PMID- 36682767 OWN - NLM STAT- MEDLINE DCOM- 20230404 LR - 20230404 IS - 1349-3299 (Electronic) IS - 1349-2365 (Linking) VI - 64 IP - 1 DP - 2023 Mar 31 TI - ST Segment Elevation in a Young Woman with Metaplastic Breast Carcinoma. PG - 114-119 LID - 10.1536/ihj.22-345 [doi] AB - The 12-lead electrocardiogram (ECG) remains a key tool to diagnose ST elevation myocardial infarction (STEMI). However, a variety of other conditions aside from obstructive coronary disease, including hyperkalemia, myocarditis, pericarditis, and Takotsubo and Brugada syndrome, may also cause ST segment elevation, with an incidence rate of 3%-15% and mean age of 45 +/- 14 years. A combination of a detailed past medical history, thorough physical examination, and additional imaging tests may allow physicians to make the correct diagnosis.In this report, we present a case of a 39-year-old woman with metaplastic breast cancer in the process of combined oncological treatment admitted to the emergency department because of general body weakness, chest pain, and accompanying hypotonia with an initial diagnosis of acute coronary syndrome.The ECG at presentation showed ST segment elevation, but owing to the observed neoplastic cachexia and frailty, she was medically managed and the diagnostics were extended to include transthoracic echocardiogram and computed tomography scan. The patient was found to have an external mass that infiltrated into the thoracic wall, pericardium, right ventricle, interventricular septum, and coronary arteries.In cancer patients with chest pain and ST segment elevation, STEMI should not be the only diagnosis taken into account. In our report, using a combination of available cardiac imaging methods, we were able to evaluate the stage of the lesion and coronary involvement. FAU - Wieczorkiewicz, Paulina AU - Wieczorkiewicz P AD - Department of Interventional Cardiology, Medical University of Lodz. FAU - Szymczyk, Konrad AU - Szymczyk K AD - Department of Interventional Cardiology, Medical University of Lodz. FAU - Zielinska, Marzenna AU - Zielinska M AD - Department of Interventional Cardiology, Medical University of Lodz. LA - eng PT - Case Reports PT - Journal Article DEP - 20230123 PL - Japan TA - Int Heart J JT - International heart journal JID - 101244240 SB - IM MH - Female MH - Humans MH - Adult MH - Middle Aged MH - *Myocardial Infarction/diagnosis MH - *ST Elevation Myocardial Infarction/diagnosis/etiology MH - Electrocardiography/methods MH - Arrhythmias, Cardiac MH - *Coronary Artery Disease MH - Chest Pain/diagnosis/etiology MH - *Breast Neoplasms/complications/diagnosis OTO - NOTNLM OT - Coronary artery disease OT - Echocardiogram OT - Young adults EDAT- 2023/01/23 06:00 MHDA- 2023/04/04 06:42 CRDT- 2023/01/22 20:42 PHST- 2023/04/04 06:42 [medline] PHST- 2023/01/23 06:00 [pubmed] PHST- 2023/01/22 20:42 [entrez] AID - 10.1536/ihj.22-345 [doi] PST - ppublish SO - Int Heart J. 2023 Mar 31;64(1):114-119. doi: 10.1536/ihj.22-345. Epub 2023 Jan 23.