PMID- 36588181
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230112
IS  - 2288-5919 (Print)
IS  - 2288-5943 (Electronic)
IS  - 2288-5919 (Linking)
VI  - 42
IP  - 1
DP  - 2023 Jan
TI  - Quantifying carotid stiffness in a pre-hypertensive population with ultrafast 
      ultrasound imaging.
PG  - 89-99
LID - 10.14366/usg.22039 [doi]
AB  - PURPOSE: The aim of this study was to assess carotid stiffening in a 
      pre-hypertensive (PHT) population using ultrafast pulse wave velocity (ufPWV). 
      METHODS: This study retrospectively enrolled 626 individuals who underwent 
      clinical interviews, serum tests, and assessments of the systolic blood pressure 
      (SBP), diastolic blood pressure (DBP), carotid intima-media thickness (cIMT), 
      pulse wave velocity-beginning of systole (PWV-BS), and pulse wave velocity-end of 
      systole (PWV-ES) between January 2017 and December 2021. The patients were 
      divided into three groups according to their blood pressure (BP)-normal BP (NBP): 
      SBP <130 mmHg and DBP <80 mmHg (n=215); PHT: 130 mmHg</=SBP<140 mmHg and/or 80 
      mmHg</=DBP<90 mmHg (n=119); hypertensive (HT): SBP >/=140 mmHg and/or DBP >/=90 mmHg 
      (n=292). Correlation analyses and comparisons were performed among the groups and 
      in the cIMT subgroups (cIMT >/=0.050 cm and <0.050 cm). RESULTS: cIMT and PWV-ES 
      significantly differed among the BP groups (P<0.05). The BP groups had similar 
      PWV-BS when cIMT <0.050 cm or cIMT >/=0.050 cm (all P>0.05). However, the NBP group 
      had a notably lower PWV-ES than the PHT (P<0.001 and P=0.024) and HT (all 
      P<0.001) groups in both cIMT categories, while the PWV-ES in the PHT group were 
      not significantly lower than in the HT group (all P>0.05). CONCLUSION: Carotid 
      morphological and biomechanical properties in the PHT group differed from those 
      in the NBP group. ufPWV could be used for an early evaluation of carotid 
      stiffening linked to pre-hypertension.
FAU - Ma, Xuehui
AU  - Ma X
AD  - Department of Ultrasound, Affiliated Hospital of Nanjing University of Chinese 
      Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing, China.
FAU - Zhu, Zhengqiu
AU  - Zhu Z
AD  - Department of Ultrasound, Affiliated Hospital of Nanjing University of Chinese 
      Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing, China.
FAU - Wang, Yinping
AU  - Wang Y
AD  - Department of Ultrasound, Affiliated Hospital of Nanjing University of Chinese 
      Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing, China.
FAU - Shen, Bixiao
AU  - Shen B
AD  - Department of Ultrasound, Affiliated Hospital of Nanjing University of Chinese 
      Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing, China.
FAU - Jiang, Xuezhong
AU  - Jiang X
AD  - Department of Ultrasound, Jiangsu Province Geriatric Hospital, Geriatric Hospital 
      of Nanjing Medical University, Nanjing, China.
FAU - Liu, Wenjun
AU  - Liu W
AD  - School of Mathematics and Statistics, Nanjing University of Information Science 
      and Technology, Nanjing, China.
FAU - Wu, Yiyun
AU  - Wu Y
AD  - Department of Ultrasound, Affiliated Hospital of Nanjing University of Chinese 
      Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing, China.
FAU - Zou, Chong
AU  - Zou C
AD  - Department of Cardiology, Affiliated Hospital of Nanjing University of Chinese 
      Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing, China.
AD  - Center of Good Clinical Practice, Affiliated Hospital of Nanjing University of 
      Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing, China.
FAU - Luan, Yun
AU  - Luan Y
AD  - Department of Ultrasound, Affiliated Hospital of Nanjing University of Chinese 
      Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing, China.
FAU - Gao, Hui
AU  - Gao H
AD  - Department of Ultrasound, Affiliated Hospital of Nanjing University of Chinese 
      Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing, China.
FAU - Huang, Hui
AU  - Huang H
AD  - Department of Ultrasound, Affiliated Hospital of Nanjing University of Chinese 
      Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing, China.
LA  - eng
GR  - 81901756/National Natural Science Foundation of China/
GR  - BE2019725/Key Research and Development Program of Jiangsu Province/
GR  - LK2021005/Research Project of Geriatric Health of Jiangsu Province/
GR  - YB2015020/Research Project of National Administration of Chinese Medicine/
PT  - Journal Article
DEP - 20220709
PL  - Korea (South)
TA  - Ultrasonography
JT  - Ultrasonography (Seoul, Korea)
JID - 101626019
PMC - PMC9816694
OTO - NOTNLM
OT  - Carotid
OT  - Pre-hypertensive
OT  - Pulse wave velocity
OT  - Ultrafast ultrasound imaging
OT  - Vascular stiffness
COIS- No potential conflict of interest relevant to this article was reported.
EDAT- 2023/01/03 06:00
MHDA- 2023/01/03 06:01
PMCR- 2023/01/01
CRDT- 2023/01/02 00:01
PHST- 2022/03/09 00:00 [received]
PHST- 2022/07/09 00:00 [accepted]
PHST- 2023/01/02 00:01 [entrez]
PHST- 2023/01/03 06:00 [pubmed]
PHST- 2023/01/03 06:01 [medline]
PHST- 2023/01/01 00:00 [pmc-release]
AID - usg.22039 [pii]
AID - usg-22039 [pii]
AID - 10.14366/usg.22039 [doi]
PST - ppublish
SO  - Ultrasonography. 2023 Jan;42(1):89-99. doi: 10.14366/usg.22039. Epub 2022 Jul 9.