PMID- 36613150 OWN - NLM STAT- MEDLINE DCOM- 20230110 LR - 20230220 IS - 1660-4601 (Electronic) IS - 1661-7827 (Print) IS - 1660-4601 (Linking) VI - 20 IP - 1 DP - 2023 Jan 1 TI - An Integrated System of Multifaceted Machine Learning Models to Predict If and When Hospital-Acquired Pressure Injuries (Bedsores) Occur. LID - 10.3390/ijerph20010828 [doi] LID - 828 AB - Hospital-Acquired Pressure Injury (HAPI), known as bedsore or decubitus ulcer, is one of the most common health conditions in the United States. Machine learning has been used to predict HAPI. This is insufficient information for the clinical team because knowing who would develop HAPI in the future does not help differentiate the severity of those predicted cases. This research develops an integrated system of multifaceted machine learning models to predict if and when HAPI occurs. Phase 1 integrates Genetic Algorithm with Cost-Sensitive Support Vector Machine (GA-CS-SVM) to handle the high imbalance HAPI dataset to predict if patients will develop HAPI. Phase 2 adopts Grid Search with SVM (GS-SVM) to predict when HAPI will occur for at-risk patients. This helps to prioritize who is at the highest risk and when that risk will be highest. The performance of the developed models is compared with state-of-the-art models in the literature. GA-CS-SVM achieved the best Area Under the Curve (AUC) (75.79 +/- 0.58) and G-mean (75.73 +/- 0.59), while GS-SVM achieved the best AUC (75.06) and G-mean (75.06). The research outcomes will help prioritize at-risk patients, allocate targeted resources and aid with better medical staff planning to provide intervention to those patients. FAU - Dweekat, Odai Y AU - Dweekat OY AUID- ORCID: 0000-0001-8710-2306 AD - Department of Systems Science and Industrial Engineering, Binghamton University, Binghamton, NY 13902, USA. FAU - Lam, Sarah S AU - Lam SS AD - Department of Systems Science and Industrial Engineering, Binghamton University, Binghamton, NY 13902, USA. FAU - McGrath, Lindsay AU - McGrath L AD - Wound Ostomy Continence Nursing, ChristianaCare Health System, Newark, DE 19718, USA. LA - eng PT - Journal Article DEP - 20230101 PL - Switzerland TA - Int J Environ Res Public Health JT - International journal of environmental research and public health JID - 101238455 SB - IM MH - Humans MH - *Pressure Ulcer/epidemiology/etiology MH - Machine Learning MH - Support Vector Machine MH - Area Under Curve MH - Hospitals PMC - PMC9820011 OTO - NOTNLM OT - bedsores OT - cost-sensitive support vector machine OT - genetic algorithm OT - hospital-acquired pressure injuries OT - integrated system OT - predictive model OT - pressure injuries OT - pressure ulcer COIS- The authors declare no conflict of interest. EDAT- 2023/01/09 06:00 MHDA- 2023/01/11 06:00 PMCR- 2023/01/01 CRDT- 2023/01/08 01:16 PHST- 2022/11/13 00:00 [received] PHST- 2022/12/21 00:00 [revised] PHST- 2022/12/27 00:00 [accepted] PHST- 2023/01/08 01:16 [entrez] PHST- 2023/01/09 06:00 [pubmed] PHST- 2023/01/11 06:00 [medline] PHST- 2023/01/01 00:00 [pmc-release] AID - ijerph20010828 [pii] AID - ijerph-20-00828 [pii] AID - 10.3390/ijerph20010828 [doi] PST - epublish SO - Int J Environ Res Public Health. 2023 Jan 1;20(1):828. doi: 10.3390/ijerph20010828.