PMID- 36507507
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20221221
IS  - 2296-858X (Print)
IS  - 2296-858X (Electronic)
IS  - 2296-858X (Linking)
VI  - 9
DP  - 2022
TI  - Patterns of participation restriction among older adults at risk of falls and 
      relationship with intrinsic capacity: A latent cluster analysis.
PG  - 1023879
LID - 10.3389/fmed.2022.1023879 [doi]
LID - 1023879
AB  - INTRODUCTION: The concept of participation restriction was first described by the 
      World Health Organization in 2001 as a component of The International 
      Classification of Functioning, Disability and Health Framework. Both falls and 
      fear of falling (FOF) are associated with social isolation, depression, anxiety, 
      poor quality of life and cognitive impairment resulting in participation 
      restriction. Life-space mobility (LSM) is an important indicator for 
      participation restriction which depends on multiple inter-related factors. We 
      aimed to determine participation patterns using latent cluster analysis (LCA) in 
      older adults at risk of falls, its relationship with intrinsic capacity (IC) and 
      its risk prediction. METHODS: Cross-sectional study of 154 community dwelling 
      older adults >/= 60 years with falls or risk of falls was conducted. Questionnaires 
      were administered on demographics, hearing, LSM, frailty (FRAIL scale), anorexia 
      of aging (SNAQ), cognition (Montreal Cognitive Assessment, MoCA), FOF (Falls 
      Efficacy Scale-International), physical function, and assessment for handgrip 
      strength (HGS), gait speed, 5-times sit to stand (STS), vision and 
      times-up-and-go (TUG) were performed. Six IC domains (vision and hearing, 
      cognition, nutrition, mobility and depression) were measured. RESULTS: Three 
      pattern of participation cluster were identified, high (n = 63, 40.9%), moderate 
      (n = 83, 53.9%) and low (n = 8, 33 5.2%). Individuals in the high participation 
      cluster were significantly younger, had higher LSM scores and lower FES-I scores, 
      more robust, fewer ADL and IADL limitations, lower prevalence of low HGS, higher 
      gait speed and shorter TUG. In the fully adjusted model compared to the high 
      participation cluster, moderate participation was significantly associated with 
      low MoCA scores (OR 4.2, 95% CI 1.7-10.4, p = 0.02), poor STS (OR 7.1, 95% CI 
      3.0-17.0, p < 0.001) whereas low participation was associated with anorexia of 
      aging (OR 9.9, 95% CI 1.6-60.9, p = 0.014), poor STS (OR 19.1, 95% CI 2.0-187.5, 
      p = 0.011) and hearing impairment (OR 9.8, 95% CI 1.4-70.8, p = 0.024). 
      Participants with 3 out of 6 IC decline had a probability of greater than 80% to 
      belong to the low/moderate participation class. DISCUSSION: Physical function, 
      cognition, hearing and nutrition were significantly associated with low and/or 
      moderate participation class. Future studies are needed to evaluate improvement 
      in participation of those with falls or at risk for falls through restoration of 
      IC.
CI  - Copyright (c) 2022 Merchant, Chan, Aprahamian and Morley.
FAU - Merchant, Reshma Aziz
AU  - Merchant RA
AD  - Division of Geriatric Medicine, Department of Medicine, National University 
      Hospital, Singapore, Singapore.
AD  - Department of Medicine, Yong Loo Lin School of Medicine, National University of 
      Singapore, Singapore, Singapore.
FAU - Chan, Yiong Huak
AU  - Chan YH
AD  - Biostatistics Unit, Yong Loo Lin School of Medicine, National University of 
      Singapore, Singapore, Singapore.
FAU - Aprahamian, Ivan
AU  - Aprahamian I
AD  - Geriatrics Division, Department of Internal Medicine, Jundiai Medical School, 
      Jundiai, Sao Paulo, Brazil.
FAU - Morley, John E
AU  - Morley JE
AD  - Division of Geriatric Medicine, Department of Medicine, Saint Louis University 
      School of Medicine, St. Louis, MO, United States.
LA  - eng
PT  - Journal Article
DEP - 20221125
PL  - Switzerland
TA  - Front Med (Lausanne)
JT  - Frontiers in medicine
JID - 101648047
PMC - PMC9732451
OTO - NOTNLM
OT  - falls
OT  - intrinsic capacity
OT  - latent class analysis
OT  - life-space mobility
OT  - participation restriction
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2022/12/13 06:00
MHDA- 2022/12/13 06:01
PMCR- 2022/11/25
CRDT- 2022/12/12 11:38
PHST- 2022/08/20 00:00 [received]
PHST- 2022/10/26 00:00 [accepted]
PHST- 2022/12/12 11:38 [entrez]
PHST- 2022/12/13 06:00 [pubmed]
PHST- 2022/12/13 06:01 [medline]
PHST- 2022/11/25 00:00 [pmc-release]
AID - 10.3389/fmed.2022.1023879 [doi]
PST - epublish
SO  - Front Med (Lausanne). 2022 Nov 25;9:1023879. doi: 10.3389/fmed.2022.1023879. 
      eCollection 2022.