PMID- 36603987
OWN - NLM
STAT- MEDLINE
DCOM- 20230109
LR  - 20230207
IS  - 1526-3231 (Electronic)
IS  - 0749-8063 (Linking)
VI  - 39
IP  - 2
DP  - 2023 Feb
TI  - Guidelines for Proper Reporting of Clinical Significance, Including Minimal 
      Clinically Important Difference, Patient Acceptable Symptomatic State, 
      Substantial Clinical Benefit, and Maximal Outcome Improvement.
PG  - 145-150
LID - S0749-8063(22)00512-6 [pii]
LID - 10.1016/j.arthro.2022.08.020 [doi]
AB  - Patient-reported outcome measures (PROM) need to be responsive, reliable, and 
      validated for the specific condition or treatment. PROMs also need to exhibit a 
      dose-dependent response across a diverse patient population, unlimited by floor 
      and ceiling effects. Statistically significant differences between compared 
      groups might not always represent clinically important differences. Measures of 
      clinical significance reflect a spectrum of patient satisfaction after an 
      intervention. A noticeable difference to the patient is assessed with minimal 
      clinically important difference (MCID), patient satisfaction by patient 
      acceptable symptomatic state (PASS), and a "considerable" improvement by 
      substantial clinical benefit (SCB). Clinical relevance measured by these 
      clinically significant outcomes (CSO) are limited by ceiling effects. Maximal 
      outcome improvement (MOI) might more accurately account for patients with higher 
      baseline or preoperative PROMs, thereby limiting ceiling effects. The acts of 
      measuring (and reporting) patient-centered endpoints may actually be of greater 
      importance than collecting objective clinician-measured data. As the old 
      surgeon's aphorism goes, "nothing ruins good results like good follow-up."
CI  - Copyright (c) 2022 Arthroscopy Association of North America. Published by Elsevier 
      Inc. All rights reserved.
FAU - Harris, Joshua D
AU  - Harris JD
AD  - Houston Methodist Orthopedics & Sports Medicine, Orthopedic Surgery, 6445 Main 
      St., Outpatient Center, Suite 2500, Houston, TX, 77030, U.S.A.
FAU - Brand, Jefferson C
AU  - Brand JC
AD  - Alexandria, Minnesota, U.S.A.. Electronic address: 
      jbrand@heartlandorthopedics.com.
FAU - Cote, Mark
AU  - Cote M
AD  - UConn Health, Farmington, Connecticut, U.S.A.
FAU - Waterman, Brian
AU  - Waterman B
AD  - Wake Forest University School of Medicine, Medical Center Boulevard, 
      Winston-Salem, NC, U.S.A.
FAU - Dhawan, Aman
AU  - Dhawan A
AD  - Penn State College of Medicine, Department of Orthopaedics and Rehabilitation, 
      Hershey, Pennsylvania, U.S.A.
LA  - eng
PT  - Journal Article
DEP - 20221207
PL  - United States
TA  - Arthroscopy
JT  - Arthroscopy : the journal of arthroscopic & related surgery : official 
      publication of the Arthroscopy Association of North America and the International 
      Arthroscopy Association
JID - 8506498
SB  - IM
MH  - Humans
MH  - *Minimal Clinically Important Difference
MH  - *Clinical Relevance
MH  - Treatment Outcome
MH  - Arthroscopy/methods
MH  - Patient Satisfaction
MH  - Patient Reported Outcome Measures
EDAT- 2023/01/06 06:00
MHDA- 2023/01/10 06:00
CRDT- 2023/01/05 21:03
PHST- 2022/07/04 00:00 [received]
PHST- 2022/07/31 00:00 [revised]
PHST- 2022/08/05 00:00 [accepted]
PHST- 2023/01/05 21:03 [entrez]
PHST- 2023/01/06 06:00 [pubmed]
PHST- 2023/01/10 06:00 [medline]
AID - S0749-8063(22)00512-6 [pii]
AID - 10.1016/j.arthro.2022.08.020 [doi]
PST - ppublish
SO  - Arthroscopy. 2023 Feb;39(2):145-150. doi: 10.1016/j.arthro.2022.08.020. Epub 2022 
      Dec 7.