PMID- 36551399 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20221225 IS - 2079-6382 (Print) IS - 2079-6382 (Electronic) IS - 2079-6382 (Linking) VI - 11 IP - 12 DP - 2022 Dec 2 TI - An Initial Report of the Antimicrobial Activities of Volatiles Produced during Rapid Volatilization of Oils. LID - 10.3390/antibiotics11121742 [doi] LID - 1742 AB - Aerosols generated through volatilization and subsequent recondensation of oil vapors have been used as obscurant (smoke) screens during military operations since the early twentieth century. Specifically, a petroleum middle distillate known as the fog oil (FO) has been used in US military battlefields to create obscurant smoke screens. During a study on the feasibility of replacing petroleum-derived FO with vegetable oil-derived esters such as methyl soyate (MS), it was observed that that FO and MS aerosols and vapors did not exhibit detectable mutagenic activity but were lethal to Ames strains bacteria even after very short exposure periods. These results opened the potential use of oil-derived vapors as antimicrobial agents. Subsequent studies showed that optimal aerosol/vapor production conditions could further enhance disinfectant efficiency. For this purpose, we examined the antimicrobial activities of mineral oils and biogenic oil ester aerosols/vapors against a wide range of Gram-positive and Gram-negative bacteria. The results of the study showed that the aerosols/vapors obtained from mineral oil or vegetable oil ester under proper conditions can serve as an excellent antibacterial disinfectant. FAU - Ramamurthy, Sangeetha AU - Ramamurthy S AD - Department of Microbiology, Missouri University of Science and Technology, Rolla, MO 65401, USA. FAU - Kopel, Jonathan AU - Kopel J AD - School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA. FAU - Westenberg, David AU - Westenberg D AUID- ORCID: 0000-0003-3510-0311 AD - Department of Microbiology, Missouri University of Science and Technology, Rolla, MO 65401, USA. FAU - Kapila, Shubhender AU - Kapila S AD - Department of Chemistry, Missouri University of Science and Technology, Rolla, MO 65401, USA. LA - eng PT - Journal Article DEP - 20221202 PL - Switzerland TA - Antibiotics (Basel) JT - Antibiotics (Basel, Switzerland) JID - 101637404 PMC - PMC9774546 OTO - NOTNLM OT - antimicrobials OT - bacteria OT - disinfectants OT - fog oil OT - methyl soyate OT - vapors OT - viruses COIS- The authors declare no conflict of interest. EDAT- 2022/12/24 06:00 MHDA- 2022/12/24 06:01 PMCR- 2022/12/02 CRDT- 2022/12/23 01:09 PHST- 2022/10/15 00:00 [received] PHST- 2022/10/29 00:00 [revised] PHST- 2022/12/01 00:00 [accepted] PHST- 2022/12/23 01:09 [entrez] PHST- 2022/12/24 06:00 [pubmed] PHST- 2022/12/24 06:01 [medline] PHST- 2022/12/02 00:00 [pmc-release] AID - antibiotics11121742 [pii] AID - antibiotics-11-01742 [pii] AID - 10.3390/antibiotics11121742 [doi] PST - epublish SO - Antibiotics (Basel). 2022 Dec 2;11(12):1742. doi: 10.3390/antibiotics11121742.