PMID- 36518179 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20221221 IS - 2052-8817 (Electronic) IS - 2052-8817 (Linking) VI - 9 IP - 1 DP - 2022 Jan-Dec TI - Pump-controlled retrograde trial off for weaning from venoarterial extracorporeal membrane oxygenation in an adult patient with pulmonary embolism. PG - e809 LID - 10.1002/ams2.809 [doi] LID - e809 AB - BACKGROUND: Although pump-controlled retrograde trial off (PCRTO) is a practical method for weaning from venoarterial extracorporeal membrane oxygenation (VA-ECMO), its advantages and safety for patients with pulmonary embolism are not yet reported. CASE PRESENTATION: A 62-year-old man with coronavirus disease 2019 experienced sudden cardiac arrest, and VA-ECMO was introduced. After confirming a massive acute pulmonary embolism, unfractionated heparin treatment was initiated. On day 6, the patient was confirmed stable with a flow rate of 1.0 L/min. However, decannulation led to cardiac arrest and reintroduction of VA-ECMO. After further treatment, a residual thrombus was observed, and pulmonary arterial pressure remained high. On day 23, ECMO was decannulated successfully after a weaning test with PCRTO, which simulated ECMO withdrawal by generating a partial arteriovenous shunt. CONCLUSION: PCRTO is a feasible weaning strategy and can be considered for patients with uncertain cardiorespiratory recovery. CI - (c) 2022 The Authors. Acute Medicine & Surgery published by John Wiley & Sons Australia, Ltd on behalf of Japanese Association for Acute Medicine. FAU - Matsumura, Kazuki AU - Matsumura K AUID- ORCID: 0000-0001-9367-1636 AD - Department of Emergency and Critical Care Medicine, ECMO Center Tokyo Metropolitan Tama Medical Center Fuchu Tokyo Japan. AD - Department of Emergency and Critical Care Medicine Keio University School of Medicine Shinjuku Tokyo Japan. FAU - Matsuyoshi, Takeo AU - Matsuyoshi T AUID- ORCID: 0000-0003-0597-5061 AD - Department of Emergency and Critical Care Medicine, ECMO Center Tokyo Metropolitan Tama Medical Center Fuchu Tokyo Japan. FAU - Horikoshi, Yuichi AU - Horikoshi Y AUID- ORCID: 0000-0002-6591-6461 AD - Department of Emergency and Critical Care Medicine, ECMO Center Tokyo Metropolitan Tama Medical Center Fuchu Tokyo Japan. FAU - Sasaki, Junichi AU - Sasaki J AUID- ORCID: 0000-0002-5190-8524 AD - Department of Emergency and Critical Care Medicine Keio University School of Medicine Shinjuku Tokyo Japan. FAU - Shimizu, Keiki AU - Shimizu K AD - Department of Emergency and Critical Care Medicine, ECMO Center Tokyo Metropolitan Tama Medical Center Fuchu Tokyo Japan. LA - eng PT - Case Reports DEP - 20221211 PL - United States TA - Acute Med Surg JT - Acute medicine & surgery JID - 101635464 PMC - PMC9741914 OTO - NOTNLM OT - COVID-19 OT - extracorporeal membrane oxygenation OT - hemodynamics OT - pulmonary embolism OT - safety EDAT- 2022/12/16 06:00 MHDA- 2022/12/16 06:01 PMCR- 2022/12/11 CRDT- 2022/12/15 02:15 PHST- 2022/07/07 00:00 [received] PHST- 2022/11/17 00:00 [accepted] PHST- 2022/12/15 02:15 [entrez] PHST- 2022/12/16 06:00 [pubmed] PHST- 2022/12/16 06:01 [medline] PHST- 2022/12/11 00:00 [pmc-release] AID - AMS2809 [pii] AID - 10.1002/ams2.809 [doi] PST - epublish SO - Acute Med Surg. 2022 Dec 11;9(1):e809. doi: 10.1002/ams2.809. eCollection 2022 Jan-Dec.