PMID- 3651621 OWN - NLM STAT- MEDLINE DCOM- 19871116 LR - 20191030 IS - 0303-6847 (Print) IS - 0303-6847 (Linking) VI - 24 IP - 6 DP - 1987 TI - Noradrenaline content and release in the mesenteric artery of stroke-prone spontaneously hypertensive rats (SHRSP) and a new strain of SHRSP (M-SHRSP). PG - 334-8 AB - Adrenergic innervation in the main trunk of the mesenteric artery was studied in stroke-prone spontaneously hypertensive rats (SHRSP) as well as in a new strain of SHRSP (M-SHRSP) and was compared with that of normotensive Wistar Kyoto rats (WKY). Noradrenaline (NA) content and high K-induced NA release in the artery of 6-week-old SHRSP and M-SHRSP were greater than those in the artery of WKY. These results suggest that a higher adrenergic innervation of the artery might be involved in the development of hypertension in SHRSP and M-SHRSP. FAU - Shimamura, K AU - Shimamura K AD - Research Institute of Hypertension, Kinki University, Osaka, Japan. FAU - Shimada, T AU - Shimada T FAU - Yamamoto, K AU - Yamamoto K FAU - Sunano, S AU - Sunano S FAU - Okamoto, K AU - Okamoto K LA - eng PT - Comparative Study PT - Journal Article PL - Switzerland TA - Blood Vessels JT - Blood vessels JID - 0427130 RN - 9NEZ333N27 (Sodium) RN - RWP5GA015D (Potassium) RN - X4W3ENH1CV (Norepinephrine) SB - IM MH - Animals MH - Cerebrovascular Disorders/*metabolism MH - Disease Susceptibility MH - Hypertension/*metabolism MH - Male MH - Mesenteric Arteries/drug effects/*metabolism MH - Norepinephrine/*metabolism MH - Potassium/pharmacology MH - Rats MH - Rats, Inbred SHR/metabolism MH - Rats, Inbred Strains/*metabolism MH - Rats, Inbred WKY/metabolism MH - Rats, Mutant Strains/*metabolism MH - Sodium/metabolism EDAT- 1987/01/01 00:00 MHDA- 1987/01/01 00:01 CRDT- 1987/01/01 00:00 PHST- 1987/01/01 00:00 [pubmed] PHST- 1987/01/01 00:01 [medline] PHST- 1987/01/01 00:00 [entrez] AID - 10.1159/000158710 [doi] PST - ppublish SO - Blood Vessels. 1987;24(6):334-8. doi: 10.1159/000158710.