PMID- 36543706
OWN - NLM
STAT- MEDLINE
DCOM- 20230214
LR  - 20230219
IS  - 1590-3729 (Electronic)
IS  - 0939-4753 (Linking)
VI  - 33
IP  - 2
DP  - 2023 Feb
TI  - Effects of whey protein supplementation on adiposity, body weight, and glycemic 
      parameters: A synthesis of evidence.
PG  - 258-274
LID - S0939-4753(22)00397-0 [pii]
LID - 10.1016/j.numecd.2022.09.014 [doi]
AB  - AIMS: The aim of this review was to analyze the evidence of whey protein 
      supplementation on body weight, fat mass, lean mass and glycemic parameters in 
      subjects with overweight or type 2 diabetes mellitus (T2DM) undergoing calorie 
      restriction or with ad libitum intake. DATA SYNTHESIS: Overweight and obesity are 
      considered risk factors for the development of chronic noncommunicable diseases 
      such as T2DM. Calorie restriction is a dietary therapy that reduces weight and 
      fat mass, promotes the improvement of glycemic parameters, and decreases muscle 
      mass. The maintenance of muscle mass during weight loss is necessary in view of 
      its implication in preventing chronic diseases and improving functional capacity 
      and quality of life. The effects of increased protein consumption on attenuating 
      muscle loss and reducing body fat during calorie restriction or ad libitum intake 
      in overweight individuals are discussed. Some studies have demonstrated the 
      positive effects of whey protein supplementation on improving satiety and 
      postprandial glycemic control in short term; however, it remains unclear whether 
      long-term whey protein supplementation can positively affect glycemic parameters. 
      CONCLUSIONS: Although whey protein is considered to have a high nutritional 
      quality, its effects in the treatment of overweight, obese individuals and those 
      with T2DM undergoing calorie restriction or ad libitum intake are still 
      inconclusive.
CI  - Copyright (c) 2022 The Italian Diabetes Society, the Italian Society for the Study 
      of Atherosclerosis, the Italian Society of Human Nutrition and the Department of 
      Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. 
      All rights reserved.
FAU - Giglio, Bruna M
AU  - Giglio BM
AD  - Faculty of Nutrition, Federal University of Goias, Goiania, GO, Brazil.
FAU - Lobo, Patricia C B
AU  - Lobo PCB
AD  - Faculty of Nutrition, Federal University of Goias, Goiania, GO, Brazil.
FAU - Pimentel, Gustavo D
AU  - Pimentel GD
AD  - Faculty of Nutrition, Federal University of Goias, Goiania, GO, Brazil. 
      Electronic address: gupimentel@yahoo.com.br.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20220928
PL  - Netherlands
TA  - Nutr Metab Cardiovasc Dis
JT  - Nutrition, metabolism, and cardiovascular diseases : NMCD
JID - 9111474
RN  - 0 (Whey Proteins)
SB  - IM
MH  - Humans
MH  - Whey Proteins/adverse effects
MH  - *Overweight/diagnosis
MH  - Adiposity
MH  - *Diabetes Mellitus, Type 2/diagnosis/prevention & control
MH  - Quality of Life
MH  - Body Mass Index
MH  - Obesity
MH  - Dietary Supplements/adverse effects
MH  - Body Weight
OTO - NOTNLM
OT  - Body weight maintenance
OT  - Calorie restriction
OT  - Obesity
OT  - Whey protein
EDAT- 2022/12/22 06:00
MHDA- 2023/02/15 06:00
CRDT- 2022/12/21 21:57
PHST- 2022/02/11 00:00 [received]
PHST- 2022/09/16 00:00 [revised]
PHST- 2022/09/19 00:00 [accepted]
PHST- 2022/12/22 06:00 [pubmed]
PHST- 2023/02/15 06:00 [medline]
PHST- 2022/12/21 21:57 [entrez]
AID - S0939-4753(22)00397-0 [pii]
AID - 10.1016/j.numecd.2022.09.014 [doi]
PST - ppublish
SO  - Nutr Metab Cardiovasc Dis. 2023 Feb;33(2):258-274. doi: 
      10.1016/j.numecd.2022.09.014. Epub 2022 Sep 28.