PMID- 36583663 OWN - NLM STAT- MEDLINE DCOM- 20230112 LR - 20230112 IS - 1520-5118 (Electronic) IS - 0021-8561 (Linking) VI - 71 IP - 1 DP - 2023 Jan 11 TI - Exposure and Health Risk Assessment of Per- and Polyfluoroalkyl Substances in Crayfish from the Middle and Lower Reaches of the Yangtze River. PG - 825-835 LID - 10.1021/acs.jafc.2c06365 [doi] AB - Per- and polyfluoroalkyl substances (PFASs) are a novel class of emerging persistent organic pollutants (POPs) owing to their environmental persistence and bioaccumulation. Red swamp crayfish is a major source of exposure to PFASs, while the dietary intake of PFASs from crayfish is still unclear. We investigated the concentrations of PFASs in 130 batches of crayfish and 100 environmental samples from Middle and Lower Reaches of the Yangtze River Delta. Seven Perfluoroalkyl carboxylic acids (PFCAs), 3 Perfluoroalkyl sulfonates (PFSAs), and 6:2 Cl-PFESA were analyzed by ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). Meanwhile, PFASs exposure levels were examined concretely in four tissues of crayfish and different circulation links. The average daily intake (ADI) risk model was used to evaluate the human health risk of consuming crayfish and suggested that the risk of PFASs exposure is at a low level. FAU - Zhou, Mengxin AU - Zhou M AD - Key Laboratory for Deep Processing of Major Grain and Oil (The Chinese Ministry of Education), College of Food Science and Engineering, Wuhan Polytechnic University, Wuhan430023, Hubei, People's Republic of China. FAU - Zhao, Fang AU - Zhao F AD - Key Laboratory for Deep Processing of Major Grain and Oil (The Chinese Ministry of Education), College of Food Science and Engineering, Wuhan Polytechnic University, Wuhan430023, Hubei, People's Republic of China. FAU - Chen, Mengyuan AU - Chen M AD - Key Laboratory for Deep Processing of Major Grain and Oil (The Chinese Ministry of Education), College of Food Science and Engineering, Wuhan Polytechnic University, Wuhan430023, Hubei, People's Republic of China. FAU - Yu, QingQing AU - Yu Q AD - Key Laboratory for Deep Processing of Major Grain and Oil (The Chinese Ministry of Education), College of Food Science and Engineering, Wuhan Polytechnic University, Wuhan430023, Hubei, People's Republic of China. FAU - Liu, PinPin AU - Liu P AD - Key Laboratory for Deep Processing of Major Grain and Oil (The Chinese Ministry of Education), College of Food Science and Engineering, Wuhan Polytechnic University, Wuhan430023, Hubei, People's Republic of China. FAU - Wu, Kejia AU - Wu K AUID- ORCID: 0000-0002-0809-5628 AD - Key Laboratory for Deep Processing of Major Grain and Oil (The Chinese Ministry of Education), College of Food Science and Engineering, Wuhan Polytechnic University, Wuhan430023, Hubei, People's Republic of China. FAU - Wang, Hong AU - Wang H AD - Wuhan Institute for Food and Cosmetic Control, Wuhan430030, Hubei, China. FAU - Liu, Yan AU - Liu Y AD - Key Laboratory for Deep Processing of Major Grain and Oil (The Chinese Ministry of Education), College of Food Science and Engineering, Wuhan Polytechnic University, Wuhan430023, Hubei, People's Republic of China. FAU - Wang, Qiao AU - Wang Q AD - Key Laboratory for Deep Processing of Major Grain and Oil (The Chinese Ministry of Education), College of Food Science and Engineering, Wuhan Polytechnic University, Wuhan430023, Hubei, People's Republic of China. FAU - Liu, Xin AU - Liu X AUID- ORCID: 0000-0002-3498-4656 AD - Key Laboratory for Deep Processing of Major Grain and Oil (The Chinese Ministry of Education), College of Food Science and Engineering, Wuhan Polytechnic University, Wuhan430023, Hubei, People's Republic of China. FAU - Wu, Yongning AU - Wu Y AUID- ORCID: 0000-0001-6430-1302 AD - Key Laboratory for Deep Processing of Major Grain and Oil (The Chinese Ministry of Education), College of Food Science and Engineering, Wuhan Polytechnic University, Wuhan430023, Hubei, People's Republic of China. AD - NHC Key Laboratory of Food Safety Risk Assessment, Food Safety Research Unit (2019RU014) of Chinese Academy of Medical Science, China National Center for Food Safety Risk Assessment, Beijing100021, China. FAU - Gong, Zhiyong AU - Gong Z AD - Key Laboratory for Deep Processing of Major Grain and Oil (The Chinese Ministry of Education), College of Food Science and Engineering, Wuhan Polytechnic University, Wuhan430023, Hubei, People's Republic of China. LA - eng PT - Journal Article DEP - 20221230 PL - United States TA - J Agric Food Chem JT - Journal of agricultural and food chemistry JID - 0374755 RN - 0 (Water Pollutants, Chemical) RN - 0 (Fluorocarbons) RN - 0 (Alkanesulfonic Acids) SB - IM MH - Animals MH - Humans MH - *Water Pollutants, Chemical/analysis MH - Astacoidea MH - Rivers MH - Chromatography, Liquid MH - *Fluorocarbons/toxicity/analysis MH - Tandem Mass Spectrometry MH - Risk Assessment MH - Environmental Monitoring/methods MH - *Alkanesulfonic Acids/analysis OTO - NOTNLM OT - Crayfish OT - Per- and polyfluoroalkyl substances OT - Risk assessment OT - UPLC-MS/MS OT - exposure EDAT- 2022/12/31 06:00 MHDA- 2023/01/13 06:00 CRDT- 2022/12/30 10:06 PHST- 2022/12/31 06:00 [pubmed] PHST- 2023/01/13 06:00 [medline] PHST- 2022/12/30 10:06 [entrez] AID - 10.1021/acs.jafc.2c06365 [doi] PST - ppublish SO - J Agric Food Chem. 2023 Jan 11;71(1):825-835. doi: 10.1021/acs.jafc.2c06365. Epub 2022 Dec 30.