PMID- 36669759
OWN - NLM
STAT- MEDLINE
DCOM- 20230828
LR  - 20230828
IS  - 2055-5822 (Electronic)
IS  - 2055-5822 (Linking)
VI  - 10
IP  - 2
DP  - 2023 Apr
TI  - The use of MitraClip for nonobstructive hypertrophic cardiomyopathy with mixed 
      severe mitral valve regurgitation.
PG  - 1454-1460
LID - 10.1002/ehf2.14291 [doi]
AB  - Reports on the treatment of nonobstructive hypertrophic cardiomyopathy (HCM) and 
      severe mitral valve regurgitation (MR) with transcatheter edge-to-edge repair 
      (TEER) are rare. Herein, we present the case of a 68-year-old Chinese man with 
      nonobstructive HCM admitted to our hospital with dyspnoea [New York Heart 
      Association (NYHA) functional Class IV]. Transthoracic echocardiography indicated 
      severe MR in addition to asymmetric hypertrophy of the left ventricle. Despite 
      administering maximal medical therapy for heart failure, the symptoms were not 
      alleviated; because of the high risk of open surgery, TEER was performed for MR. 
      After 4 months of follow-up, the patient showed a significant improvement in 
      symptoms. Herein, we also discuss and review the pathophysiology and treatment 
      strategies for HCM patients with heart failure.
CI  - (c) 2023 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on 
      behalf of European Society of Cardiology.
FAU - Zeng, Jie
AU  - Zeng J
AUID- ORCID: 0000-0003-2819-8752
AD  - Department of Cardiology, Sichuan Provincial People's Hospital, University of 
      Electronic Science and Technology of China, Chengdu, China.
FAU - Shu, Qinglan
AU  - Shu Q
AD  - Key Laboratory of Ultrasound in Cardiac Electrophysiology and Biomechanics of 
      Sichuan Province, Sichuan Provincial People's Hospital, University of Electronic 
      Science and Technology of China, Chengdu, China.
FAU - Lu, Cong
AU  - Lu C
AD  - Department of Cardiology, Sichuan Provincial People's Hospital, University of 
      Electronic Science and Technology of China, Chengdu, China.
FAU - Wang, Yi
AU  - Wang Y
AD  - Key Laboratory of Ultrasound in Cardiac Electrophysiology and Biomechanics of 
      Sichuan Province, Sichuan Provincial People's Hospital, University of Electronic 
      Science and Technology of China, Chengdu, China.
LA  - eng
PT  - Case Reports
PT  - Research Support, Non-U.S. Gov't
DEP - 20230120
PL  - England
TA  - ESC Heart Fail
JT  - ESC heart failure
JID - 101669191
SB  - IM
MH  - Aged
MH  - Humans
MH  - Male
MH  - *Cardiomyopathy, Hypertrophic/complications/diagnosis/surgery
MH  - Heart Failure/complications/diagnosis
MH  - *Heart Valve Prosthesis Implantation/adverse effects
MH  - Mitral Valve/diagnostic imaging/surgery
MH  - *Mitral Valve Insufficiency/complications/diagnosis/surgery
PMC - PMC10053251
OTO - NOTNLM
OT  - Heart failure
OT  - Hypertrophic cardiomyopathy
OT  - Mitral valve regurgitation
OT  - Transcatheter edge-to-edge repair
COIS- None.
EDAT- 2023/01/21 06:00
MHDA- 2023/03/30 06:11
PMCR- 2023/01/20
CRDT- 2023/01/20 19:32
PHST- 2022/10/23 00:00 [revised]
PHST- 2022/09/12 00:00 [received]
PHST- 2022/11/04 00:00 [accepted]
PHST- 2023/03/30 06:11 [medline]
PHST- 2023/01/21 06:00 [pubmed]
PHST- 2023/01/20 19:32 [entrez]
PHST- 2023/01/20 00:00 [pmc-release]
AID - EHF214291 [pii]
AID - 10.1002/ehf2.14291 [doi]
PST - ppublish
SO  - ESC Heart Fail. 2023 Apr;10(2):1454-1460. doi: 10.1002/ehf2.14291. Epub 2023 Jan 
      20.