PMID- 36570914
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20221227
IS  - 1664-462X (Print)
IS  - 1664-462X (Electronic)
IS  - 1664-462X (Linking)
VI  - 13
DP  - 2022
TI  - Transcriptional profiling of defense responses to Botrytis cinerea infection in 
      leaves of Fragaria vesca plants soil-drenched with beta-aminobutyric acid.
PG  - 1025422
LID - 10.3389/fpls.2022.1025422 [doi]
LID - 1025422
AB  - Grey mold caused by the necrotrophic fungal pathogen Botrytis cinerea can affect 
      leaves, flowers, and berries of strawberry, causing severe pre- and postharvest 
      damage. The defense elicitor beta-aminobutyric acid (BABA) is reported to induce 
      resistance against B. cinerea and many other pathogens in several crop plants. 
      Surprisingly, BABA soil drench of woodland strawberry (Fragaria vesca) plants two 
      days before B. cinerea inoculation caused increased infection in leaf tissues, 
      suggesting that BABA induce systemic susceptibility in F. vesca. To understand 
      the molecular mechanisms involved in B. cinerea susceptibility in leaves of F. 
      vesca plants soil drenched with BABA, we used RNA sequencing to characterize the 
      transcriptional reprogramming 24 h post-inoculation. The number of differentially 
      expressed genes (DEGs) in infected vs. uninfected leaf tissue in BABA-treated 
      plants was 5205 (2237 upregulated and 2968 downregulated). Upregulated genes were 
      involved in pathogen recognition, defense response signaling, and biosynthesis of 
      secondary metabolites (terpenoid and phenylpropanoid pathways), while 
      downregulated genes were involved in photosynthesis and response to auxin. In 
      control plants not treated with BABA, we found a total of 5300 DEGs (2461 
      upregulated and 2839 downregulated) after infection. Most of these corresponded 
      to those in infected leaves of BABA-treated plants but a small subset of DEGs, 
      including genes involved in 'response to biologic stimulus', 'photosynthesis' and 
      'chlorophyll biosynthesis and metabolism', differed significantly between 
      treatments and could play a role in the induced susceptibility of BABA-treated 
      plants.
CI  - Copyright (c) 2022 Badmi, Tengs, Brurberg, Elameen, Zhang, Haugland, Fossdal, 
      Hytonen, Krokene and Thorstensen.
FAU - Badmi, Raghuram
AU  - Badmi R
AD  - Division of Biotechnology and Plant Health, Norwegian Institute of Bioeconomy 
      Research, As, Norway.
FAU - Tengs, Torstein
AU  - Tengs T
AD  - Division of Biotechnology and Plant Health, Norwegian Institute of Bioeconomy 
      Research, As, Norway.
FAU - Brurberg, May Bente
AU  - Brurberg MB
AD  - Division of Biotechnology and Plant Health, Norwegian Institute of Bioeconomy 
      Research, As, Norway.
AD  - Department of Plant Sciences, Norwegian University of Life Sciences (NMBU), As, 
      Norway.
FAU - Elameen, Abdelhameed
AU  - Elameen A
AD  - Division of Biotechnology and Plant Health, Norwegian Institute of Bioeconomy 
      Research, As, Norway.
FAU - Zhang, Yupeng
AU  - Zhang Y
AD  - Division of Biotechnology and Plant Health, Norwegian Institute of Bioeconomy 
      Research, As, Norway.
FAU - Haugland, Lisa Karine
AU  - Haugland LK
AD  - Division of Biotechnology and Plant Health, Norwegian Institute of Bioeconomy 
      Research, As, Norway.
FAU - Fossdal, Carl Gunnar
AU  - Fossdal CG
AD  - Division of Biotechnology and Plant Health, Norwegian Institute of Bioeconomy 
      Research, As, Norway.
FAU - Hytonen, Timo
AU  - Hytonen T
AD  - Department of Agricultural Sciences, University of Helsinki, Helsinki, Finland.
AD  - Organismal and Evolutionary Biology Research Programme, Faculty of Biological and 
      Environmental Sciences, University of Helsinki, Helsinki, Finland.
AD  - Department of Genetics, Genomics and Breeding, National Institute of Agricultural 
      Botany- East Malling Research Station, East Malling, United Kingdom.
FAU - Krokene, Paal
AU  - Krokene P
AD  - Division of Biotechnology and Plant Health, Norwegian Institute of Bioeconomy 
      Research, As, Norway.
FAU - Thorstensen, Tage
AU  - Thorstensen T
AD  - Division of Biotechnology and Plant Health, Norwegian Institute of Bioeconomy 
      Research, As, Norway.
LA  - eng
PT  - Journal Article
DEP - 20221208
PL  - Switzerland
TA  - Front Plant Sci
JT  - Frontiers in plant science
JID - 101568200
PMC - PMC9772985
OTO - NOTNLM
OT  - Botrytis cinerea
OT  - crop protection
OT  - disease resistance
OT  - necrotroph
OT  - strawberry
OT  - transcriptomics
OT  - beta-aminobutyric acid
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2022/12/27 06:00
MHDA- 2022/12/27 06:01
PMCR- 2022/01/01
CRDT- 2022/12/26 04:45
PHST- 2022/08/22 00:00 [received]
PHST- 2022/11/21 00:00 [accepted]
PHST- 2022/12/26 04:45 [entrez]
PHST- 2022/12/27 06:00 [pubmed]
PHST- 2022/12/27 06:01 [medline]
PHST- 2022/01/01 00:00 [pmc-release]
AID - 10.3389/fpls.2022.1025422 [doi]
PST - epublish
SO  - Front Plant Sci. 2022 Dec 8;13:1025422. doi: 10.3389/fpls.2022.1025422. 
      eCollection 2022.