PMID- 36633737
OWN - NLM
STAT- MEDLINE
DCOM- 20230511
LR  - 20240309
IS  - 1573-0832 (Electronic)
IS  - 0301-486X (Linking)
VI  - 188
IP  - 1-2
DP  - 2023 Apr
TI  - Paracoccidioides and Paracoccidioidomycosis in the 21st Century.
PG  - 129-133
LID - 10.1007/s11046-022-00704-y [doi]
AB  - Paracoccidioidomycosis (PCM) defines a broad spectrum of human and animal 
      diseases caused by Paracoccidioides species (Onygenales). In the twenty-first 
      century, Paracoccidioides advanced from a monotypic taxon to a genus that harbors 
      seven species, including P. brasiliensis sensu stricto, P. americana, P. 
      restrepiensis, P. venezuelensis, P. lutzii, P. loboi, and P. cetii. Classic PCM, 
      acquired upon inhalation of propagules from P. brasiliensis sensu stricto, P. 
      americana, P. restrepiensis, P. venezuelensis, and P. lutzii, affects the human 
      lungs and may progress to systemic granulomatous disease with tegumentary and 
      visceral involvement. On the other hand, PCM loboi and PCM ceti caused by the 
      unculturable P. loboi and P. cetii are subcutaneous mycoses, typically observed 
      as keloid lesions in humans and dolphins. Such heterogeneity highlights the 
      importance of recognizing species boundaries in Paracoccidioides to gain insights 
      into the ecology, evolution, clinical features, and mitigation strategies to 
      tackle the advance of PCM.
CI  - (c) 2023. The Author(s), under exclusive licence to Springer Nature B.V.
FAU - Rodrigues, Anderson Messias
AU  - Rodrigues AM
AUID- ORCID: 0000-0003-0891-4563
AD  - Department of Microbiology, Immunology, and Parasitology, Discipline of Cellular 
      Biology, Federal University of Sao Paulo (UNIFESP), Sao Paulo, 04023062, Brazil. 
      amrodrigues@unifesp.br.
AD  - Department of Medicine, Discipline of Infectious Diseases, Federal University of 
      Sao Paulo (UNIFESP), Sao Paulo, 04023062, Brazil. amrodrigues@unifesp.br.
FAU - Hagen, Ferry
AU  - Hagen F
AUID- ORCID: 0000-0002-5622-1916
AD  - Department of Medical Mycology, Westerdijk Fungal Biodiversity Institute, 
      Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands.
AD  - Department of Medical Microbiology, University Medical Center Utrecht, 
      Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands.
AD  - Institute for Biodiversity and Ecosystem Dynamics (IBED), University of 
      Amsterdam, Amsterdam, The Netherlands.
FAU - Puccia, Rosana
AU  - Puccia R
AUID- ORCID: 0000-0002-3332-0487
AD  - Department of Microbiology, Immunology, and Parasitology, Discipline of Cellular 
      Biology, Federal University of Sao Paulo (UNIFESP), Sao Paulo, 04023062, Brazil.
FAU - Hahn, Rosane Christine
AU  - Hahn RC
AUID- ORCID: 0000-0003-2686-8193
AD  - Medical Mycology Laboratory/Investigation, Faculty of Medicine, Federal 
      University of Mato Grosso, Cuiaba, MT, 78060900, Brazil.
AD  - Julio Muller Hospital, EBSERH, Cuiaba, MT, Brazil.
FAU - de Camargo, Zoilo Pires
AU  - de Camargo ZP
AUID- ORCID: 0000-0002-2971-7983
AD  - Department of Microbiology, Immunology, and Parasitology, Discipline of Cellular 
      Biology, Federal University of Sao Paulo (UNIFESP), Sao Paulo, 04023062, Brazil.
AD  - Department of Medicine, Discipline of Infectious Diseases, Federal University of 
      Sao Paulo (UNIFESP), Sao Paulo, 04023062, Brazil.
LA  - eng
GR  - 2017/27265-5/FAPESP/
GR  - 433276/2018-5/CNPq/
GR  - 304902/2020-9/CNPq/
PT  - Journal Article
PT  - Review
DEP - 20230112
PL  - Netherlands
TA  - Mycopathologia
JT  - Mycopathologia
JID - 7505689
SB  - IM
MH  - Animals
MH  - Humans
MH  - Dolphins/microbiology
MH  - Genomics
MH  - *Paracoccidioides/classification/genetics/isolation & purification
MH  - *Paracoccidioidomycosis/diagnosis/epidemiology/immunology/microbiology
MH  - Phylogeny
OTO - NOTNLM
OT  - Diagnosis
OT  - Epidemiology
OT  - Paracoccidioides americana
OT  - Paracoccidioides brasiliensis
OT  - Paracoccidioides cetii, Paracoccidioides lutzii
OT  - Paracoccidioides loboi
OT  - Paracoccidioides restrepiensis
OT  - Paracoccidioides venezuelensis
OT  - Systemic mycosis
EDAT- 2023/01/13 06:00
MHDA- 2023/05/11 06:42
CRDT- 2023/01/12 11:18
PHST- 2022/10/04 00:00 [received]
PHST- 2022/12/16 00:00 [accepted]
PHST- 2023/05/11 06:42 [medline]
PHST- 2023/01/13 06:00 [pubmed]
PHST- 2023/01/12 11:18 [entrez]
AID - 10.1007/s11046-022-00704-y [pii]
AID - 10.1007/s11046-022-00704-y [doi]
PST - ppublish
SO  - Mycopathologia. 2023 Apr;188(1-2):129-133. doi: 10.1007/s11046-022-00704-y. Epub 
      2023 Jan 12.