PMID- 36599371
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230111
IS  - 1976-1902 (Print)
IS  - 1976-7846 (Electronic)
IS  - 1976-1902 (Linking)
VI  - 16
IP  - 6
DP  - 2022 Dec
TI  - Thoracolumbar Injury Classification and Severity Score Is Predictive of 
      Perioperative Adverse Events in Operatively Treated Thoracic and Lumbar 
      Fractures.
PG  - 848-856
LID - 10.31616/asj.2021.0231 [doi]
AB  - STUDY DESIGN: A retrospective cohort study of patients with surgically treated 
      thoracolumbar fractures. PURPOSE: This study aimed to describe the incidence of 
      adverse events (AEs) after surgical stabilization of thoracolumbar spine injuries 
      and to identify predictive factors for the occurrence of AEs. OVERVIEW OF 
      LITERATURE: Thoracolumbar spine fractures are frequently present in patients with 
      blunt trauma and are associated with significant morbidity. AEs can occur due to 
      the initial spinal injury or secondary to surgical treatment. There is a lack of 
      emphasis in the literature on the AEs that can occur after operative management 
      of thoracolumbar fractures. METHODS: We performed a retrospective review of 199 
      patients with surgically treated thoracolumbar fractures operated between January 
      2007 and January 2018. The potential risk factors for the development of AEs as 
      well as the development of common complications were evaluated by univariate 
      analysis, and a multivariate logistic regression analysis was performed to 
      identify independent risk factors predictive of the above. RESULTS: The overall 
      rate of AEs was 46.7%; 83 patients (41.7%) had nonsurgical AEs, whereas 24 
      (12.1%) had surgical adverse events. The most common AEs were urinary tract 
      infections in 43 patients (21.6%), and hospital-acquired pneumonia in 21 patients 
      (10.6%). On multivariate logistic regression, a Thoracolumbar Injury 
      Classification and Severity (TLICS) score of 8-10 (odds ratio [OR], 6.39; 95% 
      confidence interval [CI], 2.33-17.51), the presence of polytrauma (OR, 2.64; 95% 
      CI, 1.17-5.99), and undergoing open surgery (OR, 2.31; 95% CI, 1.09-4.88) were 
      significant risk factors for AEs. The absence of neurological deficit was 
      associated with a lower rate of AEs (OR, 0.47; 95% CI, 0.31-0.70). CONCLUSIONS: 
      This study suggests the presence of polytrauma, preoperative American Spinal 
      Injury Association score, and TLICS score are predictive of AEs in patients with 
      surgically treated thoracolumbar fractures. The results might also suggest a role 
      for minimally invasive surgical methods in reducing AEs in these patients.
FAU - Liu, Gabriel
AU  - Liu G
AD  - University Spine Centre, Department of Orthopaedic Surgery, National University 
      Hospital, Singapore.
FAU - Tan, Jiong Hao
AU  - Tan JH
AD  - University Spine Centre, Department of Orthopaedic Surgery, National University 
      Hospital, Singapore.
FAU - Kong, Jun Cheong
AU  - Kong JC
AD  - University Spine Centre, Department of Orthopaedic Surgery, National University 
      Hospital, Singapore.
FAU - Tan, Yong Hao Joel
AU  - Tan YHJ
AD  - University Spine Centre, Department of Orthopaedic Surgery, National University 
      Hospital, Singapore.
FAU - Kumar, Nishant
AU  - Kumar N
AD  - University Spine Centre, Department of Orthopaedic Surgery, National University 
      Hospital, Singapore.
FAU - Liang, Shen
AU  - Liang S
AD  - Biostatistics Unit, Yong Loo Lin School of Medicine, National University of 
      Singapore, Singapore.
FAU - Shawn, Seah Jing Sheng
AU  - Shawn SJS
AD  - Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
FAU - Ting, Chiu Shi
AU  - Ting CS
AD  - Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
FAU - Lim, Lau Leok
AU  - Lim LL
AD  - University Spine Centre, Department of Orthopaedic Surgery, National University 
      Hospital, Singapore.
FAU - Dennis, Hey Hwee Weng
AU  - Dennis HHW
AD  - University Spine Centre, Department of Orthopaedic Surgery, National University 
      Hospital, Singapore.
FAU - Kumar, Naresh
AU  - Kumar N
AD  - University Spine Centre, Department of Orthopaedic Surgery, National University 
      Hospital, Singapore.
FAU - Thambiah, Joseph
AU  - Thambiah J
AD  - University Spine Centre, Department of Orthopaedic Surgery, National University 
      Hospital, Singapore.
FAU - Wong, Hee-Kit
AU  - Wong HK
AD  - University Spine Centre, Department of Orthopaedic Surgery, National University 
      Hospital, Singapore.
LA  - eng
PT  - Journal Article
DEP - 20221229
PL  - Korea (South)
TA  - Asian Spine J
JT  - Asian spine journal
JID - 101314177
PMC - PMC9827217
OTO - NOTNLM
OT  - Fracture fixation
OT  - Intraoperative complications
OT  - Postoperative complications
OT  - Spinal fractures
COIS- No potential conflict of interest relevant to this article was reported.
EDAT- 2023/01/05 06:00
MHDA- 2023/01/05 06:01
PMCR- 2022/12/01
CRDT- 2023/01/04 19:05
PHST- 2021/06/28 00:00 [received]
PHST- 2022/01/03 00:00 [accepted]
PHST- 2023/01/05 06:00 [pubmed]
PHST- 2023/01/05 06:01 [medline]
PHST- 2023/01/04 19:05 [entrez]
PHST- 2022/12/01 00:00 [pmc-release]
AID - asj.2021.0231 [pii]
AID - asj-2021-0231 [pii]
AID - 10.31616/asj.2021.0231 [doi]
PST - ppublish
SO  - Asian Spine J. 2022 Dec;16(6):848-856. doi: 10.31616/asj.2021.0231. Epub 2022 Dec 
      29.