PMID- 36593481 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230111 IS - 2326-0254 (Print) IS - 2326-0254 (Electronic) IS - 2326-0254 (Linking) VI - 10 IP - 1 DP - 2022 Dec 10 TI - Comprehensive comparisons of ocular biometry: A network-based big data analysis. PG - 1 LID - 10.1186/s40662-022-00320-3 [doi] LID - 1 AB - PURPOSE: To systematically compare and rank ocular measurements with optical and ultrasound biometers based on big data. METHODS: PubMed, Embase, the Cochrane Library and the US trial registry ( www. CLINICALTRIAL: gov ) were used to systematically search trials published up to October 22nd, 2020. We included comparative studies reporting the following parameters measured by at least two devices: axial length (AL), flattest meridian keratometry (Kf), steepest meridian keratometry (Ks), mean keratometry (Km), astigmatism (AST), astigmatism vectors J(0) and J(45), anterior chamber depth (ACD), aqueous depth (AQD), central corneal thickness (CCT), corneal diameter (CD) and lens thickness (LT). A network-based big data analysis was conducted using STATA version 13.1. RESULTS: Across 129 studies involving 17,181 eyes, 12 optical biometers and two ultrasound biometers (with both contact and immersion techniques) were identified. A network meta-analysis for AL and ACD measurements found that statistically significant differences existed when contact ultrasound biometry was compared with the optical biometers. There were no statistically significant differences among the four swept-source optical coherence tomography (SS-OCT) based devices (IOLMaster 700, OA-2000, Argos and ANTERION). As for Ks, Km and CD, statistically significant differences were found when the Pentacam AXL was compared with the IOLMaster and IOLMaster 500. There were statistically significant differences for CCT when the OA-2000 was compared to Pentacam AXL, IOLMaster 700, Lenstar, AL-Scan and Galilei G6. CONCLUSION: For AL and ACD, contact ultrasound biometry obtains the lower values compared with optical biometers. The Pentacam AXL achieves the lowest values for keratometry and CD. The smallest value for CCT measurement is found with the OA-2000. CI - (c) 2023. The Author(s). FAU - Yu, Jinjin AU - Yu J AD - Eye Institute and Department of Ophthalmology, Institute for Medical and Engineering Innovation, Eye & ENT Hospital, Fudan University; NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences, No. 19 Baoqing Road, Xuhui District, Shanghai, 200031, China. FAU - Wen, Daizong AU - Wen D AD - Quanzhou Aier Eye Hospital, Quanzhou, Fujian, China. FAU - Zhao, Jing AU - Zhao J AD - Eye Institute and Department of Ophthalmology, Institute for Medical and Engineering Innovation, Eye & ENT Hospital, Fudan University; NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences, No. 19 Baoqing Road, Xuhui District, Shanghai, 200031, China. AD - Shanghai Research Center of Ophthalmology and Optometry, Shanghai, China. FAU - Wang, Yiran AU - Wang Y AD - Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China. FAU - Feng, Ke AU - Feng K AD - Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China. FAU - Wan, Ting AU - Wan T AD - Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China. FAU - Savini, Giacomo AU - Savini G AD - IRCCS G.B. Bietti Foundation, Rome, Italy. FAU - McAlinden, Colm AU - McAlinden C AD - Department of Ophthalmology, Singleton Hospital, Swansea Bay University Health Board, Swansea, UK. FAU - Lin, Xuanqiao AU - Lin X AD - Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China. FAU - Niu, Lingling AU - Niu L AD - Eye Institute and Department of Ophthalmology, Institute for Medical and Engineering Innovation, Eye & ENT Hospital, Fudan University; NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences, No. 19 Baoqing Road, Xuhui District, Shanghai, 200031, China. AD - Shanghai Research Center of Ophthalmology and Optometry, Shanghai, China. FAU - Chen, Sisi AU - Chen S AD - Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China. FAU - Gao, Qingyi AU - Gao Q AD - Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China. FAU - Ning, Rui AU - Ning R AD - Eye Institute and Department of Ophthalmology, Institute for Medical and Engineering Innovation, Eye & ENT Hospital, Fudan University; NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences, No. 19 Baoqing Road, Xuhui District, Shanghai, 200031, China. FAU - Jin, Yili AU - Jin Y AD - Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China. FAU - Zhou, Xingtao AU - Zhou X AD - Eye Institute and Department of Ophthalmology, Institute for Medical and Engineering Innovation, Eye & ENT Hospital, Fudan University; NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences, No. 19 Baoqing Road, Xuhui District, Shanghai, 200031, China. doctzhouxingtao@163.com. AD - Shanghai Research Center of Ophthalmology and Optometry, Shanghai, China. doctzhouxingtao@163.com. FAU - Huang, Jinhai AU - Huang J AUID- ORCID: 0000-0001-9952-3175 AD - Eye Institute and Department of Ophthalmology, Institute for Medical and Engineering Innovation, Eye & ENT Hospital, Fudan University; NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences, No. 19 Baoqing Road, Xuhui District, Shanghai, 200031, China. vip999vip@163.com. AD - Shanghai Research Center of Ophthalmology and Optometry, Shanghai, China. vip999vip@163.com. LA - eng GR - 2021318/the EYE & ENT Hospital of Fudan University High-level Talents Program/ GR - SHDC2020CR1043B/Clinical Research Plan of SHDC/ GR - 2020-015/Project of Shanghai Xuhui District Science and Technology/ GR - 82271048/Project of National Natural Science Foundation of China/ GR - 22S11900200/Shanghai Science and Technology/ PT - Journal Article DEP - 20221210 PL - England TA - Eye Vis (Lond) JT - Eye and vision (London, England) JID - 101664982 PMC - PMC9808957 OTO - NOTNLM OT - Network-based big data analysis OT - Ocular biometric parameters OT - Optical biometry OT - Ultrasound biometry COIS- The authors declare that they have no competing interests. EDAT- 2023/01/03 06:00 MHDA- 2023/01/03 06:01 PMCR- 2022/12/10 CRDT- 2023/01/02 23:25 PHST- 2022/07/09 00:00 [received] PHST- 2022/11/19 00:00 [accepted] PHST- 2023/01/02 23:25 [entrez] PHST- 2023/01/03 06:00 [pubmed] PHST- 2023/01/03 06:01 [medline] PHST- 2022/12/10 00:00 [pmc-release] AID - 10.1186/s40662-022-00320-3 [pii] AID - 320 [pii] AID - 10.1186/s40662-022-00320-3 [doi] PST - epublish SO - Eye Vis (Lond). 2022 Dec 10;10(1):1. doi: 10.1186/s40662-022-00320-3.