PMID- 36657456
OWN - NLM
STAT- MEDLINE
DCOM- 20230810
LR  - 20230824
IS  - 1439-1902 (Electronic)
IS  - 0171-6425 (Linking)
VI  - 71
IP  - 5
DP  - 2023 Aug
TI  - Single-Center Experience of Pulmonary Endarterectomy for Chronic Thromboembolic 
      Pulmonary Hypertension: The Results from the Tabriz University Medical Sciences 
      (TUMS) CTEPH Program.
PG  - 407-412
LID - 10.1055/s-0042-1760204 [doi]
AB  - INTRODUCTION: Pulmonary endarterectomy (PEA) remains the preferred and 
      potentially curative option for patients with chronic thromboembolic pulmonary 
      hypertension (CTEPH). This study aimed to report the results of PEA for CTEPH in 
      a tertiary center in Tabriz, Iran. METHODS: We analyzed the results of 42 CTEPH 
      patients undergoing PEA, who were enrolled in the Tabriz University of Medical 
      Sciences (TUMS-CTEPH) from January 2016 to October 2020. The main outcome 
      measures included the New York Heart Association (NYHA) functional 
      classification, the 6-Minute Walk Distance, hemodynamic measures in right heart 
      catheterization, morbidity, and mortality. RESULTS: There was a significant 
      improvement in the NYHA function class (2.6 +/- 0.5 vs 1.1 +/- 0.34), mean pulmonary 
      arterial pressure (47.1 +/- 13 vs 27.9 +/- 8 mm Hg), cardiac output (4.3 +/- 1.06 vs 
      5.9 +/- 1.2 L/min), and pulmonary vascular resistance (709.4 +/- 297.5 vs 214 +/- 77 
      dyn s/cm(5)). Fifteen patients (35%) developed complications. The most common 
      complication (10 [23%]) was reperfusion injury. Also, postsurgical mortality was 
      4% during hospital admission and 1-year follow-up. CONCLUSION: This is the first 
      single-center report of PEA from Iran. Post-PEA and 1-year survival were 
      acceptable as a referral center. PEA can be performed safe with low mortality. 
      Greater awareness of PEA and patients' access to experienced CTEPH centers are 
      important issues.
CI  - Thieme. All rights reserved.
FAU - Parvizi, Rezayat
AU  - Parvizi R
AD  - Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, 
      Iran.
FAU - Bilehjani, Eisa
AU  - Bilehjani E
AD  - Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, 
      Iran.
FAU - Mahmoudian, Babak
AU  - Mahmoudian B
AD  - Medical Radiation Sciences Research Team, Tabriz University of Medical Sciences, 
      Tabriz, Iran.
FAU - Koohi, Ata
AU  - Koohi A
AUID- ORCID: 0000-0001-6421-1606
AD  - Tuberculosis and Lung Disease Research Center, Tabriz University of Medical 
      Sciences, Tabriz, Iran.
FAU - Shojaan, Hooriah
AU  - Shojaan H
AD  - Tuberculosis and Lung Disease Research Center, Tabriz University of Medical 
      Sciences, Tabriz, Iran.
FAU - Ansarin, Khalil
AU  - Ansarin K
AD  - Tuberculosis and Lung Disease Research Center, Tabriz University of Medical 
      Sciences, Tabriz, Iran.
FAU - Rashidi, Farid
AU  - Rashidi F
AD  - Tuberculosis and Lung Disease Research Center, Tabriz University of Medical 
      Sciences, Tabriz, Iran.
LA  - eng
PT  - Journal Article
DEP - 20230119
PL  - Germany
TA  - Thorac Cardiovasc Surg
JT  - The Thoracic and cardiovascular surgeon
JID - 7903387
SB  - IM
MH  - Humans
MH  - *Hypertension, Pulmonary/diagnosis/etiology/surgery
MH  - Pulmonary Artery/surgery
MH  - *Pulmonary Embolism/complications/diagnosis/surgery
MH  - Universities
MH  - Treatment Outcome
MH  - Chronic Disease
MH  - Endarterectomy/adverse effects
COIS- None declared.
EDAT- 2023/01/20 06:00
MHDA- 2023/08/10 06:42
CRDT- 2023/01/19 18:42
PHST- 2023/08/10 06:42 [medline]
PHST- 2023/01/20 06:00 [pubmed]
PHST- 2023/01/19 18:42 [entrez]
AID - 10.1055/s-0042-1760204 [doi]
PST - ppublish
SO  - Thorac Cardiovasc Surg. 2023 Aug;71(5):407-412. doi: 10.1055/s-0042-1760204. Epub 
      2023 Jan 19.