PMID- 36566397
OWN - NLM
STAT- MEDLINE
DCOM- 20221227
LR  - 20221230
IS  - 1819-2718 (Electronic)
IS  - 1025-9589 (Linking)
VI  - 34
IP  - 4
DP  - 2022 Oct-Dec
TI  - Timi Risk Index, A Simple Tool In Emergency Percutaneous Revascularization For 
      The Prediction Of Contrast Induced Nephropathy.
PG  - 771-777
LID - 10.55519/JAMC-04-10733 [doi]
AB  - BACKGROUND: Contrast induced nephropathy (CIN) is a common complication seen 
      after primary percutaneous coronary intervention (PCI) which can contribute to 
      increased morbidity and mortality in patients of acute ST elevation myocardial 
      infarction (STEMI). Aim of this study was to validate the TIMI Risk Index (TRI) 
      for the risk stratification of CIN in patients undergone primary PCI. METHODS: 
      Consecutive patients of STEMI undergone primary PCI at a tertiary care cardiac 
      center were included for this study. Patients in Killip class IV at presentation, 
      patients with history of any PCI and chronic kidney diseases were excluded from 
      this study. TRI was calculated using the formula " " and post-procedure serum 
      creatinine level increase of either 25% or 0.5 mg/dL was taken as CIN. RESULTS: A 
      total of 507 patients were included in this study out of which 82.2% were males 
      and 17.8% were females. In total 8.7% (44) patients developed CIN. In the 
      receiver operating characteristic (ROC) curve analysis, area under the curve 
      (AUC) for TRI was found to be 0.717, [0.649-0.758] for the prediction of CIN. 
      Sensitive, specificity, positive predictive value and negative predictive value 
      of TRI >22.8 to predict the development of CIN were 59.09%, 76.69%, 19.55% and 
      95.19% respectively. CONCLUSIONS: TIMI risk index is and easy to calculate and 
      readily accessible score which has good predictive value to evaluate the risk of 
      CIN in primary PCI setting.
FAU - Kumar, Rajesh
AU  - Kumar R
AD  - National Institute of Cardiovascular Diseases, Karachi, Pakistan.
FAU - Memon, Aziz-Ur-Rehman
AU  - Memon AU
AD  - National Institute of Cardiovascular Diseases, Karachi, Pakistan.
FAU - Shaikh, Abdul Hakeem
AU  - Shaikh AH
AD  - National Institute of Cardiovascular Diseases, Karachi, Pakistan.
FAU - Huma, Zille
AU  - Huma Z
AD  - National Institute of Cardiovascular Diseases, Karachi, Pakistan.
FAU - Kumar, Vinesh
AU  - Kumar V
AD  - National Institute of Cardiovascular Diseases, Karachi, Pakistan.
FAU - Hussain, Afzal
AU  - Hussain A
AD  - National Institute of Cardiovascular Diseases, Karachi, Pakistan.
FAU - Sial, Jawaid Akbar
AU  - Sial JA
AD  - National Institute of Cardiovascular Diseases, Karachi, Pakistan.
FAU - Saghir, Tahir
AU  - Saghir T
AD  - National Institute of Cardiovascular Diseases, Karachi, Pakistan.
FAU - Achakzai, Abdul Samad
AU  - Achakzai AS
AD  - National Institute of Cardiovascular Diseases, Karachi, Pakistan.
FAU - Karim, Musa
AU  - Karim M
AD  - National Institute of Cardiovascular Diseases, Karachi, Pakistan.
LA  - eng
PT  - Journal Article
PL  - Pakistan
TA  - J Ayub Med Coll Abbottabad
JT  - Journal of Ayub Medical College, Abbottabad : JAMC
JID - 8910750
RN  - 0 (Contrast Media)
SB  - IM
MH  - Male
MH  - Female
MH  - Humans
MH  - *ST Elevation Myocardial Infarction/surgery
MH  - Contrast Media/adverse effects
MH  - Risk Factors
MH  - *Percutaneous Coronary Intervention/adverse effects
MH  - Risk Assessment
MH  - *Kidney Diseases/chemically induced
OTO - NOTNLM
OT  - Contrast induced nephropathy
OT  - TIMI Risk Index; Primary percutaneous coronary intervention
EDAT- 2022/12/26 06:00
MHDA- 2022/12/28 06:00
CRDT- 2022/12/25 14:03
PHST- 2022/12/25 14:03 [entrez]
PHST- 2022/12/26 06:00 [pubmed]
PHST- 2022/12/28 06:00 [medline]
AID - 10733/3396 [pii]
AID - 10.55519/JAMC-04-10733 [doi]
PST - ppublish
SO  - J Ayub Med Coll Abbottabad. 2022 Oct-Dec;34(4):771-777. doi: 
      10.55519/JAMC-04-10733.