PMID- 36553263
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20221225
IS  - 2227-9067 (Print)
IS  - 2227-9067 (Electronic)
IS  - 2227-9067 (Linking)
VI  - 9
IP  - 12
DP  - 2022 Nov 25
TI  - Acute Appendicitis as the Initial Presentation of Kawasaki Disease Shock Syndrome 
      in Children.
LID - 10.3390/children9121819 [doi]
LID - 1819
AB  - Kawasaki disease shock syndrome (KDSS) is a severe form of Kawasaki disease (KD). 
      The hemodynamic instability and atypical manifestations of this syndrome delay 
      its correct diagnosis and timely treatment. We report here an eight-year-old girl 
      who presented with appendicitis. Her fever persisted after appendectomy, 
      accompanied by hemodynamic instability. The girl was diagnosed with KDSS. 
      Intravenous immunoglobulin (IVIG) and corticosteroids were administered. Her 
      symptoms resolved. She had left coronary artery dilatation, which resolved three 
      months later. We also reviewed two other possible cases identified as KDSS with 
      appendicitis. These cases have a more atypical clinical course, prolonged 
      treatment, and a higher rate of IVIG resistance. Better awareness of KDSS is 
      needed for early diagnosis and treatment in children experiencing prolonged fever 
      after appendectomy.
FAU - Chang, Yuan-Hao
AU  - Chang YH
AUID- ORCID: 0000-0003-1619-9467
AD  - Department of Pediatrics, Hsinchu MacKay Memorial Hospital, Hsinchu City 30071, 
      Taiwan.
FAU - Lin, Chien-Yu
AU  - Lin CY
AUID- ORCID: 0000-0003-4630-8724
AD  - Department of Pediatrics, Hsinchu MacKay Memorial Hospital, Hsinchu City 30071, 
      Taiwan.
FAU - Liu, Lu-Hang
AU  - Liu LH
AD  - Department of Pediatrics, Hsinchu MacKay Memorial Hospital, Hsinchu City 30071, 
      Taiwan.
FAU - Huang, Fu-Huan
AU  - Huang FH
AUID- ORCID: 0000-0002-2747-2900
AD  - Division of Pediatric Surgery, Department of Surgery, Taipei Medical University 
      Hospital, Taipei City 110, Taiwan.
FAU - Cheng, Yu-Jyun
AU  - Cheng YJ
AD  - Department of Pediatrics, Changhua Christian Children's Hospital, Changhua City 
      50050, Taiwan.
LA  - eng
PT  - Case Reports
DEP - 20221125
PL  - Switzerland
TA  - Children (Basel)
JT  - Children (Basel, Switzerland)
JID - 101648936
PMC - PMC9776465
OTO - NOTNLM
OT  - Kawasaki disease
OT  - Kawasaki disease shock syndrome
OT  - appendicitis
OT  - coronary artery dilatation
OT  - intravenous immunoglobulin
COIS- The authors declare no conflict of interest.
EDAT- 2022/12/24 06:00
MHDA- 2022/12/24 06:01
PMCR- 2022/11/25
CRDT- 2022/12/23 01:20
PHST- 2022/10/27 00:00 [received]
PHST- 2022/11/17 00:00 [revised]
PHST- 2022/11/22 00:00 [accepted]
PHST- 2022/12/23 01:20 [entrez]
PHST- 2022/12/24 06:00 [pubmed]
PHST- 2022/12/24 06:01 [medline]
PHST- 2022/11/25 00:00 [pmc-release]
AID - children9121819 [pii]
AID - children-09-01819 [pii]
AID - 10.3390/children9121819 [doi]
PST - epublish
SO  - Children (Basel). 2022 Nov 25;9(12):1819. doi: 10.3390/children9121819.