PMID- 36560579
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20221227
IS  - 2076-393X (Print)
IS  - 2076-393X (Electronic)
IS  - 2076-393X (Linking)
VI  - 10
IP  - 12
DP  - 2022 Dec 16
TI  - SARS-CoV-2 Seroprevalence in Unvaccinated Adults in Thailand in November 2021.
LID - 10.3390/vaccines10122169 [doi]
LID - 2169
AB  - Between the first case of COVID-19 in January 2020 and the end of 2021, Thailand 
      experienced four waves of the epidemic. The third and fourth waves were caused by 
      the alpha and delta strains from April 2021 to November 2021. Serosurveillance 
      studies provide snapshots of the true scale of the outbreak, including the 
      asymptomatic infections that could not be fully captured by a hospital-based case 
      detection system. We aimed to investigate the distribution of SARs-CoV-2 
      seroprevalence in unvaccinated adults after the delta wave outbreak. From 
      November to December 2021, we conducted a cross-sectional survey study in 12 
      public health areas (PHAs) across Thailand. A total of 26,717 blood samples were 
      collected and tested for SARs-CoV-2 antibodies (anti-S IgG) using a qualitative 
      immunoassay. The results showed that seropositive prevalence in this cohort was 
      1.4% (95% CI: 1.24 to 1.52). The lowest prevalence was in the northern region 
      (PHA 1) and in central Thailand (PHA 3) at 0.4% (95% CI: 0.15 to 0.95), while the 
      highest was in the southern region of Thailand (PHA 12) at 5.8% (95% CI: 4.48 to 
      7.29). This seropositive prevalence was strikingly lower than the reports from 
      other countries. Our serosurveillance results suggest that the vaccination of 
      unvaccinated groups should be accelerated, especially in the public health areas 
      with the lowest seroprevalence.
FAU - Mahasirimongkol, Surakameth
AU  - Mahasirimongkol S
AD  - Medical Life Sciences Institute, Department of Medical Sciences, Ministry of 
      Public Health, Nonthaburi 11000, Thailand.
FAU - Uppapong, Ballang
AU  - Uppapong B
AD  - Administrative Offices, Department of Medical Sciences, Ministry of Public 
      Health, Nonthaburi 11000, Thailand.
FAU - Puangtubtim, Wiroj
AU  - Puangtubtim W
AD  - Medical Life Sciences Institute, Department of Medical Sciences, Ministry of 
      Public Health, Nonthaburi 11000, Thailand.
FAU - Dhepakson, Panadda
AU  - Dhepakson P
AD  - Medical Life Sciences Institute, Department of Medical Sciences, Ministry of 
      Public Health, Nonthaburi 11000, Thailand.
FAU - Panyajai, Parnuphan
AU  - Panyajai P
AD  - Medical Life Sciences Institute, Department of Medical Sciences, Ministry of 
      Public Health, Nonthaburi 11000, Thailand.
FAU - Thawong, Naphatcha
AU  - Thawong N
AD  - Medical Life Sciences Institute, Department of Medical Sciences, Ministry of 
      Public Health, Nonthaburi 11000, Thailand.
FAU - Pinyosukhee, Nadthanan
AU  - Pinyosukhee N
AD  - Medical Life Sciences Institute, Department of Medical Sciences, Ministry of 
      Public Health, Nonthaburi 11000, Thailand.
FAU - Rojanawiwat, Archawin
AU  - Rojanawiwat A
AD  - National Institute of Health, Department of Medical Sciences, Ministry of Public 
      Health, Nonthaburi 11000, Thailand.
FAU - Wichukchinda, Nuanjun
AU  - Wichukchinda N
AD  - Medical Sciences Technical Office, Department of Medical Sciences, Ministry of 
      Public Health, Nonthaburi 11000, Thailand.
FAU - Soonthorncharttrawat, Sakulrat
AU  - Soonthorncharttrawat S
AD  - Medical Life Sciences Institute, Department of Medical Sciences, Ministry of 
      Public Health, Nonthaburi 11000, Thailand.
FAU - Larpardisorn, Kanisorn
AU  - Larpardisorn K
AD  - Medical Life Sciences Institute, Department of Medical Sciences, Ministry of 
      Public Health, Nonthaburi 11000, Thailand.
FAU - Amonyingcharoen, Sumet
AU  - Amonyingcharoen S
AD  - Medical Life Sciences Institute, Department of Medical Sciences, Ministry of 
      Public Health, Nonthaburi 11000, Thailand.
FAU - Juntaped, Kritchai
AU  - Juntaped K
AD  - Medical Life Sciences Institute, Department of Medical Sciences, Ministry of 
      Public Health, Nonthaburi 11000, Thailand.
FAU - Chaiyakum, Tassanee
AU  - Chaiyakum T
AD  - Medical Life Sciences Institute, Department of Medical Sciences, Ministry of 
      Public Health, Nonthaburi 11000, Thailand.
FAU - Tongkamsen, Chayada
AU  - Tongkamsen C
AD  - Medical Life Sciences Institute, Department of Medical Sciences, Ministry of 
      Public Health, Nonthaburi 11000, Thailand.
FAU - Srilaket, Jeerapa
AU  - Srilaket J
AD  - Medical Life Sciences Institute, Department of Medical Sciences, Ministry of 
      Public Health, Nonthaburi 11000, Thailand.
FAU - Chipatoom, Jiratikamon
AU  - Chipatoom J
AD  - Medical Life Sciences Institute, Department of Medical Sciences, Ministry of 
      Public Health, Nonthaburi 11000, Thailand.
FAU - Wichajarn, Rattanawadee
AU  - Wichajarn R
AD  - Medical Life Sciences Institute, Department of Medical Sciences, Ministry of 
      Public Health, Nonthaburi 11000, Thailand.
FAU - Chatchawankanpanich, Nutchanat
AU  - Chatchawankanpanich N
AD  - Medical Life Sciences Institute, Department of Medical Sciences, Ministry of 
      Public Health, Nonthaburi 11000, Thailand.
FAU - Pattarapreeyakul, Lapasrada
AU  - Pattarapreeyakul L
AD  - Medical Life Sciences Institute, Department of Medical Sciences, Ministry of 
      Public Health, Nonthaburi 11000, Thailand.
FAU - Chaiya, Porntip
AU  - Chaiya P
AD  - Medical Life Sciences Institute, Department of Medical Sciences, Ministry of 
      Public Health, Nonthaburi 11000, Thailand.
FAU - Mongkolsiri, Kaveewan
AU  - Mongkolsiri K
AD  - Medical Life Sciences Institute, Department of Medical Sciences, Ministry of 
      Public Health, Nonthaburi 11000, Thailand.
FAU - Tuntigumthon, Suthida
AU  - Tuntigumthon S
AD  - Medical Life Sciences Institute, Department of Medical Sciences, Ministry of 
      Public Health, Nonthaburi 11000, Thailand.
FAU - Sophondilok, Kritsamon
AU  - Sophondilok K
AD  - Medical Life Sciences Institute, Department of Medical Sciences, Ministry of 
      Public Health, Nonthaburi 11000, Thailand.
FAU - Saengtong, Nalinee
AU  - Saengtong N
AD  - Medical Life Sciences Institute, Department of Medical Sciences, Ministry of 
      Public Health, Nonthaburi 11000, Thailand.
FAU - Jongpitisub, Kodcharad
AU  - Jongpitisub K
AD  - Medical Life Sciences Institute, Department of Medical Sciences, Ministry of 
      Public Health, Nonthaburi 11000, Thailand.
FAU - Sirilak, Supakit
AU  - Sirilak S
AD  - Administrative Offices, Department of Medical Sciences, Ministry of Public 
      Health, Nonthaburi 11000, Thailand.
LA  - eng
GR  - 1500000001/Department of Medical Sciences/
PT  - Journal Article
DEP - 20221216
PL  - Switzerland
TA  - Vaccines (Basel)
JT  - Vaccines
JID - 101629355
PMC - PMC9785861
OTO - NOTNLM
OT  - 2021
OT  - COVID-19
OT  - SARS-CoV-2
OT  - Thailand
OT  - anti-S
OT  - antibody
OT  - seroprevalence
OT  - unvaccinated
COIS- The authors declare no conflict of interest.
EDAT- 2022/12/24 06:00
MHDA- 2022/12/24 06:01
PMCR- 2022/12/16
CRDT- 2022/12/23 02:05
PHST- 2022/09/30 00:00 [received]
PHST- 2022/11/17 00:00 [revised]
PHST- 2022/11/24 00:00 [accepted]
PHST- 2022/12/23 02:05 [entrez]
PHST- 2022/12/24 06:00 [pubmed]
PHST- 2022/12/24 06:01 [medline]
PHST- 2022/12/16 00:00 [pmc-release]
AID - vaccines10122169 [pii]
AID - vaccines-10-02169 [pii]
AID - 10.3390/vaccines10122169 [doi]
PST - epublish
SO  - Vaccines (Basel). 2022 Dec 16;10(12):2169. doi: 10.3390/vaccines10122169.