PMID- 36677901
OWN - NLM
STAT- MEDLINE
DCOM- 20230124
LR  - 20230124
IS  - 1420-3049 (Electronic)
IS  - 1420-3049 (Linking)
VI  - 28
IP  - 2
DP  - 2023 Jan 14
TI  - Validation of a Modified QuEChERS Method for the Determination of Selected 
      Organochlorine Compounds in Honey.
LID - 10.3390/molecules28020842 [doi]
LID - 842
AB  - Honey is considered to be a health-promoting food product. Therefore, it is 
      assumed that it should be free of contaminants. Although the use of 
      organochlorine pesticides (OCPs) was banned a few decades ago in developed 
      countries, persistent organic pollutants (POPs) are still detected in various 
      environmental and biological matrices, including food. These contaminants exhibit 
      toxic properties and bioaccumulate in some food chains. The validation of a 
      modified QuEChERS extraction method was successfully performed for o,p'-DDT, 
      o,p'-DDE, o,p'-DDD, p,p'-DDT, p,p'-DDE, p,p'-DDD, heptachlor and dieldrin. 
      2,2',4,4',5,5'-hexachlorobiphenyl (PCB 153) was used as an internal standard. The 
      modification involved changing the solvent from acetonitrile to n-hexane after 
      extraction. Quantitation was carried out using gas chromatography with an 
      electron capture detector (microECD). The mean recovery values for o,p'-DDT, 
      o,p'-DDE, o,p'-DDD, p,p'-DDT, p,p'-DDE, p,p'-DDD and dieldrin, spiked at 2.9 ng/g 
      and 20 ng/g, ranged from 64.7% to 129.3%, and, for heptachlor spiked at 5.6 ng/g 
      and 20 ng/g, ranged from 68.0% to 88.3%. The relative standard deviation (RSD) 
      for these concentrations did not exceed 20%, and the within-laboratory 
      reproducibility was below 20%, except o,p'-DDE and p,p'-DDT, which were 25.2% and 
      20.7%, respectively. This modified QuEChERS extraction method for selected 
      organochlorine compounds was demonstrated as effective for routine testing in 
      honey.
FAU - Lewinski, Radoslaw
AU  - Lewinski R
AD  - Department of Toxicology and Health Risk Assessment, National Institute of Public 
      Health NIH-National Research Institute, 24 Chocimska, 00-791 Warsaw, Poland.
FAU - Hernik, Agnieszka
AU  - Hernik A
AD  - Department of Toxicology and Health Risk Assessment, National Institute of Public 
      Health NIH-National Research Institute, 24 Chocimska, 00-791 Warsaw, Poland.
FAU - Liszewska, Monika
AU  - Liszewska M
AD  - Department of Toxicology and Health Risk Assessment, National Institute of Public 
      Health NIH-National Research Institute, 24 Chocimska, 00-791 Warsaw, Poland.
FAU - Buckley, Brian
AU  - Buckley B
AD  - Environmental and Occupational Health Sciences Institute, 170 Frelinghuysen Road, 
      Piscataway, NJ 08854, USA.
FAU - Czaja, Katarzyna
AU  - Czaja K
AD  - Department of Toxicology and Health Risk Assessment, National Institute of Public 
      Health NIH-National Research Institute, 24 Chocimska, 00-791 Warsaw, Poland.
FAU - Korcz, Wojciech
AU  - Korcz W
AD  - Department of Toxicology and Health Risk Assessment, National Institute of Public 
      Health NIH-National Research Institute, 24 Chocimska, 00-791 Warsaw, Poland.
FAU - Slomczynska, Anna
AU  - Slomczynska A
AD  - Department of Toxicology and Health Risk Assessment, National Institute of Public 
      Health NIH-National Research Institute, 24 Chocimska, 00-791 Warsaw, Poland.
FAU - Strucinski, Pawel
AU  - Strucinski P
AUID- ORCID: 0000-0001-6023-283X
AD  - Department of Toxicology and Health Risk Assessment, National Institute of Public 
      Health NIH-National Research Institute, 24 Chocimska, 00-791 Warsaw, Poland.
LA  - eng
GR  - FT-1/2022/National Institute of Public Health NIH - National Research Institute/
PT  - Journal Article
DEP - 20230114
PL  - Switzerland
TA  - Molecules
JT  - Molecules (Basel, Switzerland)
JID - 100964009
RN  - D4K93Z1TBH (o,p'-DDT)
RN  - CIW5S16655 (DDT)
RN  - 4M7FS82U08 (Dichlorodiphenyl Dichloroethylene)
RN  - DM084YLQ1L (2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene)
RN  - I0246D2ZS0 (Dieldrin)
RN  - 0 (Hydrocarbons, Chlorinated)
RN  - 0 (Pesticides)
RN  - 7GLS9ACN3L (Heptachlor)
SB  - IM
MH  - DDT/chemistry
MH  - Dichlorodiphenyl Dichloroethylene/analysis
MH  - Dieldrin/analysis
MH  - *Honey/analysis
MH  - Reproducibility of Results
MH  - *Hydrocarbons, Chlorinated/chemistry
MH  - *Pesticides/analysis
MH  - Heptachlor/analysis
PMC - PMC9864146
OTO - NOTNLM
OT  - GC-microECD
OT  - QuEChERS
OT  - honey
OT  - method validation
OT  - organochlorine pesticides
OT  - persistent organic pollutants
COIS- The authors declare no conflict of interest.
EDAT- 2023/01/22 06:00
MHDA- 2023/01/25 06:00
PMCR- 2023/01/14
CRDT- 2023/01/21 01:44
PHST- 2022/11/30 00:00 [received]
PHST- 2023/01/09 00:00 [revised]
PHST- 2023/01/12 00:00 [accepted]
PHST- 2023/01/21 01:44 [entrez]
PHST- 2023/01/22 06:00 [pubmed]
PHST- 2023/01/25 06:00 [medline]
PHST- 2023/01/14 00:00 [pmc-release]
AID - molecules28020842 [pii]
AID - molecules-28-00842 [pii]
AID - 10.3390/molecules28020842 [doi]
PST - epublish
SO  - Molecules. 2023 Jan 14;28(2):842. doi: 10.3390/molecules28020842.