PMID- 36623384
OWN - NLM
STAT- MEDLINE
DCOM- 20230123
LR  - 20230123
IS  - 1879-2448 (Electronic)
IS  - 0043-1354 (Linking)
VI  - 230
DP  - 2023 Feb 15
TI  - Nonmonotonic effect of CuO nanoparticles on medium-chain carboxylates production 
      from waste activated sludge.
PG  - 119545
LID - S0043-1354(22)01490-7 [pii]
LID - 10.1016/j.watres.2022.119545 [doi]
AB  - The growing applications of CuO nanoparticles (NPs) in industrial and agriculture 
      has increased their concentrations in wastewater and subsequently accumulated in 
      waste activated sludge (WAS), raising concerns about their impact on 
      reutilization of WAS, especially on the medium-chain carboxylates (MCCs) 
      production from anaerobic fermentation of WAS. Here we showed that CuO NPs at 
      10-50 mg/g-TS can significantly inhibit MCCs production, and reactive oxygen 
      species generation was revealed to be the key factor linked to the phenomena. At 
      lower CuO NPs concentrations (0.5-2.5 mg/g-TS), however, MCCs production was 
      enhanced, with a maximum level of 37% compared to the control. The combination of 
      molecular approaches and metaproteomic analysis revealed that although low dosage 
      CuO NPs (2.5 mg/g-TS) weakly inhibited chain elongation process, they displayed 
      contributive characteristics both in WAS solubilization and transport/metabolism 
      of carbohydrate. These results demonstrated that the complex microbial processes 
      for MCCs production in the anaerobic fermentation of WAS can be affected by CuO 
      NPs in a dosage-dependent manner via regulating microbial protein expression 
      level. Our findings can provide new insights into the influence of CuO NPs on 
      anaerobic fermentation process and shed light on the treatment option for the 
      resource utilization of CuO NPs polluted WAS.
CI  - Copyright (c) 2022 Elsevier Ltd. All rights reserved.
FAU - Liu, Chao
AU  - Liu C
AD  - Institute of Environmental Research at Greater Bay Area, Key Laboratory for Water 
      Quality and Conservation of the Pearl River Delta, Ministry of Education, 
      Guangzhou University, Guangzhou 510006, P R China.
FAU - Wang, Haiqing
AU  - Wang H
AD  - School of Environmental Science and Engineering, Shandong University, Jinan 
      250100, PR China.
FAU - Usman, Muhammad
AU  - Usman M
AD  - Bioproducts Science & Engineering Laboratory (BSEL), Department of Biological 
      Systems Engineering, Washington State University (WSU), Richland, WA, USA.
FAU - Ji, Mengyuan
AU  - Ji M
AD  - Department of Biology, University of Padua, Via U. Bassi 58/b, 35121 Padova, 
      Italy.
FAU - Sha, Jun
AU  - Sha J
AD  - Institute of Environmental Research at Greater Bay Area, Key Laboratory for Water 
      Quality and Conservation of the Pearl River Delta, Ministry of Education, 
      Guangzhou University, Guangzhou 510006, P R China.
FAU - Liang, Zhenda
AU  - Liang Z
AD  - Institute of Environmental Research at Greater Bay Area, Key Laboratory for Water 
      Quality and Conservation of the Pearl River Delta, Ministry of Education, 
      Guangzhou University, Guangzhou 510006, P R China.
FAU - Zhu, Lishan
AU  - Zhu L
AD  - Institute of Environmental Research at Greater Bay Area, Key Laboratory for Water 
      Quality and Conservation of the Pearl River Delta, Ministry of Education, 
      Guangzhou University, Guangzhou 510006, P R China.
FAU - Zhou, Li
AU  - Zhou L
AD  - Institute of Environmental Research at Greater Bay Area, Key Laboratory for Water 
      Quality and Conservation of the Pearl River Delta, Ministry of Education, 
      Guangzhou University, Guangzhou 510006, P R China. Electronic address: 
      zhoul@gzhu.edu.cn.
FAU - Yan, Bing
AU  - Yan B
AD  - Institute of Environmental Research at Greater Bay Area, Key Laboratory for Water 
      Quality and Conservation of the Pearl River Delta, Ministry of Education, 
      Guangzhou University, Guangzhou 510006, P R China. Electronic address: 
      drbingyan@yahoo.com.
LA  - eng
PT  - Journal Article
DEP - 20221229
PL  - England
TA  - Water Res
JT  - Water research
JID - 0105072
RN  - 0 (Sewage)
RN  - V1XJQ704R4 (cupric oxide)
RN  - 789U1901C5 (Copper)
SB  - IM
MH  - *Sewage
MH  - Waste Disposal, Fluid/methods
MH  - *Nanoparticles/analysis
MH  - Copper
OTO - NOTNLM
OT  - Anaerobic fermentation
OT  - CuO nanoparticles
OT  - Medium chain carboxylate
OT  - Metaproteomic analysis
OT  - Waste activated sludge
COIS- Declaration of Competing Interest The authors declare no competing interest.
EDAT- 2023/01/10 06:00
MHDA- 2023/01/24 06:00
CRDT- 2023/01/09 18:09
PHST- 2022/06/07 00:00 [received]
PHST- 2022/12/18 00:00 [revised]
PHST- 2022/12/27 00:00 [accepted]
PHST- 2023/01/10 06:00 [pubmed]
PHST- 2023/01/24 06:00 [medline]
PHST- 2023/01/09 18:09 [entrez]
AID - S0043-1354(22)01490-7 [pii]
AID - 10.1016/j.watres.2022.119545 [doi]
PST - ppublish
SO  - Water Res. 2023 Feb 15;230:119545. doi: 10.1016/j.watres.2022.119545. Epub 2022 
      Dec 29.