PMID- 36620811
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230111
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 14
IP  - 12
DP  - 2022 Dec
TI  - A Case of Gastric Mucormycosis in a 21-Year-Old Patient With Hemophagocytic 
      Lymphohistiocytosis.
PG  - e32215
LID - 10.7759/cureus.32215 [doi]
LID - e32215
AB  - Mucormycosis is an angioinvasive, opportunistic infection. Diabetes Mellitus and 
      immunosuppression are the most common risk factors for fungal infection. Without 
      prompt treatment, the infection can be fatal. A 21-year-old male patient 
      presented with gastritis-like symptoms refractory to proton pump inhibitor (PPI) 
      therapy. He recently received treatment for Hemophagocytic Lymphohistiocytosis 
      (HLH), confirmed by bone marrow biopsy and fungal sinusitis. 
      Esophagogastroduodenoscopy (EGD) revealed extensive gastric involvement by 
      Mucormycosis. The patient was given antifungal drugs and a resection of necrotic 
      stomach tissue. Gastric mucormycosis is a rare presentation of the angioinvasive 
      fungus. The patient's young age and lack of distinguishing risk factors such as 
      diabetes or immunosuppression are also unusual. Furthermore, the patient's unique 
      presentation with gastric mucormycosis compounded by a recent diagnosis of 
      Hemophagocytosis lymphohistiocytosis produces a valuable case study in 
      management.
CI  - Copyright (c) 2022, Noor et al.
FAU - Noor, Aysha
AU  - Noor A
AD  - Medicine, Shifa Tameer-E-Millat University Shifa College of Medicine, Islamabad, 
      PAK.
FAU - Anwar, Savera
AU  - Anwar S
AD  - Medicine, Shifa Tameer-E-Millat University Shifa College of Medicine, islamaabad, 
      PAK.
FAU - Wali, Hadia
AU  - Wali H
AD  - Otolaryngology - Head and Neck Surgery, Shifa International Hospital, Islamabad, 
      PAK.
FAU - Ansari, Shayan S
AU  - Ansari SS
AD  - Otolaryngology - Head and Neck Surgery, Shifa International Hospital, Islamabad, 
      PAK.
FAU - Ali, Zafar
AU  - Ali Z
AD  - Pathology, Shifa International Hospital, Islamabad, PAK.
AD  - Pathology, Shifa Tameer-E-Millat University Shifa College of Medicine, Islamabad, 
      PAK.
LA  - eng
PT  - Case Reports
DEP - 20221205
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC9812033
OTO - NOTNLM
OT  - functional endoscopic sinus surgery (fess)
OT  - fungal rhino sinusitis
OT  - gastric biopsy
OT  - gastrointestinal mucormycosis
OT  - hemetemesis
COIS- The authors have declared that no competing interests exist.
EDAT- 2023/01/10 06:00
MHDA- 2023/01/10 06:01
PMCR- 2022/12/05
CRDT- 2023/01/09 04:19
PHST- 2022/12/05 00:00 [accepted]
PHST- 2023/01/09 04:19 [entrez]
PHST- 2023/01/10 06:00 [pubmed]
PHST- 2023/01/10 06:01 [medline]
PHST- 2022/12/05 00:00 [pmc-release]
AID - 10.7759/cureus.32215 [doi]
PST - epublish
SO  - Cureus. 2022 Dec 5;14(12):e32215. doi: 10.7759/cureus.32215. eCollection 2022 
      Dec.