PMID- 36583841 OWN - NLM STAT- MEDLINE DCOM- 20230103 LR - 20230127 IS - 2300-9020 (Electronic) IS - 1644-387X (Linking) VI - 59 IP - 4 DP - 2022 Oct-Dec TI - Facial paralysis after intraoral anesthetic injection: A systematic review. PG - 617-627 LID - 10.17219/dmp/138910 [doi] AB - Many complications can occur after the injection of local intraoral anesthetics (ILIA) before dental intervention. Facial paralysis (FP) is one of these complications. The purpose of this study was to systematically analyze the association between ILIA and FP. A systematic review was carried out taking into account the methodology of the Cochrane Handbook for Systematic Reviews of Interventions and the PRISMA statement. The search strategy used "Palsy AND Facial" and "Paralysis AND Facial" as search terms. The ScienceDirect, PubMed and Scopus databases were searched using the "dentistry journal" filter. The inclusion criteria included studies describing FP after or during ILIA that were published in dental journals. The CAse REports (CARE) checklist was applied in evaluating the methodological quality of case reports. A total of 2,462 articles (algorithm) were identified. After reviewing titles and abstracts, 18 articles were deemed relevant taking into account the objectives of this study. Only 13 of them, after reading the full text, met the inclusion criteria and were analyzed. Case reports on 18 cases of FP were analyzed, 12 of which described the early development of FP (onset within 24 h) and 6 the late development (onset after 24 h). Acceptable compliance with CARE guidelines was observed in the included studies . Early FP CRs presented the effect of the administered anesthetic on the facial nerve, and the vascular effect of the vasoconstrictor included in the anesthetic formula, while more recent FP CRs focused on the reactivation of herpes simplex virus type 1 (HSV-1), human herpesvirus 6 (HHV-6) or varicella-zoster virus (VZV). FAU - Ferrer-Valdivia, Nicolas AU - Ferrer-Valdivia N AD - Dentistry Department, Faculty of Medicine and Dentistry, University of Antofagasta, Chile. AD - Biomedical Department, Faculty of Health Sciences, University of Antofagasta, Chile. FAU - Fernandez-Cordova, Melissa AU - Fernandez-Cordova M AD - Dentistry Department, Faculty of Medicine and Dentistry, University of Antofagasta, Chile. FAU - Herrera-Barraza, Victor AU - Herrera-Barraza V AD - Dentistry Department, Faculty of Medicine and Dentistry, University of Antofagasta, Chile. FAU - Araya, Jorge AU - Araya J AD - Medical Technology Department, Faculty of Health Sciences, University of Antofagasta, Chile. LA - eng PT - Journal Article PT - Review PT - Systematic Review PL - Poland TA - Dent Med Probl JT - Dental and medical problems JID - 101205669 RN - 0 (Anesthetics) SB - IM MH - Humans MH - *Facial Paralysis/chemically induced MH - *Herpesvirus 1, Human MH - Herpesvirus 3, Human/physiology MH - Face MH - *Anesthetics OTO - NOTNLM OT - Bell's palsy OT - anesthesia OT - facial paralysis OT - local anesthetics OT - systematic review EDAT- 2022/12/31 06:00 MHDA- 2023/01/04 06:00 CRDT- 2022/12/30 11:17 PHST- 2021/04/28 00:00 [received] PHST- 2021/06/10 00:00 [revised] PHST- 2021/06/14 00:00 [accepted] PHST- 2022/12/30 11:17 [entrez] PHST- 2022/12/31 06:00 [pubmed] PHST- 2023/01/04 06:00 [medline] AID - 10.17219/dmp/138910 [doi] PST - ppublish SO - Dent Med Probl. 2022 Oct-Dec;59(4):617-627. doi: 10.17219/dmp/138910.