07/09 00:00 [pmc-release]
AID - JMAU-10-107 [pii]
AID - 10.4103/jmau.jmau_20_21 [doi]
PST - epublish
SO  - J Microsc Ultrastruct. 2021 Jul 9;10(3):107-113. doi: 10.4103/jmau.jmau_20_21. 
      eCollection 2022 Jul-Sep.