PMID- 36587410
OWN - NLM
STAT- MEDLINE
DCOM- 20230103
LR  - 20230123
IS  - 1092-0684 (Electronic)
IS  - 1092-0684 (Linking)
VI  - 54
IP  - 1
DP  - 2023 Jan
TI  - Improvement following minimally invasive transforaminal lumbar interbody fusion 
      in patients aged 70 years or older compared with younger age groups.
PG  - E4
LID - 10.3171/2022.10.FOCUS22604 [doi]
AB  - OBJECTIVE: The goal of this study was to assess the outcomes of minimally 
      invasive transforaminal lumbar interbody fusion (MI-TLIF) in patients >/= 70 years 
      old and compare them to younger age groups. METHODS: This was a retrospective 
      study of data that were collected prospectively. Patients who underwent primary 
      single-level MI-TLIF were included and divided into 3 groups: age < 60, 60-69, 
      and >/= 70 years. The outcome measures were as follows: 1) patient-reported outcome 
      measures (PROMs) (i.e., visual analog scale [VAS] for back and leg pain, Oswestry 
      Disability Index [ODI], 12-Item Short-Form Health Survey Physical Component 
      Summary [SF-12 PCS]); 2) minimum clinically important difference (MCID) 
      achievement; 3) return to activities; 4) opioid discontinuation; 5) fusion rates; 
      and 6) complications/reoperations. RESULTS: A total of 147 patients (age < 60 
      years, 62; 60-69 years, 47; >/= 70 years, 38) were included. All the groups showed 
      significant improvements in all PROMs at the early (< 6 months) and late (>/= 6 
      months) time points and there was no significant difference between the groups. 
      Although MCID achievement rates for VAS leg and ODI were similar, they were lower 
      in the >/= 70-year-old patient group for VAS back and SF-12 PCS. Although the time 
      to MCID achievement for ODI and SF-12 PCS was similar, it was greater in the >/= 
      70-year-old patient group for VAS back and leg. There was no significant 
      difference between the groups in terms of return to activities, opioid 
      discontinuation, fusion rates, and complication/reoperation rates. CONCLUSIONS: 
      Although patients > 70 years of age may be less likely and/or take longer to 
      achieve MCID compared to their younger counterparts, they show an overall 
      significant improvement in PROMs, a similar likelihood of returning to activities 
      and discontinuing opioids, and comparable fusion and complication/reoperation 
      rates following MI-TLIF.
FAU - Shahi, Pratyush
AU  - Shahi P
AD  - 1Department of Spine Surgery, Hospital for Special Surgery, New York; and.
FAU - Dalal, Sidhant
AU  - Dalal S
AD  - 1Department of Spine Surgery, Hospital for Special Surgery, New York; and.
FAU - Shinn, Daniel
AU  - Shinn D
AD  - 1Department of Spine Surgery, Hospital for Special Surgery, New York; and.
FAU - Song, Junho
AU  - Song J
AD  - 1Department of Spine Surgery, Hospital for Special Surgery, New York; and.
FAU - Araghi, Kasra
AU  - Araghi K
AD  - 1Department of Spine Surgery, Hospital for Special Surgery, New York; and.
FAU - Melissaridou, Dimitra
AU  - Melissaridou D
AD  - 1Department of Spine Surgery, Hospital for Special Surgery, New York; and.
FAU - Sheha, Evan
AU  - Sheha E
AD  - 1Department of Spine Surgery, Hospital for Special Surgery, New York; and.
FAU - Dowdell, James
AU  - Dowdell J
AD  - 1Department of Spine Surgery, Hospital for Special Surgery, New York; and.
FAU - Iyer, Sravisht
AU  - Iyer S
AD  - 1Department of Spine Surgery, Hospital for Special Surgery, New York; and.
AD  - 2Department of Orthopedic Surgery, Weill Cornell Medical College, New York, New 
      York.
FAU - Qureshi, Sheeraz A
AU  - Qureshi SA
AD  - 1Department of Spine Surgery, Hospital for Special Surgery, New York; and.
AD  - 2Department of Orthopedic Surgery, Weill Cornell Medical College, New York, New 
      York.
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Neurosurg Focus
JT  - Neurosurgical focus
JID - 100896471
RN  - 0 (Analgesics, Opioid)
SB  - IM
MH  - Humans
MH  - Aged
MH  - *Lumbar Vertebrae/surgery
MH  - Treatment Outcome
MH  - Retrospective Studies
MH  - Analgesics, Opioid
MH  - *Spinal Fusion
MH  - Minimally Invasive Surgical Procedures
OTO - NOTNLM
OT  - MCID
OT  - PROMs
OT  - TLIF
OT  - age
OT  - complications
OT  - elderly
OT  - fusion rates
OT  - minimally invasive
OT  - outcomes
OT  - return to activities
EDAT- 2023/01/02 06:00
MHDA- 2023/01/04 06:00
CRDT- 2023/01/01 17:25
PHST- 2022/09/01 00:00 [received]
PHST- 2022/10/18 00:00 [accepted]
PHST- 2023/01/01 17:25 [entrez]
PHST- 2023/01/02 06:00 [pubmed]
PHST- 2023/01/04 06:00 [medline]
AID - 10.3171/2022.10.FOCUS22604 [doi]
PST - ppublish
SO  - Neurosurg Focus. 2023 Jan;54(1):E4. doi: 10.3171/2022.10.FOCUS22604.