PMID- 36579536
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230308
IS  - 2075-4426 (Print)
IS  - 2075-4426 (Electronic)
IS  - 2075-4426 (Linking)
VI  - 12
IP  - 11
DP  - 2022 Oct 30
TI  - Local Infiltrations in Patients with Radiculopathy or Chronic Low Back Pain Due 
      to Segment Degeneration-Only A Diagnostic Value?
LID - 10.3390/jpm12111791 [doi]
LID - 1791
AB  - The purpose of this study was to investigate the differences in the therapeutic 
      effectiveness of CT-assisted infiltration of a local anesthetic + corticosteroid 
      between nerve root and facet joint capsule in patients with chronic complaints. 
      In this prospective trial with a 12-month follow-up, a total of 250 patients with 
      chronic low back pain and radiculopathy were assigned to two groups. In the first 
      group, patients with specific lumbar pain due to spondyloarthritis received 
      periarticular facet joint capsule infiltration (FJI). In the second group, 
      patients with monoradicular pain received periradicular infiltration (PRI) via an 
      extraforaminal selective nerve block. Clinical improvement after FJI and PRI 
      regarding pain (NRS), function (ODI), satisfaction (McNab), and health related 
      quality of life (SF-36) were compared. Minimally clinically important difference 
      (MCID) served as the threshold for therapeutic effectiveness evaluation. A total 
      of 196 patients were available for final analysis. With respect to the pain 
      reduction and functional improvement (ODI, NRSoverall, and NRSback), the PRI 
      group performed significantly better (ptreatment < 0.001) and longer over time 
      (ptreatment x time 0.001) than the FJI group. Regarding pain and function, only 
      PRI demonstrated a durable improvement larger than MCID. A significant and 
      durable therapeutic value was found only after receiving PRI but not after FJI in 
      patients with chronic pain.
FAU - Lindemann, Chris
AU  - Lindemann C
AD  - Orthopedic Department, Jena University Hospital, Campus Eisenberg, 07607 
      Eisenberg, Germany.
FAU - Zippelius, Timo
AU  - Zippelius T
AD  - Department of Orthopedic Surgery, University of Ulm, 89081 Ulm, Germany.
FAU - Hochberger, Felix
AU  - Hochberger F
AD  - Department of Orthopedic Sports Medicine, Klinikum Rechts der Isar, Technical 
      University of Munich, 81675 Munich, Germany.
FAU - Holzl, Alexander
AU  - Holzl A
AUID- ORCID: 0000-0003-4013-0187
AD  - Orthopedic Department, Jena University Hospital, Campus Eisenberg, 07607 
      Eisenberg, Germany.
FAU - Bohle, Sabrina
AU  - Bohle S
AUID- ORCID: 0000-0002-6976-8953
AD  - Orthopedic Department, Jena University Hospital, Campus Eisenberg, 07607 
      Eisenberg, Germany.
FAU - Strube, Patrick
AU  - Strube P
AD  - Orthopedic Department, Jena University Hospital, Campus Eisenberg, 07607 
      Eisenberg, Germany.
LA  - eng
PT  - Journal Article
DEP - 20221030
PL  - Switzerland
TA  - J Pers Med
JT  - Journal of personalized medicine
JID - 101602269
PMC - PMC9692610
OTO - NOTNLM
OT  - facet joint capsule infiltration
OT  - low back pain
OT  - periradicular infiltration
OT  - radiculopathy
OT  - selective nerve block
COIS- The authors declare no conflict of interest.
EDAT- 2022/12/30 06:00
MHDA- 2022/12/30 06:01
PMCR- 2022/10/30
CRDT- 2022/12/29 04:24
PHST- 2022/09/30 00:00 [received]
PHST- 2022/10/16 00:00 [revised]
PHST- 2022/10/25 00:00 [accepted]
PHST- 2022/12/29 04:24 [entrez]
PHST- 2022/12/30 06:00 [pubmed]
PHST- 2022/12/30 06:01 [medline]
PHST- 2022/10/30 00:00 [pmc-release]
AID - jpm12111791 [pii]
AID - jpm-12-01791 [pii]
AID - 10.3390/jpm12111791 [doi]
PST - epublish
SO  - J Pers Med. 2022 Oct 30;12(11):1791. doi: 10.3390/jpm12111791.