PMID- 36517067
OWN - NLM
STAT- MEDLINE
DCOM- 20221216
LR  - 20231216
IS  - 1658-3175 (Electronic)
IS  - 0379-5284 (Print)
IS  - 0379-5284 (Linking)
VI  - 43
IP  - 12
DP  - 2022 Dec
TI  - Endobronchial valve therapy for patients with advanced emphysema. A report from a 
      tertiary care center in China.
PG  - 1397-1401
LID - 10.15537/smj.2022.43.12.20220527 [doi]
AB  - OBJECTIVES: To assess the efficiency and safety of endobronchial valve (EBV) 
      treatment in Chinese patients. METHODS: A retrospective analysis was performed in 
      patients with chronic obstructive pulmonary disease who underwent EBV 
      implantation in our hospital between October 2010 and January 2017. All patients 
      were confirmed with no collateral ventilation (CV-) or with low airflow (LF) in 
      the treated lobe. Pulmonary function parameters, the 6-minute walk distance 
      (6MWD), the modified Medical Research Council (mMRC), as well as adverse events 
      in the follow-up period were recorded. RESULTS: Thirty-eight advanced emphysema 
      patients received EBV implantation. Significant improvements were found in forced 
      expiratory volume in 1 second (FEV(1))(FEV(1): +0.12 L), 6MWD (+64.9 m), and mMRC 
      (-0.5 points). A total of 55.3% and 65.8% of subjects met the score for the 
      minimal clinically important difference in FEV(1) and 6MWD, respectively. FEV(1) 
      improved more significantly in the CV- group than in the LF group. Pneumothorax 
      or death did not occur during the follow-up period. CONCLUSION: Endobronchial 
      valve treatment in patients with advanced emphysema and CV- provides clinically 
      meaningful benefits with a low incidence of pneumothorax. The efficiency and 
      safety of EBV therapy are acceptable in China.
CI  - Copyright: (c) Saudi Medical Journal.
FAU - Yu, Hang
AU  - Yu H
AD  - From the Senior Department of Respiratory and Critical Care Medicine, the Eighth 
      Medical Center, Chinese PLA General Hospital, Beijing, China.
FAU - Yang, Zhen
AU  - Yang Z
AD  - From the Senior Department of Respiratory and Critical Care Medicine, the Eighth 
      Medical Center, Chinese PLA General Hospital, Beijing, China.
FAU - Zhu, Minghui
AU  - Zhu M
AD  - From the Senior Department of Respiratory and Critical Care Medicine, the Eighth 
      Medical Center, Chinese PLA General Hospital, Beijing, China.
FAU - Liang, Zhixin
AU  - Liang Z
AD  - From the Senior Department of Respiratory and Critical Care Medicine, the Eighth 
      Medical Center, Chinese PLA General Hospital, Beijing, China.
FAU - Zhao, Wei
AU  - Zhao W
AD  - From the Senior Department of Respiratory and Critical Care Medicine, the Eighth 
      Medical Center, Chinese PLA General Hospital, Beijing, China.
FAU - Zhu, Qiang
AU  - Zhu Q
AD  - From the Senior Department of Respiratory and Critical Care Medicine, the Eighth 
      Medical Center, Chinese PLA General Hospital, Beijing, China.
FAU - Chen, Liang-An
AU  - Chen LA
AD  - From the Senior Department of Respiratory and Critical Care Medicine, the Eighth 
      Medical Center, Chinese PLA General Hospital, Beijing, China.
LA  - eng
PT  - Journal Article
PL  - Saudi Arabia
TA  - Saudi Med J
JT  - Saudi medical journal
JID - 7909441
SB  - IM
MH  - Humans
MH  - *Pneumothorax
MH  - Tertiary Care Centers
MH  - Retrospective Studies
MH  - Bronchoscopy
MH  - *Pulmonary Emphysema/surgery/complications
MH  - *Emphysema/complications
MH  - Forced Expiratory Volume
MH  - Treatment Outcome
PMC - PMC9994510
OTO - NOTNLM
OT  - bronchoscopic lung volume reduction
OT  - emphysema
OT  - endobronchial valve
EDAT- 2022/12/15 06:00
MHDA- 2022/12/17 06:00
PMCR- 2022/12/01
CRDT- 2022/12/14 20:43
PHST- 2022/07/17 00:00 [received]
PHST- 2022/10/20 00:00 [accepted]
PHST- 2022/12/14 20:43 [entrez]
PHST- 2022/12/15 06:00 [pubmed]
PHST- 2022/12/17 06:00 [medline]
PHST- 2022/12/01 00:00 [pmc-release]
AID - 43/12/1397 [pii]
AID - SaudiMedJ-43-12-1397 [pii]
AID - 10.15537/smj.2022.43.12.20220527 [doi]
PST - ppublish
SO  - Saudi Med J. 2022 Dec;43(12):1397-1401. doi: 10.15537/smj.2022.43.12.20220527.