PMID- 36660409
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231217
IS  - 2047-2501 (Print)
IS  - 2047-2501 (Electronic)
IS  - 2047-2501 (Linking)
VI  - 11
IP  - 1
DP  - 2023 Dec
TI  - Using nutrigenomics to guide personalized nutrition supplementation for 
      bolstering immune system.
PG  - 4
LID - 10.1007/s13755-022-00208-5 [doi]
LID - 4
AB  - Immunity refers to the ability of the human immune system to resist pathogen 
      infection. Immune system has the basic functions of immune defense, immune self 
      stabilization and immune surveillance. Balanced nutrition is the cornerstone of 
      the immune system to play its immune function, and nutritional intervention is 
      also an important means to maintain and improve immunity. Previous studies have 
      confirmed that T cells have individual differences in recognizing viral antigens 
      of virus infected cells, and the body's response to antigens is controlled by a 
      variety of genetic genes, such as human leukocyte antigen (HLA) genes, immune 
      response (Ir) genes, etc. In this paper, through immunity genetic testing, we 
      screen out genetically susceptible people with low immunity and people with the 
      risk of nutrient metabolism disorders; through using lifestyle questionnaire and 
      physical examination results, we analyze people's physical condition, dietary 
      habits, and exercise habits to evaluate people's nutrient deficiency degree. 
      Then, combining multi-dimensional health data, we evaluate users' immune status 
      and nutritional deficiency risk comprehensively, further, we implemented 
      personalized nutrition intervention on the types and doses of nutritional 
      supplements to improve immunity. We also validated the effectiveness of our 
      personalized nutrition solution through a population-based cohort study.
CI  - (c) The Author(s), under exclusive licence to Springer Nature Switzerland AG 2023, 
      Springer Nature or its licensor (e.g. a society or other partner) holds exclusive 
      rights to this article under a publishing agreement with the author(s) or other 
      rightsholder(s); author self-archiving of the accepted manuscript version of this 
      article is solely governed by the terms of such publishing agreement and 
      applicable law.
FAU - Yang, Jitao
AU  - Yang J
AUID- ORCID: 0000-0003-1387-5909
AD  - School of Information Science, Beijing Language and Culture University, 15 
      Xueyuan Road, Beijing, 100083 China. GRID: grid.443257.3. ISNI: 0000 0001 0741 
      516X
LA  - eng
PT  - Journal Article
DEP - 20230118
PL  - England
TA  - Health Inf Sci Syst
JT  - Health information science and systems
JID - 101638060
PMC - PMC9846659
OTO - NOTNLM
OT  - DNA testing
OT  - Immunity
OT  - Nutrigenetics
OT  - Physical examination
OT  - Precision nutrition
COIS- Conflicts of interestThe author declares no conflict of interest.
EDAT- 2023/01/21 06:00
MHDA- 2023/01/21 06:01
PMCR- 2024/12/01
CRDT- 2023/01/20 02:11
PHST- 2022/02/24 00:00 [received]
PHST- 2022/12/27 00:00 [accepted]
PHST- 2023/01/20 02:11 [entrez]
PHST- 2023/01/21 06:00 [pubmed]
PHST- 2023/01/21 06:01 [medline]
PHST- 2024/12/01 00:00 [pmc-release]
AID - 208 [pii]
AID - 10.1007/s13755-022-00208-5 [doi]
PST - epublish
SO  - Health Inf Sci Syst. 2023 Jan 18;11(1):4. doi: 10.1007/s13755-022-00208-5. 
      eCollection 2023 Dec.