PMID- 36553640
OWN - NLM
STAT- MEDLINE
DCOM- 20221226
LR  - 20230109
IS  - 2073-4425 (Electronic)
IS  - 2073-4425 (Linking)
VI  - 13
IP  - 12
DP  - 2022 Dec 16
TI  - Human Genetic Research in Wallacea and Sahul: Recent Findings and Future 
      Prospects.
LID - 10.3390/genes13122373 [doi]
LID - 2373
AB  - Genomic sequence data from worldwide human populations have provided a range of 
      novel insights into our shared ancestry and the historical migrations that have 
      shaped our global genetic diversity. However, a comprehensive understanding of 
      these fundamental questions has been impeded by the lack of inclusion of many 
      Indigenous populations in genomic surveys, including those from the Wallacean 
      archipelago (which comprises islands of present-day Indonesia located east and 
      west of Wallace's and Lydekker's Lines, respectively) and the former continent of 
      Sahul (which once combined New Guinea and Australia during lower sea levels in 
      the Pleistocene). Notably, these regions have been important areas of human 
      evolution throughout the Late Pleistocene, as documented by diverse fossil and 
      archaeological records which attest to the regional presence of multiple hominin 
      species prior to the arrival of anatomically modern human (AMH) migrants. In this 
      review, we collate and discuss key findings from the past decade of population 
      genetic and phylogeographic literature focussed on the hominin history in 
      Wallacea and Sahul. Specifically, we examine the evidence for the timing and 
      direction of the ancient AMH migratory movements and subsequent hominin mixing 
      events, emphasising several novel but consistent results that have important 
      implications for addressing these questions. Finally, we suggest potentially 
      lucrative directions for future genetic research in this key region of human 
      evolution.
FAU - Taufik, Leonard
AU  - Taufik L
AD  - Australian Centre for Ancient DNA, School of Biological Sciences, University of 
      Adelaide, Adelaide, SA 5005, Australia.
AD  - Centre of Excellence for Australian Biodiversity and Heritage, University of 
      Adelaide, Adelaide, SA 5005, Australia.
AD  - Mochtar Riady Institute for Nanotechnology, Tangerang 15810, Indonesia.
FAU - Teixeira, Joao C
AU  - Teixeira JC
AUID- ORCID: 0000-0001-6417-4702
AD  - Australian Centre for Ancient DNA, School of Biological Sciences, University of 
      Adelaide, Adelaide, SA 5005, Australia.
AD  - Centre of Excellence for Australian Biodiversity and Heritage, University of 
      Adelaide, Adelaide, SA 5005, Australia.
AD  - Evolution of Cultural Diversity Initiative, Australian National University, 
      Canberra, ACT 2601, Australia.
AD  - Centre for Interdisciplinary Studies, University of Coimbra, 3004-531 Coimbra, 
      Portugal.
FAU - Llamas, Bastien
AU  - Llamas B
AUID- ORCID: 0000-0002-5550-9176
AD  - Australian Centre for Ancient DNA, School of Biological Sciences, University of 
      Adelaide, Adelaide, SA 5005, Australia.
AD  - Centre of Excellence for Australian Biodiversity and Heritage, University of 
      Adelaide, Adelaide, SA 5005, Australia.
AD  - Environment Institute, University of Adelaide, Adelaide, SA 5005, Australia.
AD  - National Centre for Indigenous Genomics, Australian National University, 
      Canberra, ACT 2601, Australia.
AD  - Indigenous Genomics Research Group, Telethon Kids Institute, Adelaide, SA 5001, 
      Australia.
FAU - Sudoyo, Herawati
AU  - Sudoyo H
AD  - Mochtar Riady Institute for Nanotechnology, Tangerang 15810, Indonesia.
FAU - Tobler, Raymond
AU  - Tobler R
AD  - Australian Centre for Ancient DNA, School of Biological Sciences, University of 
      Adelaide, Adelaide, SA 5005, Australia.
AD  - Centre of Excellence for Australian Biodiversity and Heritage, University of 
      Adelaide, Adelaide, SA 5005, Australia.
AD  - Evolution of Cultural Diversity Initiative, Australian National University, 
      Canberra, ACT 2601, Australia.
FAU - Purnomo, Gludhug A
AU  - Purnomo GA
AUID- ORCID: 0000-0001-7616-5977
AD  - Australian Centre for Ancient DNA, School of Biological Sciences, University of 
      Adelaide, Adelaide, SA 5005, Australia.
AD  - Centre of Excellence for Australian Biodiversity and Heritage, University of 
      Adelaide, Adelaide, SA 5005, Australia.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20221216
PL  - Switzerland
TA  - Genes (Basel)
JT  - Genes
JID - 101551097
SB  - IM
MH  - Animals
MH  - Humans
MH  - *Hominidae/genetics
MH  - Human Migration
MH  - New Guinea
MH  - Australia
MH  - Phylogeography
MH  - *Coleoptera
PMC - PMC9778601
OTO - NOTNLM
OT  - Sahul
OT  - Wallacea
OT  - ancient DNA
OT  - human migrations
OT  - phylogeography
COIS- The authors declare no conflict of interest.
EDAT- 2022/12/24 06:00
MHDA- 2022/12/27 06:00
PMCR- 2022/12/16
CRDT- 2022/12/23 01:22
PHST- 2022/11/11 00:00 [received]
PHST- 2022/12/08 00:00 [revised]
PHST- 2022/12/13 00:00 [accepted]
PHST- 2022/12/23 01:22 [entrez]
PHST- 2022/12/24 06:00 [pubmed]
PHST- 2022/12/27 06:00 [medline]
PHST- 2022/12/16 00:00 [pmc-release]
AID - genes13122373 [pii]
AID - genes-13-02373 [pii]
AID - 10.3390/genes13122373 [doi]
PST - epublish
SO  - Genes (Basel). 2022 Dec 16;13(12):2373. doi: 10.3390/genes13122373.