PMID- 36600301 OWN - NLM STAT- MEDLINE DCOM- 20230106 LR - 20230217 IS - 1749-7922 (Electronic) IS - 1749-7922 (Linking) VI - 18 IP - 1 DP - 2023 Jan 4 TI - Structured approach with primary and secondary survey for major trauma care: an overview of reviews. PG - 2 LID - 10.1186/s13017-022-00472-6 [doi] LID - 2 AB - BACKGROUND: A structured approach involves systematic management of trauma patients. We aim to conduct an overview of reviews about the clinical efficacy and safety of structured approach (i.e., primary and secondary survey) by guideline checklist compared to non-structured approach (i.e. clinical examination); moreover, routine screening whole-body computer tomography (WBCT) was compared to non-routine WBCT in patients with suspected major trauma. METHODS: We systematically searched MEDLINE (PubMed), EMBASE and Cochrane Database of Systematic Reviews up to 3 May 2022. Systematic reviews (SRs) that investigated the use of a structured approach compared to a non-structured approach were eligible. Two authors independently extracted data, managed the overlapping of primary studies belonging to the included SRs and calculated the corrected covered area (CCA). The certainty of evidence was assessed using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology. RESULTS: We included nine SRs investigating two comparisons in stable trauma patients: structured approach vs non-structured approach (n = 1) and routine WBCT vs non-routine WBCT (n = 8). The overlap of included primary studies was generally high across outcomes (CCA ranged between 20.85 and 42.86%) with some discrepancies in the directions of effects across reviews. The application of a structured approach by checklist may improve adherence to guidelines (e.g. Advanced Trauma Life Support) during resuscitation and might lead to a reduction in mortality among severely injured patients as compared to clinical examination (Adjusted OR 0.51; 95% CI 0.30-0.89; p = 0.018; low certainty of evidence). The use of routine WBCT seems to offer little to no effects in reducing mortality and time spent in emergency room or department, whereas non-routine WBCT seems to offer little to no effects in reducing radiation dose, intensive care unit length of stay (LOS) and hospital LOS (low-to-moderate certainty of evidence). CONCLUSIONS: The application of structured approach by checklist during trauma resuscitation may improve patient- and process-related outcomes. Including non-routine WBCT seems to offer the best trade-offs between benefits and harm. Clinicians should consider these findings in the light of their clinical context, the volume of patients in their facilities, the need for time management, and costs. CI - (c) 2023. The Author(s). FAU - Gianola, Silvia AU - Gianola S AD - Unit of Clinical Epidemiology, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy. silvia.gianola@grupposandonato.it. FAU - Bargeri, Silvia AU - Bargeri S AD - Unit of Clinical Epidemiology, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy. FAU - Biffi, Annalisa AU - Biffi A AD - National Centre for Healthcare Research and Pharmacoepidemiology,, University of Milano-Bicocca, Milan, Italy. AD - Unit of Biostatistics, Epidemiology and Public Health, Department of Statistics and Quantitative Methods, University of Milano-Bicocca, Milan, Italy. FAU - Cimbanassi, Stefania AU - Cimbanassi S AD - General Surgery and Trauma Team, ASST Grande Ospedale Metropolitano Niguarda, University of Milan, Piazza Ospedale Maggiore 3, 20162, Milan, Italy. FAU - D'Angelo, Daniela AU - D'Angelo D AD - Centro Nazionale per l Eccellenza Clinica, laQualita e la Sicurezza delle Cure, Istituto Superiore di Sanita, Rome, Italy. FAU - Coclite, Daniela AU - Coclite D AD - Centro Nazionale per l Eccellenza Clinica, laQualita e la Sicurezza delle Cure, Istituto Superiore di Sanita, Rome, Italy. FAU - Facchinetti, Gabriella AU - Facchinetti G AD - Centro Nazionale per l Eccellenza Clinica, laQualita e la Sicurezza delle Cure, Istituto Superiore di Sanita, Rome, Italy. FAU - Fauci, Alice Josephine AU - Fauci AJ AD - Centro Nazionale per l Eccellenza Clinica, laQualita e la Sicurezza delle Cure, Istituto Superiore di Sanita, Rome, Italy. FAU - Ferrara, Carla AU - Ferrara C AD - Centro Nazionale per l Eccellenza Clinica, laQualita e la Sicurezza delle Cure, Istituto Superiore di Sanita, Rome, Italy. FAU - Di Nitto, Marco AU - Di Nitto M AD - Centro Nazionale per l Eccellenza Clinica, laQualita e la Sicurezza delle Cure, Istituto Superiore di Sanita, Rome, Italy. FAU - Napoletano, Antonello AU - Napoletano A AD - Centro Nazionale per l Eccellenza Clinica, laQualita e la Sicurezza delle Cure, Istituto Superiore di Sanita, Rome, Italy. FAU - Punzo, Ornella AU - Punzo O AD - Centro Nazionale per l Eccellenza Clinica, laQualita e la Sicurezza delle Cure, Istituto Superiore di Sanita, Rome, Italy. FAU - Ranzato, Katya AU - Ranzato K AD - Gruppo MultiMedica, IRCCS MultiMedica, Sesto San Giovanni, Milan, Italy. FAU - Tratsevich, Alina AU - Tratsevich A AD - National Centre for Healthcare Research and Pharmacoepidemiology,, University of Milano-Bicocca, Milan, Italy. AD - Unit of Biostatistics, Epidemiology and Public Health, Department of Statistics and Quantitative Methods, University of Milano-Bicocca, Milan, Italy. FAU - Iannone, Primiano AU - Iannone P AD - Dipartimento di Medicina Interna, Azienda USL, Ospedale Maggiore, Largo Nigrisoli 2, 40133, Bologna, Italy. FAU - Castellini, Greta AU - Castellini G AD - Unit of Clinical Epidemiology, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy. FAU - Chiara, Osvaldo AU - Chiara O AD - General Surgery and Trauma Team, ASST Grande Ospedale Metropolitano Niguarda, University of Milan, Piazza Ospedale Maggiore 3, 20162, Milan, Italy. CN - Italian National Institute of Health guideline working group on Major Trauma LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Review DEP - 20230104 PL - England TA - World J Emerg Surg JT - World journal of emergency surgery : WJES JID - 101266603 SB - IM MH - Humans MH - Systematic Reviews as Topic MH - *Emergency Service, Hospital MH - *Tomography, X-Ray Computed/methods MH - Length of Stay MH - Injury Severity Score PMC - PMC9814503 OTO - NOTNLM OT - Advanced trauma life support care OT - Checklist OT - Diagnostic imaging OT - Emergency medicine OT - GRADE approach OT - Meta-analysis as topic OT - Structured approach OT - Systematic reviews COIS- The authors declare that they have no competing interests. EDAT- 2023/01/05 06:00 MHDA- 2023/01/07 06:00 PMCR- 2023/01/04 CRDT- 2023/01/04 23:38 PHST- 2022/11/09 00:00 [received] PHST- 2022/12/25 00:00 [accepted] PHST- 2023/01/04 23:38 [entrez] PHST- 2023/01/05 06:00 [pubmed] PHST- 2023/01/07 06:00 [medline] PHST- 2023/01/04 00:00 [pmc-release] AID - 10.1186/s13017-022-00472-6 [pii] AID - 472 [pii] AID - 10.1186/s13017-022-00472-6 [doi] PST - epublish SO - World J Emerg Surg. 2023 Jan 4;18(1):2. doi: 10.1186/s13017-022-00472-6.