PMID- 36575033
OWN - NLM
STAT- MEDLINE
DCOM- 20221229
LR  - 20230103
IS  - 0015-6426 (Print)
IS  - 0015-6426 (Linking)
VI  - 63
IP  - 6
DP  - 2022
TI  - [Determination of Chlorothalonil Metabolite I in Livestock Products by LC-MS/MS].
PG  - 195-201
LID - 10.3358/shokueishi.63.195 [doi]
AB  - An analytical method based on LC-MS/MS was developed for the determination of 
      chlorothalonil metabolite I in livestock products. Chlorothalonil metabolite I in 
      livestock products was extracted with acetone. The crude extracts were defatted 
      by acetonitrile and n-hexane partitioning. Cleanup was carried out using a 
      combination of ethylene diamine-N-propyl silylation silica gel (PSA) and silica 
      gel (SI) mini columns with acidic condition. The sample solution was subjected to 
      LC-MS/MS using an external solvent calibration curve. The average recovery (n=5) 
      of chlorothalonil metabolite I from five types of livestock products (cattle 
      muscle, cattle fat, cattle liver, milk and egg) spike at the maximum residue 
      limits (MRLs) or at a uniform limit of 0.01 mg/kg was 97.1-102.9%, with a 
      relative standard deviation of 1.4-6.8%. The limit of quantitation of the 
      developed method was calculated to be 0.01 mg/kg.
FAU - Kobayashi, Maki
AU  - Kobayashi M
AD  - Tokyo Metropolitan Institute of Public Health.
FAU - Sakai, Naoko
AU  - Sakai N
AD  - Tokyo Metropolitan Institute of Public Health.
FAU - Ohmachi, Yuki
AU  - Ohmachi Y
AD  - Tokyo Metropolitan Institute of Public Health.
FAU - Morita, Yuka
AU  - Morita Y
AD  - Tokyo Metropolitan Institute of Public Health.
FAU - Nemoto, Satoru
AU  - Nemoto S
FAU - Ohtsuka, Kenji
AU  - Ohtsuka K
AD  - Tokyo Metropolitan Institute of Public Health.
LA  - jpn
PT  - English Abstract
PT  - Journal Article
PL  - Japan
TA  - Shokuhin Eiseigaku Zasshi
JT  - Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan
JID - 0142214
RN  - J718M71A7A (tetrachloroisophthalonitrile)
RN  - 60650-90-0 (Silica Gel)
SB  - IM
MH  - Animals
MH  - Cattle
MH  - *Livestock
MH  - *Tandem Mass Spectrometry
MH  - Chromatography, Liquid
MH  - Silica Gel
OTO - NOTNLM
OT  - 2,5,6-Trichloro-4-hydroxyisophthalonitrile
OT  - LC-MS/MS
OT  - chlorothalonil metabolite I
OT  - livestock products
EDAT- 2022/12/28 06:00
MHDA- 2022/12/30 06:00
CRDT- 2022/12/27 20:53
PHST- 2022/12/27 20:53 [entrez]
PHST- 2022/12/28 06:00 [pubmed]
PHST- 2022/12/30 06:00 [medline]
AID - 10.3358/shokueishi.63.195 [doi]
PST - ppublish
SO  - Shokuhin Eiseigaku Zasshi. 2022;63(6):195-201. doi: 10.3358/shokueishi.63.195.