PMID- 36674346 OWN - NLM STAT- MEDLINE DCOM- 20230124 LR - 20231117 IS - 1660-4601 (Electronic) IS - 1661-7827 (Print) IS - 1660-4601 (Linking) VI - 20 IP - 2 DP - 2023 Jan 16 TI - Trust and Biomedical Research Engagement of Minority and Under-Represented Communities in Mississippi, USA. LID - 10.3390/ijerph20021592 [doi] LID - 1592 AB - Trust is critical to the development and maintenance of effective research collaborations and community engagement. The purpose of this study was to assess the current attitudes and level of trust pertaining to health research among residents of Central Mississippi, the priority health region for the Research Centers in Minority Institutions (RCMI) Center for Health Disparities Research (RCHDR) at Jackson State University. The cross-sectional study was conducted from November 2021 to April 2022. The data were analyzed using descriptive statistics carried out by SPSS statistical software. A total of 146 participants responded to the survey. The participants were predominately African American (99%) and female (75%). Historical research studies, the researchers' qualities, and potential benefits from participation were factors affecting the level of trust in the research process. Ninety percent (n = 131) expressed that it was important to be involved in the research process, and 98.5% (n = 144) agreed that discussing the research findings with the participants was important for establishing trust in the research process. While trust in the research process does not guarantee participation, trust is a precursor for those who decide to engage in health disparities research. Key findings will be integrated into the RCHDR research agenda to foster further development and implementation of innovative community-based participatory research toward the control and/or prevention of diseases that disproportionately affect minority and under-represented populations in Mississippi. FAU - Antoine-LaVigne, Donna AU - Antoine-LaVigne D AD - RCMI Center for Health Disparities Research, Jackson State University, Jackson, MS 39217, USA. FAU - Hayes, Traci AU - Hayes T AUID- ORCID: 0000-0002-2447-6148 AD - School of Health Professions, University of Southern Mississippi, Hattiesburg, MS 39406, USA. FAU - Fortenberry, Marty AU - Fortenberry M AD - RCMI Center for Health Disparities Research, Jackson State University, Jackson, MS 39217, USA. FAU - Ohikhuai, Evidence AU - Ohikhuai E AD - RCMI Center for Health Disparities Research, Jackson State University, Jackson, MS 39217, USA. FAU - Addison, Clifton AU - Addison C AUID- ORCID: 0000-0001-8949-4980 AD - Jackson Heart Study Graduate Training and Education Center, School of Public Health, Jackson State University, Jackson, MS 39213, USA. FAU - Mozee, Sam Jr AU - Mozee S Jr AD - Mississippi Urban Research Center, Jackson State University, Jackson, MS 39201, USA. FAU - McGill, Dorothy AU - McGill D AD - Innovative Behavioral Services, Ridgeland, MS 39157, USA. FAU - Shanks, Mangle L AU - Shanks ML AD - Shanks Health Housing, Employment, Education & Training Services, Inc., Jackson, MS 39289, USA. FAU - Roby, Christopher AU - Roby C AUID- ORCID: 0000-0001-9373-0309 AD - Mississippi Health Alliance, Byram, MS 39272, USA. FAU - Jenkins, Brenda W Campbell AU - Jenkins BWC AD - Jackson Heart Study Graduate Training and Education Center, School of Public Health, Jackson State University, Jackson, MS 39213, USA. FAU - Tchounwou, Paul B AU - Tchounwou PB AUID- ORCID: 0000-0002-3407-6674 AD - RCMI Center for Health Disparities Research, Jackson State University, Jackson, MS 39217, USA. LA - eng GR - P20 GM103476/GM/NIGMS NIH HHS/United States GR - U54 MD015929/NH/NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural DEP - 20230116 PL - Switzerland TA - Int J Environ Res Public Health JT - International journal of environmental research and public health JID - 101238455 SB - IM MH - Humans MH - Female MH - Mississippi MH - *Trust MH - Cross-Sectional Studies MH - Minority Groups MH - *Biomedical Research PMC - PMC9860548 OTO - NOTNLM OT - African American OT - RCMI programs OT - community engagement OT - research participation OT - trust COIS- The authors declare no conflict of interest. EDAT- 2023/01/22 06:00 MHDA- 2023/01/25 06:00 PMCR- 2023/01/16 CRDT- 2023/01/21 01:23 PHST- 2022/12/08 00:00 [received] PHST- 2022/12/30 00:00 [revised] PHST- 2023/01/04 00:00 [accepted] PHST- 2023/01/21 01:23 [entrez] PHST- 2023/01/22 06:00 [pubmed] PHST- 2023/01/25 06:00 [medline] PHST- 2023/01/16 00:00 [pmc-release] AID - ijerph20021592 [pii] AID - ijerph-20-01592 [pii] AID - 10.3390/ijerph20021592 [doi] PST - epublish SO - Int J Environ Res Public Health. 2023 Jan 16;20(2):1592. doi: 10.3390/ijerph20021592.