PMID- 36675637
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230308
IS  - 2077-0383 (Print)
IS  - 2077-0383 (Electronic)
IS  - 2077-0383 (Linking)
VI  - 12
IP  - 2
DP  - 2023 Jan 16
TI  - A Systematic Review and Meta-Analysis of the Brief Cognitive Assessment for 
      Multiple Sclerosis (BICAMS) International Validations.
LID - 10.3390/jcm12020703 [doi]
LID - 703
AB  - Cognitive impairment is a prevalent and debilitating symptom of multiple 
      sclerosis (MS) but is not routinely addressed in clinical care. The Brief 
      Cognitive Assessment for Multiple Sclerosis (BICAMS) was developed in 2012 to 
      screen and monitor MS patients' cognition. This systematic review and 
      meta-analysis aimed to identify, synthesise, and critically appraise current 
      BICAMS' international validations. The literature search was conducted using 
      PubMed, PsycINFO and Web of Science electronic databases in August 2022. 
      Quantitative, peer-reviewed adult studies, which followed the BICAMS 
      international validation protocol and were published in English, were included. 
      The search identified a total of 203 studies, of which 26 were eligible for 
      inclusion. These reported a total of 2833 adults with MS and 2382 healthy 
      controls (HC). The meta-analysis showed that BICAMS identified impaired cognitive 
      functioning in adults with MS compared to HC for all three subtests: information 
      processing speed (g = 0.854, 95% CI = 0.765, 0.944, p < 0.001), immediate verbal 
      recall (g = 0.566, 95% CI = 0.459, 0.673, p < 0.001) and immediate visual recall 
      (g = 0.566, 95% CI = 0.487, 0.645, p < 0.001). Recruitment sites and strategies 
      limit the generalisability of results. BICAMS is a valid and feasible 
      international MS cognitive assessment.
FAU - Potticary, Hannah
AU  - Potticary H
AD  - Department of Psychology, Royal Holloway, University of London, Egham, Surrey 
      TW20 0EX, UK.
FAU - Langdon, Dawn
AU  - Langdon D
AUID- ORCID: 0000-0003-1128-7417
AD  - Department of Psychology, Royal Holloway, University of London, Egham, Surrey 
      TW20 0EX, UK.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20230116
PL  - Switzerland
TA  - J Clin Med
JT  - Journal of clinical medicine
JID - 101606588
PMC - PMC9863826
OTO - NOTNLM
OT  - BICAMS
OT  - Brief International Cognitive Assessment for Multiple Sclerosis
OT  - cognition
OT  - meta-analysis
OT  - multiple sclerosis
OT  - systematic review
COIS- H.P. declares no conflict of interest. D.L. has received speaker bureau 
      fees/consultancy/research grants from Merck, Novartis, BMS, Bayer, Sanofi, Roche, 
      Biogen.
EDAT- 2023/01/22 06:00
MHDA- 2023/01/22 06:01
PMCR- 2023/01/16
CRDT- 2023/01/21 01:31
PHST- 2022/12/18 00:00 [received]
PHST- 2023/01/03 00:00 [revised]
PHST- 2023/01/09 00:00 [accepted]
PHST- 2023/01/21 01:31 [entrez]
PHST- 2023/01/22 06:00 [pubmed]
PHST- 2023/01/22 06:01 [medline]
PHST- 2023/01/16 00:00 [pmc-release]
AID - jcm12020703 [pii]
AID - jcm-12-00703 [pii]
AID - 10.3390/jcm12020703 [doi]
PST - epublish
SO  - J Clin Med. 2023 Jan 16;12(2):703. doi: 10.3390/jcm12020703.