PMID- 36537385 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230427 IS - 2303-9027 (Print) IS - 2226-7190 (Electronic) IS - 2226-7190 (Linking) VI - 11 IP - 6 DP - 2022 Nov-Dec TI - Feasibility and efficacy of endoscopic reintervention after covered metal stent placement for EUS-guided hepaticogastrostomy: A multicenter experience. PG - 478-486 LID - 10.4103/EUS-D-22-00029 [doi] AB - BACKGROUND AND OBJECTIVES: Although the use of a long metal stent is favored for EUS-guided hepaticogastrostomy (EUS-HGS) for the relief of malignant biliary obstruction (MBO), endoscopic reintervention (E-RI) at the time of recurrent biliary obstruction (RBO) is challenging due to a long intragastric portion. This study evaluated the feasibility and safety of E-RI after a long partially covered metal stent (L-PCMS) placement during EUS-HGS. MATERIALS AND METHODS: We performed a multicenter retrospective study between January 2015 and December 2019 examining patients with MBO who underwent E-RI for RBO through the EUS-HGS route after the L-PCMS placement. Technical and clinical success rates, details of E-RI, adverse events (AEs), stent patency, and survival time were evaluated. RESULTS: Thirty-three patients at eight referral centers in Japan who underwent E-RI through the EUS-HGS route were enrolled. The location of MBO was distal in 54.5%. The median intragastric length of the L-PCMS was 5 cm. As the first E-RI attempt, E-RI via the distal end of the existing L-PCMS was successful in 60.6%. The overall technical and clinical success rates of E-RI were 100% and 81.8%, respectively. Liver abscess was noted in one patient. A proximal biliary stricture was associated with the clinical ineffectiveness of E-RI in multivariable analysis (odds ratio, 12.5, P = 0.04). The median survival and stent patency duration after E-RI were 140 and 394 days, respectively. CONCLUSIONS: Our study findings suggest that E-RI for RBO after EUS-HGS with a L-PCMS is technically feasible and clinically effective, without any severe AEs, especially for patients with distal MBO. FAU - Minaga, Kosuke AU - Minaga K AD - Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka-Sayama, Japan. FAU - Kitano, Masayuki AU - Kitano M AD - Second Department of Internal Medicine, Wakayama Medical University, Wakayama, Japan. FAU - Uenoyama, Yoshito AU - Uenoyama Y AD - Department of Gastroenterology, Japan Red Cross Wakayama Medical Center, Wakayama, Japan. FAU - Hatamaru, Keiichi AU - Hatamaru K AD - Second Department of Internal Medicine, Wakayama Medical University, Wakayama, Japan. FAU - Shiomi, Hideyuki AU - Shiomi H AD - Department of Internal Medicine, Division of Gastroenterology, Kobe University Graduate School of Medicine, Kobe, Japan. FAU - Ikezawa, Kenji AU - Ikezawa K AD - Department of Hepatobiliary and Pancreatic Oncology, Osaka International Cancer Institute, Osaka, Japan. FAU - Miyagahara, Tsukasa AU - Miyagahara T AD - Department of Gastroenterology, Nakatsu Municipal Hospital, Nakatsu, Japan. FAU - Imai, Hajime AU - Imai H AD - Department of Gastroenterology, Okanami General Hospital, Iga, Japan. FAU - Fujimori, Nao AU - Fujimori N AD - Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan. FAU - Matsumoto, Hisakazu AU - Matsumoto H AD - Department of Gastroenterology, Japan Red Cross Wakayama Medical Center, Wakayama, Japan. FAU - Shimokawa, Yuzo AU - Shimokawa Y AD - Department of Gastroenterology, Nakatsu Municipal Hospital, Nakatsu, Japan. FAU - Masuda, Atsuhiro AU - Masuda A AD - Department of Internal Medicine, Division of Gastroenterology, Kobe University Graduate School of Medicine, Kobe, Japan. FAU - Takenaka, Mamoru AU - Takenaka M AD - Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka-Sayama, Japan. FAU - Kudo, Masatoshi AU - Kudo M AD - Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka-Sayama, Japan. FAU - Chiba, Yasutaka AU - Chiba Y AD - Clinical Research Center, Kindai University Hospital, Osaka-Sayama, Japan. LA - eng PT - Journal Article PL - China TA - Endosc Ultrasound JT - Endoscopic ultrasound JID - 101622292 PMC - PMC9921972 OTO - NOTNLM OT - EUS OT - EUS-guided biliary drainage OT - hepaticogastrostomy OT - malignant biliary obstruction OT - reintervention COIS- None EDAT- 2022/12/21 06:00 MHDA- 2022/12/21 06:01 PMCR- 2022/12/05 CRDT- 2022/12/20 06:14 PHST- 2022/12/20 06:14 [entrez] PHST- 2022/12/21 06:00 [pubmed] PHST- 2022/12/21 06:01 [medline] PHST- 2022/12/05 00:00 [pmc-release] AID - EndoscUltrasound_2022_11_6_478_362657 [pii] AID - EUS-11-478 [pii] AID - 10.4103/EUS-D-22-00029 [doi] PST - ppublish SO - Endosc Ultrasound. 2022 Nov-Dec;11(6):478-486. doi: 10.4103/EUS-D-22-00029.