PMID- 36683717
OWN - NLM
STAT- MEDLINE
DCOM- 20230124
LR  - 20230124
IS  - 2219-2840 (Electronic)
IS  - 1007-9327 (Print)
IS  - 1007-9327 (Linking)
VI  - 29
IP  - 1
DP  - 2023 Jan 7
TI  - Management of metabolic-associated fatty liver disease: The diabetology 
      perspective.
PG  - 126-143
LID - 10.3748/wjg.v29.i1.126 [doi]
AB  - The metabolic syndrome as a consequence of the obesity pandemic resulted in a 
      substantial increase in the prevalence of metabolic-associated fatty live disease 
      (MAFLD) and type 2 diabetes mellitus (T2DM). Because of the similarity in 
      pathobiology shared between T2DM and MAFLD, both disorders coexist in many 
      patients and may potentiate the disease-related outcomes with rapid progression 
      and increased complications of the individual diseases. In fact, awareness about 
      this coexistence and the risk of complications are often overlooked by both 
      hepatologists and diabetologists. Management of these individual disorders in a 
      patient should be addressed wholistically using an appropriate multidisciplinary 
      team approach involving both the specialists and, when necessary, liaising with 
      dieticians and surgeons. This comprehensive review is to compile the current 
      evidence from a diabetologist's perspective on MAFLD and T2DM and to suggest 
      optimal management strategies.
CI  - (c)The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights 
      reserved.
FAU - Jeeyavudeen, Mohammad Sadiq
AU  - Jeeyavudeen MS
AD  - Department of Endocrinology and Metabolism, University Hospitals of Edinburgh, 
      Edinburgh EH4 2XU, United Kingdom.
FAU - Khan, Shahanas K A
AU  - Khan SKA
AD  - Department of Endocrinology and Metabolism, Lancashire Teaching Hospitals NHS 
      Trust, Preston PR2 9HT, United Kingdom.
FAU - Fouda, Sherouk
AU  - Fouda S
AD  - School of Health and Biomedical Sciences, RMIT University, Melbourne, VIC 3046, 
      Australia.
FAU - Pappachan, Joseph M
AU  - Pappachan JM
AD  - Department of Endocrinology and Metabolism, Lancashire Teaching Hospitals NHS 
      Trust, Preston PR2 9HT, United Kingdom.
AD  - Faculty of Science, Manchester Metropolitan University, Manchester M15 6BH, 
      United Kingdom.
AD  - Faculty of Biology, University of Manchester, Manchester M13 9PL, United Kingdom. 
      drpappachan@yahoo.co.in.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - World J Gastroenterol
JT  - World journal of gastroenterology
JID - 100883448
SB  - IM
MH  - Humans
MH  - *Diabetes Mellitus, Type 2/complications/epidemiology/therapy
MH  - *Metabolic Syndrome/epidemiology/therapy
MH  - *Gastroenterologists
MH  - *Non-alcoholic Fatty Liver Disease/diagnosis/epidemiology/therapy
MH  - *Surgeons
PMC - PMC9850951
OTO - NOTNLM
OT  - Diabetology perspective
OT  - Metabolic syndrome
OT  - Metabolic-associated fatty liver disease
OT  - Nonalcoholic fatty liver disease
OT  - Nonalcoholic steatohepatitis
OT  - Obesity
OT  - Type 2 diabetes mellitus
COIS- Conflict-of-interest statement: The authors have nothing to disclose.
EDAT- 2023/01/24 06:00
MHDA- 2023/01/25 06:00
PMCR- 2023/01/07
CRDT- 2023/01/23 04:16
PHST- 2022/09/20 00:00 [received]
PHST- 2022/11/26 00:00 [revised]
PHST- 2022/12/13 00:00 [accepted]
PHST- 2023/01/23 04:16 [entrez]
PHST- 2023/01/24 06:00 [pubmed]
PHST- 2023/01/25 06:00 [medline]
PHST- 2023/01/07 00:00 [pmc-release]
AID - 10.3748/wjg.v29.i1.126 [doi]
PST - ppublish
SO  - World J Gastroenterol. 2023 Jan 7;29(1):126-143. doi: 10.3748/wjg.v29.i1.126.