PMID- 36550604
OWN - NLM
STAT- MEDLINE
DCOM- 20221226
LR  - 20221226
IS  - 1473-6500 (Electronic)
IS  - 0952-7907 (Linking)
VI  - 36
IP  - 1
DP  - 2023 Feb 1
TI  - Is venoarterial extracorporeal membrane oxygenation an option for managing septic 
      shock.
PG  - 45-49
LID - 10.1097/ACO.0000000000001206 [doi]
AB  - PURPOSE OF REVIEW: To describe sepsis-induced cardiomyopathy. Discuss indications 
      and current evidence of using venoarterial extracorporeal membrane oxygenation 
      (VA-ECMO) in setting of sepsis-induced cardiomyopathy. RECENT FINDINGS: Recent 
      data suggests a survival benefit with the use of VA-ECMO in patients with septic 
      shock complicated by septic-induced cardiomyopathy with severe left ventricular 
      systolic dysfunction. VA-ECMO was associated with poor outcomes in adults with 
      septic shock without severe systolic dysfunction. The evidence is generated from 
      retrospective and meta-analysis of observational studies. SUMMARY: Sepsis-induced 
      cardiomyopathy is an increasingly recognized entity characterized by reversible 
      ventricular dysfunction in the setting of sepsis. When hypotension persists 
      despite standard management of septic shock (e.g. adequate fluid resuscitation, 
      vasopressors, inotropes) and there is evidence of severe cardiac systolic 
      dysfunction and end-organ hypoperfusion, VA-ECMO should be considered as a bridge 
      therapy to recovery. VA-ECMO should not be used for isolated vasodilatory septic 
      shock without significant myocardial dysfunction.
CI  - Copyright (c) 2022 Wolters Kluwer Health, Inc. All rights reserved.
FAU - Helwani, Mohammad A
AU  - Helwani MA
AD  - Washington University, Department of Anesthesiology, St. Louis, Missouri.
FAU - Lim, Aaron
AU  - Lim A
AD  - Virginia Commonwealth University, Richmond, Virginia, USA.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
DEP - 20221115
PL  - United States
TA  - Curr Opin Anaesthesiol
JT  - Current opinion in anaesthesiology
JID - 8813436
SB  - IM
MH  - Adult
MH  - Humans
MH  - *Shock, Septic/complications/therapy
MH  - Retrospective Studies
MH  - *Extracorporeal Membrane Oxygenation
MH  - *Hypotension
EDAT- 2022/12/23 06:00
MHDA- 2022/12/27 06:00
CRDT- 2022/12/22 23:59
PHST- 2022/12/22 23:59 [entrez]
PHST- 2022/12/23 06:00 [pubmed]
PHST- 2022/12/27 06:00 [medline]
AID - 00001503-202302000-00010 [pii]
AID - 10.1097/ACO.0000000000001206 [doi]
PST - ppublish
SO  - Curr Opin Anaesthesiol. 2023 Feb 1;36(1):45-49. doi: 
      10.1097/ACO.0000000000001206. Epub 2022 Nov 15.