PMID- 36525968
OWN - NLM
STAT- In-Process
LR  - 20240424
IS  - 1531-1937 (Electronic)
IS  - 0897-1900 (Linking)
VI  - 37
IP  - 3
DP  - 2024 Jun
TI  - Assessment of Potentially Inappropriate Prescribing for People With Type 2 
      Diabetes Mellitus Using IMPACT2DM, a New Explicit Tool.
PG  - 546-556
LID - 10.1177/08971900221145219 [doi]
AB  - Background: People with type 2 diabetes mellitus (T2DM) are at greater risk of 
      potentially inappropriate prescribing (PIP) due to multiple comorbidities and 
      polypharmacy. IMPACT2DM (Inappropriate Medication Prescribing Assessment Criteria 
      for Type 2 Diabetes Mellitus) is a tool designed to identify PIP for adults with 
      T2DM. Objectives: To assess PIP for adults with T2DM in Ethiopia using the 
      IMPACT2DM and to test the face validity and clinical validity of the tool. 
      Methods: A cross-sectional study was undertaken using data extracted 
      retrospectively from the medical records of adults being managed for T2DM at 
      Debretabore Hospital. PIP was assessed using IMPACT2DM. Some items/item 
      components of IMPACT2DM were modified to increase the tool's applicability for 
      the outpatient setting, to clarify content or to use the terms most common in 
      this particular setting. Multivariant logistic regression analyses were conducted 
      to identify factors associated with PIP. Results: More than 90% of medical 
      records had at least 1 PIP. Prescribing omission (80.9%) was the most commonly 
      identified type of PIP. Adults with prescribing omissions are more likely to be 
      >/=40 years old or to be prescribed with <5 medications. Adults with dosing 
      problems were more likely >/=50 years old, or have had a fasting blood sugar (FBS) 
      level out of the target range (80-130 mg/dL). Conclusions: IMPACT2DM is a 
      clinically valid PIP identification tool for application in an Ethiopian 
      outpatient setting. Health professionals should be alert to check for potential 
      prescribing omissions for adults >/=40 years old and dosing problems for adults 
      with an FBS level out of the target range or >50 years.
FAU - Ayalew, Mohammed B
AU  - Ayalew MB
AD  - Pharmacy, School of Rural Medicine, University of New England, Armidale, NSW, 
      Australia. RINGGOLD: 1319
AD  - Department of Clinical Pharmacy, School of Pharmacy, University of Gondar, 
      Gondar, Ethiopia.
FAU - Dieberg, Gudrun
AU  - Dieberg G
AD  - Biomedical Science, School of Science and Technology, University of New England, 
      Armidale, NSW, Australia. RINGGOLD: 1319
FAU - Quirk, Frances
AU  - Quirk F
AD  - School of Rural Medicine, University of New England, Armidale, NSW, Australia. 
      RINGGOLD: 1319
FAU - Spark, Marion J
AU  - Spark MJ
AUID- ORCID: 0000-0001-5240-8217
AD  - Pharmacy, School of Rural Medicine, University of New England, Armidale, NSW, 
      Australia. RINGGOLD: 1319
LA  - eng
PT  - Journal Article
DEP - 20221216
PL  - United States
TA  - J Pharm Pract
JT  - Journal of pharmacy practice
JID - 8900945
SB  - IM
OTO - NOTNLM
OT  - Ethiopia
OT  - IMPACT2DM
OT  - potentially inappropriate prescribing
OT  - prescribing omission
OT  - type 2 DM
COIS- Declaration of Conflicting InterestsThe author(s) declared no potential conflicts 
      of interest with respect to the research, authorship, and/or publication of this 
      article.
EDAT- 2022/12/17 06:00
MHDA- 2022/12/17 06:00
CRDT- 2022/12/16 18:42
PHST- 2022/12/17 06:00 [pubmed]
PHST- 2022/12/17 06:00 [medline]
PHST- 2022/12/16 18:42 [entrez]
AID - 10.1177/08971900221145219 [doi]
PST - ppublish
SO  - J Pharm Pract. 2024 Jun;37(3):546-556. doi: 10.1177/08971900221145219. Epub 2022 
      Dec 16.