PMID- 36647557 OWN - NLM STAT- MEDLINE DCOM- 20230501 LR - 20230817 IS - 2045-7634 (Electronic) IS - 2045-7634 (Linking) VI - 12 IP - 7 DP - 2023 Apr TI - Piloting HealthScore: Feasibility and acceptability of a clinically integrated health coaching program for people living with cancer. PG - 8804-8814 LID - 10.1002/cam4.5625 [doi] AB - BACKGROUND: Cancer supportive care interventions often have limited generalizability, goal misalignment, and high costs. We developed and piloted a health coaching intervention, UNC HealthScore, in patients undergoing cancer treatment (ClinicalTrials.gov identifier NCT04923997). We present feasibility, acceptability, and preliminary outcome data. METHODS: HealthScore is a six-month, theory-based, multicomponent intervention delivered through participant-driven coaching sessions. For the pilot study, participants were provided a Fitbit, responded to weekly symptom and physical function digital surveys, and met with a health coach weekly to develop and monitor goals. Coaching notes were discussed in weekly interdisciplinary team meetings and provided back to the treating oncology team. Symptom alerts were monitored and triaged through a study resource nurse to relevant supportive care services. Feasibility was determined based on intervention enrollment and completion. Acceptability was based on satisfaction with coaching and Fitbit-wearing and was informed by semistructured exit interviews. Outcomes evaluated for signs of improvement included several PROMIS (Patient-Reported Outcomes Measurement Information System) measures, including the primary intervention target, physical function. RESULTS: From May 2020 to March 2022, 50 participants completed the single-arm pilot. Feasibility was high: 66% enrolled and 71% completed the full intervention. Participants reported an average of 4.8 and 4.7 (out of 5) on the acceptability of coaching calls and using the Fitbit, respectively. Physical function scores rose 3.1 points (SE = 1.1) from baseline to 3 months, and 4.3 (SE = 1.0) from baseline to 6 months, above established minimal clinically important difference (MCID). Improvements above MCID were also evident in anxiety and depression, and smaller improvements were demonstrated for emotional support, social isolation, cognitive function, symptom burden, and self-efficacy. DISCUSSION: HealthScore shows feasibility, acceptability, and promising preliminary outcomes. Randomized studies are underway to determine the efficacy of preserving physical function in patients with advanced cancer. CI - (c) 2023 The Authors. Cancer Medicine published by John Wiley & Sons Ltd. FAU - Wood, William A AU - Wood WA AD - Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. AD - Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. FAU - Bailey, Carly AU - Bailey C AD - Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. FAU - Castrogivanni, Brianna AU - Castrogivanni B AD - Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. FAU - Mehedint, Diana AU - Mehedint D AD - Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA. FAU - Bryant, Ashley Leak AU - Bryant AL AD - Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. AD - School of Nursing, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. FAU - Lavin, Kyle AU - Lavin K AD - Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. AD - Department of Psychiatry, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. FAU - Tan, Xianming AU - Tan X AD - Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. AD - Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. FAU - Richardson, Jaime AU - Richardson J AD - Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. FAU - Qian, Yiqing AU - Qian Y AD - Department of Health Behavior, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. FAU - Tan, Kelly R AU - Tan KR AD - Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. FAU - Kent, Erin E AU - Kent EE AUID- ORCID: 0000-0003-2503-2191 AD - Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. AD - Department of Health Policy and Management, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. LA - eng SI - ClinicalTrials.gov/NCT04923997 GR - T32 CA116339/CA/NCI NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural DEP - 20230116 PL - United States TA - Cancer Med JT - Cancer medicine JID - 101595310 SB - IM MH - Humans MH - Pilot Projects MH - Feasibility Studies MH - *Mentoring MH - *Neoplasms/therapy MH - Health Promotion PMC - PMC10134320 OTO - NOTNLM OT - cancer OT - health coaching OT - physical function OT - pilot OT - self-efficacy OT - symptom management OT - telehealth COIS- WAW reports research funding from Pfizer and Genentech, consulting for Teladoc, and is an advisor with equity for Koneksa Health. EDAT- 2023/01/18 06:00 MHDA- 2023/05/01 06:41 PMCR- 2023/01/16 CRDT- 2023/01/17 01:52 PHST- 2022/12/13 00:00 [revised] PHST- 2022/09/08 00:00 [received] PHST- 2023/01/03 00:00 [accepted] PHST- 2023/05/01 06:41 [medline] PHST- 2023/01/18 06:00 [pubmed] PHST- 2023/01/17 01:52 [entrez] PHST- 2023/01/16 00:00 [pmc-release] AID - CAM45625 [pii] AID - 10.1002/cam4.5625 [doi] PST - ppublish SO - Cancer Med. 2023 Apr;12(7):8804-8814. doi: 10.1002/cam4.5625. Epub 2023 Jan 16.