PMID- 36523539 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20221221 IS - 1687-9627 (Print) IS - 1687-9635 (Electronic) VI - 2022 DP - 2022 TI - Atypical Presentation of Kimura's Disease in a Male Patient: A Case Report and Review of Literature. PG - 5103547 LID - 10.1155/2022/5103547 [doi] LID - 5103547 AB - Kimura's disease (KD) is a rare chronic inflammatory condition of unknown aetiology. It is a benign disease that might mimic a neoplastic process. It primarily affects the head and neck region, presenting as deep subcutaneous masses, and is often accompanied by triad regional lymphadenopathy, salivary gland involvement, and high serum immunoglobulin E (IgE) levels. Here, we report the second documented case of KD in Palestine diagnosed in a 28-year-old male patient who presented with lymphadenopathy and increased serum immunoglobulin E and G (IgE and IgG) associated with intermittent abdominal pain, generalised fatigue, hepatomegaly, cardiomyopathy, reactive airway disease, peripheral vasculopathy, peripheral neuropathy, and focal segmental glomerulosclerosis. The patient was managed with steroids and an immunosuppressant (Azathioprine) with a moderate response for two years. In 2021, treatment with Mycophenolate Mofetil was initiated, which was more effective than Azathioprine. CI - Copyright (c) 2022 Zahra A. Natsha et al. FAU - Natsha, Zahra A AU - Natsha ZA AUID- ORCID: 0000-0002-1378-5543 AD - Al-Quds University Faculty of Medicine, Jerusalem, State of Palestine. FAU - Hamarsheh, Islam A AU - Hamarsheh IA AUID- ORCID: 0000-0001-6362-760X AD - Al-Quds University Faculty of Medicine, Jerusalem, State of Palestine. FAU - Utt, Rawan S AU - Utt RS AUID- ORCID: 0000-0003-4223-2777 AD - Al-Quds University Faculty of Medicine, Jerusalem, State of Palestine. FAU - Abu Alrob, Bassam AU - Abu Alrob B AD - Palestine Medical Complex, Ramallah, State of Palestine. FAU - Wahdan, Adnan A AU - Wahdan AA AD - Palestine Medical Complex, Ramallah, State of Palestine. LA - eng PT - Case Reports DEP - 20221206 PL - United States TA - Case Rep Med JT - Case reports in medicine JID - 101512910 PMC - PMC9747314 COIS- The authors declare that they have no conflicts of interest. EDAT- 2022/12/17 06:00 MHDA- 2022/12/17 06:01 PMCR- 2022/12/06 CRDT- 2022/12/16 02:21 PHST- 2022/08/29 00:00 [received] PHST- 2022/10/21 00:00 [revised] PHST- 2022/11/07 00:00 [accepted] PHST- 2022/12/16 02:21 [entrez] PHST- 2022/12/17 06:00 [pubmed] PHST- 2022/12/17 06:01 [medline] PHST- 2022/12/06 00:00 [pmc-release] AID - 10.1155/2022/5103547 [doi] PST - epublish SO - Case Rep Med. 2022 Dec 6;2022:5103547. doi: 10.1155/2022/5103547. eCollection 2022.