PMID- 36642070
OWN - NLM
STAT- MEDLINE
DCOM- 20230405
LR  - 20230411
IS  - 1421-976X (Electronic)
IS  - 0008-6568 (Linking)
VI  - 57
IP  - 1
DP  - 2023
TI  - Dentine Mineral Changes Induced by Polyalkenoate Cements after Different 
      Selective Caries Removal Techniques: An in vitro Study.
PG  - 21-31
LID - 10.1159/000529101 [doi]
AB  - This study aimed at evaluating the mineral variation induced by polyalkenoate 
      cements in residual dentine after different caries removal methods. Ten extracted 
      sound molars were selected, and five cavities were prepared on the occlusal 
      surface of each specimen. Carious lesions were generated using a microbial 
      protocol, while the caries removal was performed using bur, hand excavator, or 
      two papain-based chemo-mechanical agents. One cavity was left unexcavated in each 
      tooth. Cavities were restored using a zinc polycarboxylate cement (ZPC; n = 25), 
      or a glass ionomer cement (GIC) was used (n = 25). Subsequently, the specimens 
      were stored under simulated pulpal pressure for 45 days. Micro-CT scanning was 
      performed after caries formation, removal, and restoration. Cavity volumes (mm3) 
      and mineral density (MD) changes were calculated. Remineralisation ability was 
      investigated by scanning electron microscopy (SEM) and Fourier-transformed 
      infrared spectroscopy (FTIR). Statistical analysis was performed (5% significance 
      level). Baseline caries, cavity volume, and MD increase after caries removal were 
      similar to all excavation groups (p > 0.05). MD was higher in ZPC compared to GIC 
      (p < 0.05). SEM revealed that the chemo-mechanical techniques produced a smoother 
      dentine surface compared to mechanical methods. FTIR showed silicon-based 
      minerals in GIC-treated dentine, while ZPC-treated presented mineral deposits 
      characterised by amorphous calcium phosphate. In both cases, the presence of 
      carbonates was detected on dentine surfaces. All caries removal techniques 
      performed similarly in terms of carious dentine excavation. ZPC can be used as 
      dentine replacement material after caries removal as it may induce higher MD 
      increase in residual dentine via deposition of calcium phosphates, compared to 
      GIC.
CI  - (c) 2023 S. Karger AG, Basel.
FAU - Pires, Paula Maciel
AU  - Pires PM
AD  - Department of Pediatric Dentistry and Orthodontics, Universidade Federal do Rio 
      de Janeiro, Rio de Janeiro, Brazil, paulinha_pmp@hotmail.com.
AD  - Dental Biomaterials & Minimally Invasive Dentistry, Department of Dentistry, 
      University CEU Cardenal Herrera, Valencia, Spain, paulinha_pmp@hotmail.com.
FAU - Nunes Monteiro, Amanda Souza
AU  - Nunes Monteiro AS
AD  - Department of Pediatric Dentistry and Orthodontics, Universidade Federal do Rio 
      de Janeiro, Rio de Janeiro, Brazil.
FAU - Helena de Accioly Costa, Paula
AU  - Helena de Accioly Costa P
AD  - Department of Pediatric Dentistry and Orthodontics, Universidade Federal do Rio 
      de Janeiro, Rio de Janeiro, Brazil.
FAU - Silva, Aline Saddock
AU  - Silva AS
AD  - Laboratory of Nuclear Instrumentation, Universidade Federal do Rio de Janeiro, 
      Rio de Janeiro, Brazil.
FAU - Lopes, Ricardo Tadeu
AU  - Lopes RT
AD  - Laboratory of Nuclear Instrumentation, Universidade Federal do Rio de Janeiro, 
      Rio de Janeiro, Brazil.
FAU - Yoshihara, Kumiko
AU  - Yoshihara K
AD  - National Institute of Advanced Industrial Science and Technology (AIST), Health 
      Research Institute, Okayama, Japan.
FAU - Sauro, Salvatore
AU  - Sauro S
AD  - Dental Biomaterials & Minimally Invasive Dentistry, Department of Dentistry, 
      University CEU Cardenal Herrera, Valencia, Spain.
FAU - de Almeida Neves, Aline
AU  - de Almeida Neves A
AD  - Department of Pediatric Dentistry and Orthodontics, Universidade Federal do Rio 
      de Janeiro, Rio de Janeiro, Brazil.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20230114
PL  - Switzerland
TA  - Caries Res
JT  - Caries research
JID - 0103374
RN  - 0 (Glass Ionomer Cements)
RN  - 0 (Minerals)
SB  - IM
MH  - Humans
MH  - *Glass Ionomer Cements/therapeutic use
MH  - Dental Caries Susceptibility
MH  - Minerals
MH  - *Dental Caries/therapy/pathology
MH  - Dentin/pathology
OTO - NOTNLM
OT  - Dental caries
OT  - Dentin
OT  - Glass ionomer cements
OT  - Papain
OT  - Polycarboxylate cement
EDAT- 2023/01/16 06:00
MHDA- 2023/04/05 06:42
CRDT- 2023/01/15 18:20
PHST- 2022/05/23 00:00 [received]
PHST- 2023/01/08 00:00 [accepted]
PHST- 2023/04/05 06:42 [medline]
PHST- 2023/01/16 06:00 [pubmed]
PHST- 2023/01/15 18:20 [entrez]
AID - 000529101 [pii]
AID - 10.1159/000529101 [doi]
PST - ppublish
SO  - Caries Res. 2023;57(1):21-31. doi: 10.1159/000529101. Epub 2023 Jan 14.