PMID- 36653902
OWN - NLM
STAT- MEDLINE
DCOM- 20230609
LR  - 20230612
IS  - 1552-4175 (Electronic)
IS  - 1099-8004 (Linking)
VI  - 25
IP  - 3
DP  - 2023 Jul
TI  - Electrocardiogram Abnormalities Associated With Metabolic Syndrome: The Hispanic 
      Community Health Study/Study of Latinos.
PG  - 469-479
LID - 10.1177/10998004231152849 [doi]
AB  - BACKGROUND: Metabolic syndrome (MetS) is a prognostic cluster of physiologic risk 
      factors that may develop into cardiovascular disease (CVD) and type 2 diabetes 
      mellitus (T2DM). Electrocardiogram abnormalities (ECGA) can be instrumental in 
      identifying the early stages of disease and may be associated with MetS in 
      Hispanic Americans. OBJECTIVE: To explore the relationships between MetS and 
      major and minor ECGA in the Hispanic population (Hypothesis 1) and determine 
      whether gender-ethnic subgroups moderate these relationships (Hypothesis 2). 
      METHODS: This secondary data analysis was conducted using large-scale data from 
      the cohort study Hispanic Community Health Study/Study of Latinos (N = 13,628; 
      59% women and 41% men). Major ECGA encompassed 9 abnormalities including 
      pathologic Q waves and left ventricular hypertrophy. Minor ECGA were tested 
      independently of major ECGA. MetS was classified into 4 categories delineating 
      metabolic abnormalities and related medication use. Multinomial logistic 
      regression and Hayes' PROCESS macro were used for statistical analysis. RESULTS: 
      Major ECGA were significantly associated with the presence of MetS and/or related 
      medication use, whereas minor ECGA abnormalities were associated with MetS for 
      participants who also took MetS-related medications only. Gender moderated the 
      association between MetS and minor ECGA such that women with minor ECGA had a 
      higher likelihood of MetS when compared to men. CONCLUSIONS: Findings suggest 
      that early recognition and associated treatment of major and minor ECGA can be 
      important to prevent MetS and further morbidities in the Hispanic population.
FAU - Richard, Shannon L
AU  - Richard SL
AUID- ORCID: 0000-0003-2841-9156
AD  - University of Nevada, Las Vegas, NV, USA.
FAU - Feng, Du
AU  - Feng D
AUID- ORCID: 0000-0003-0333-2687
AD  - University of Nevada, Las Vegas, NV, USA.
FAU - Kim, Jinyoung
AU  - Kim J
AD  - University of Nevada, Las Vegas, NV, USA.
FAU - Tran, Dieu-My T
AU  - Tran DT
AUID- ORCID: 0000-0001-9956-8664
AD  - University of Nevada, Las Vegas, NV, USA.
FAU - Renn, Brenna N
AU  - Renn BN
AD  - University of Nevada, Las Vegas, NV, USA.
LA  - eng
PT  - Journal Article
DEP - 20230118
PL  - United States
TA  - Biol Res Nurs
JT  - Biological research for nursing
JID - 9815758
SB  - IM
MH  - Female
MH  - Humans
MH  - Male
MH  - Cohort Studies
MH  - *Electrocardiography
MH  - Hispanic or Latino
MH  - *Metabolic Syndrome/epidemiology
MH  - Public Health
MH  - Risk Factors
OTO - NOTNLM
OT  - Hispanic
OT  - electrocardiogram abnormalities
OT  - metabolic syndrome
EDAT- 2023/01/19 06:00
MHDA- 2023/06/09 06:42
CRDT- 2023/01/18 23:53
PHST- 2023/06/09 06:42 [medline]
PHST- 2023/01/19 06:00 [pubmed]
PHST- 2023/01/18 23:53 [entrez]
AID - 10.1177/10998004231152849 [doi]
PST - ppublish
SO  - Biol Res Nurs. 2023 Jul;25(3):469-479. doi: 10.1177/10998004231152849. Epub 2023 
      Jan 18.